Please note that ALL projects with open slots are available to Shapiro applicants. “Non-Shapiro Opportunities” refer to opportunities available for medical students interested in a shorter term (non-summer) projects and yearlong projects.
Summer Research 2025
| Timestamp | Email Address | Mentor First Name | Mentor Last Name | Degree | Title | Phone Number | Dept. | Non-Shapiro Opportunities | Project Information | Primary Department Division | Secondary Department | Secondary Department Division | Co-Mentor Name | Co-Mentor Email | Co-Mentor's Primary Department | Co-Mentor's Primary Department's Division | Project Title | Project Description | Open Slots | Student's Role | Degree of Independence Required | Skills Required | IRB Status of Project | Do you have current NIH or other external funding? | Do you have funding to cover 50% of the Shapiro summer student's stipend? | Do you have resources to provide all needed supplies to support the student research experience? | Are you interested in mentoring non-medical students? | Does your project focus, in part or fully, on medical education? | Is your project related (in part or completely) to public health (e.g., clinical QI, community health, program planning/evaluation, epidemiologic studies)? | Please include names and emails of key staff in your department or lab who will need to be informed of your incoming Shapiro students. | blank 1 | Mentor Information | Response |
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| 11/04/2022 | epetty@wisc.edu | Elizabeth | Petty | MD | Professor, Senior Associate Dean | 608 | Pediatrics | Shorter term projects | Applications of LEAN Quality Improvement to Enhance Outcomes and Optimize Learning: The goal of this project is to use formal evaluation and assessment practices to analyze the implementation and outcomes of innovative programs that are designed to enhance faculty, staff, and/or student education programs. Depending on student interests, existing data sets can be mined or new data can be gathered in areas that are high priority for ongoing quality improvement. Students will work closely with faculty and staff in academic affairs administration and will gain knowledge and skills that are relevant to careers in academic medicine leadership. It is expected that work done by students will lead to opportunities for presentations and publications. Depending on interests of students, students may be able to participate in administrative leadership meetings, shadow in genetics clinic, engage in curriculum development, etc. The research opportunity will be tailored to meet the interests of students who are interested in exploring potential future careers as leaders in academic medicine or medical education. ____________________________________________________________________________ Role - Depends on student’s interests; IRB Status - N/A; Skills - Must have strong computer based skills, communication, and collaboration skills. Expereince with surveys, focus groups, data analysis is a plus. | Pediatrics - Genetics and Metabolism | Other | Academic Affairs - Dean's Office Administration | Applications of LEAN Quality Improvement to Enhance Outcomes and Optimize Learning | The goal of this project is to use formal evaluation and assessment practices to analyze the implementation and outcomes of innovative programs that are designed to enhance faculty, staff, and/or student education programs. Depending on student interests, existing data sets can be mined or new data can be gathered in areas that are high priority for ongoing quality improvement. Students will work closely with faculty and staff in academic affairs administration and will gain knowledge and skills that are relevant to careers in academic medicine leadership. It is expected that work done by students will lead to opportunities for presentations and publications. Depending on interests of students, students may be able to participate in administrative leadership meetings, shadow in genetics clinic, engage in curriculum development, etc. The research opportunity will be tailored to meet the interests of students who are interested in exploring potential future careers as leaders in academic medicine or medical education. | 0 | Depends on student’s interests | Students will meet with mentors formally on a weekly basis and will be expected to make progress on goals independently. Oversight and consultataion with involved faculty and staff will be readily avaiable. | Must have strong computer based skills, communication, and collaboration skills. Expereince with surveys, focus groups, data analysis is a plus. | N/A | Yes | Yes | Yes | Genetic Counseling students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/) | Unsure / Depends | Unsure / Depends | N/A | Elizabeth Petty, epetty@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufZw3OS9lCS7uri7zJAoaBdCeyU06-llc-3Rw64OPmTORz5oAJGP_ALFJ4YOx8Lo1A | |||||
| 12/02/2024 | calee4@wisc.edu | Cathy | Lee-Miller | MD | Assistant Professor | Pediatrics | Shorter term projects, Research Electives for credit | Understanding Decisional Regret in Adolescents with Cancer: Treatment decision-making for adolescents with cancer involves a dynamic interplay between the perspectives and preferences of the adolescent, their families, and their cancer care team. Expanding cognitive maturity and ideas of independence, paired with ongoing parental oversight, creates a unique set of challenges for adolescent healthcare decision-making. The level with which adolescents make decisions in their medical care varies widely, and we believe that levels of regret also vary widely. Previous studies have identified decisional regret in adolescents with cancer, but the underlying sources of this regret remain poorly understood. This study aims to address this knowledge gap by using patient surveys to characterize the burden of decisional regret in adolescents with cancer, and then conducting patient interviews to further explore root causes of regret. This is an ongoing study actively recruiting participants and collecting data. ____________________________________________________________________________ Role - Responsibilities may include observing and/or conducting semi-structured virtual interviews with adolescents, transcribing interview audio recordings, collaborating with other medical students and trainees, assisting with data analysis of patient surveys, and assisting with coding/thematic analysis of interviews. Potential for manuscript preparation and presentation at national conferences.; IRB Status - approved; Skills - Prior experience with qualitative research analysis and/or coding interviews helpful but not required; basic statistics for data analysis; excellent communication skills; comfortable speaking with adolescents; reliable and organized | Hematology/Oncology | Brittany Russell | brussell5@wisc.edu | Other | M4 UWSMPH medical student (class of 2025) | Understanding Decisional Regret in Adolescents with Cancer | Treatment decision-making for adolescents with cancer involves a dynamic interplay between the perspectives and preferences of the adolescent, their families, and their cancer care team. Expanding cognitive maturity and ideas of independence, paired with ongoing parental oversight, creates a unique set of challenges for adolescent healthcare decision-making. The level with which adolescents make decisions in their medical care varies widely, and we believe that levels of regret also vary widely. Previous studies have identified decisional regret in adolescents with cancer, but the underlying sources of this regret remain poorly understood. This study aims to address this knowledge gap by using patient surveys to characterize the burden of decisional regret in adolescents with cancer, and then conducting patient interviews to further explore root causes of regret. This is an ongoing study actively recruiting participants and collecting data. | 0 | Responsibilities may include observing and/or conducting semi-structured virtual interviews with adolescents, transcribing interview audio recordings, collaborating with other medical students and trainees, assisting with data analysis of patient surveys, and assisting with coding/thematic analysis of interviews. Potential for manuscript preparation and presentation at national conferences. | Prior experience with qualitative research analysis and/or coding interviews helpful but not required; basic statistics for data analysis; excellent communication skills; comfortable speaking with adolescents; reliable and organized | approved | No | Yes | Yes | Not currently available to mentor other students | No | Yes | none | Cathy Lee-Miller, calee4@wisc.edu -- Co-Mentor: Brittany Russell brussell5@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueu53S63-4NN906aiG9i6nZNI9NUKUMlB85IRSxMP91XYLZHcMxs3h7FDif_9qh7O8 | |||||
| 12/03/2024 | achiu4@wisc.edu | Alexander | Chiu | MD MPH | Assistant Professor | Surgery | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Developing Interventions to Reduce Disparities in Endocrine Surgery: Surgery for hyperparathyroidism, the only known cure, reduces the risk of osteoporotic fractures, cardiovascular disease, and kidney stones. Surgery is unfortunately severely underutilized and significant disparities exist in who does end up getting treated. We have found that the biggest disparity lays in the referral process from PCP to surgeon. Further qualitative investigation have identified patient understanding of the disease and ability to navigate the health system as the biggest barriers to care. We are therefore focusing on developing patient education and a patient navigation system to overcome these barriers. ____________________________________________________________________________ Role - The student would help spearhead the developing and piloting of a patient navigation system within clinics around the UW system, focusing on clinics serving patients from disadvantaged neighborhoods.; IRB Status - Approved; Skills - No significant background skills needed. Ability to work with a multitude of different people is a real asset | Endocrine Surgery | Developing Interventions to Reduce Disparities in Endocrine Surgery | Surgery for hyperparathyroidism, the only known cure, reduces the risk of osteoporotic fractures, cardiovascular disease, and kidney stones. Surgery is unfortunately severely underutilized and significant disparities exist in who does end up getting treated. We have found that the biggest disparity lays in the referral process from PCP to surgeon. Further qualitative investigation have identified patient understanding of the disease and ability to navigate the health system as the biggest barriers to care. We are therefore focusing on developing patient education and a patient navigation system to overcome these barriers. | 0 | The student would help spearhead the developing and piloting of a patient navigation system within clinics around the UW system, focusing on clinics serving patients from disadvantaged neighborhoods. | moderate | No significant background skills needed. Ability to work with a multitude of different people is a real asset | Approved | No | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | Yes | na | Alexander Chiu, achiu4@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnue522-UIi6e6E5i4SjqzHuGSGggmT-YbmdL2XOEmfk_m1QiHJYBlVKpF-JH7KGtRoU | ||||||||
| 12/03/2024 | agepner@medicine.wisc.edu | Adam | Gepner | MD | Director Gerofit Madison/Assoc. Professor of Medicine | 608 | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Using Central Blood Pressure to Minimize Adverse Events Related to Blood Pressure Treatments: This project goal of this clinical innovation project if to better understand if central blood pressure can be used to minimize medication side effects associated with hypertension treatment. It will take place in the inpatient hospital or ambulatory cardiology clinics at the William S. Middleton VA Hospital. We will recruit ~100 Veterans over age 65 with hypertension followed by cardiology (excluding those with atrial arrhythmia and heart failure with reduced ejection fraction) who have adverse medication side effects or adverse events related to blood pressure treatment (orthostatic hypotension, falls, acute kidney injury, fatigue). We will measure traditional peripheral (brachial) blood pressures and non-invasive central blood pressures using the Atcor device. Outcomes: 1) Differences in brachial vs central blood pressure. 2) Changes the patient’s hypertension treatment plan (increase vs decrease in antihypertensive vs no change (if treatment would have been changed based on brachial BP alone); 3)# of antihypertensive medication related adverse events following treatment changes. https://www.medicine.wisc.edu/cardiovascular-medicine/gepner-research ____________________________________________________________________________ Role - A Shapiro Scholar will be responsible for the following (with guidance and supervision): 1. Reviewing background material and collecting articles on relevant topics including cardiovascular disease prevention, exercise and frailty. 2. Review and understand the Gerofit protocol and study techniques and limitations involved in retrospective analysis. 3. Review and analyze data. 4. Compose a research proposal/abstract/poster/manuscript ; IRB Status - N/A; Skills - Skills with statistics, excel and powerpoint are helpful but not required. Some statistical and programming background is helpful but not required. | Cardiovascular Medicine | Using Central Blood Pressure to Minimize Adverse Events Related to Blood Pressure Treatments | This project goal of this clinical innovation project if to better understand if central blood pressure can be used to minimize medication side effects associated with hypertension treatment. It will take place in the inpatient hospital or ambulatory cardiology clinics at the William S. Middleton VA Hospital. We will recruit ~100 Veterans over age 65 with hypertension followed by cardiology (excluding those with atrial arrhythmia and heart failure with reduced ejection fraction) who have adverse medication side effects or adverse events related to blood pressure treatment (orthostatic hypotension, falls, acute kidney injury, fatigue). We will measure traditional peripheral (brachial) blood pressures and non-invasive central blood pressures using the Atcor device. Outcomes: 1) Differences in brachial vs central blood pressure. 2) Changes the patient’s hypertension treatment plan (increase vs decrease in antihypertensive vs no change (if treatment would have been changed based on brachial BP alone); 3)# of antihypertensive medication related adverse events following treatment changes. https://www.medicine.wisc.edu/cardiovascular-medicine/gepner-research | 0 | A Shapiro Scholar will be responsible for the following (with guidance and supervision): 1. Reviewing background material and collecting articles on relevant topics including cardiovascular disease prevention, exercise and frailty. 2. Review and understand the Gerofit protocol and study techniques and limitations involved in retrospective analysis. 3. Review and analyze data. 4. Compose a research proposal/abstract/poster/manuscript | Moderate - The scholar should be comfortable working independently and with our research team | Skills with statistics, excel and powerpoint are helpful but not required. Some statistical and programming background is helpful but not required. | N/A | Yes | Yes | Yes | UW undergraduates interested in research | No | Yes | Amy Hein: Amy.Hein@va.gov | Adam Gepner, agepner@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucACR-3tgv09wKRZGY1Zvyr-mWnS49MbCilfMZsBgg-jpcWQErq-ROqAoWABJCECJ0 | |||||||
| 12/03/2024 | abdelsayed@wisc.edu | Alaa | Abd-Elsayed | MD, MBA, MPH, CPE, FASA | Medical Director, UW Health Pain Services | 2.163.461.739 | Anesthesiology | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Radiofrequency ablation for headache: We will collect data on a procedure that was invented at UW which is performing radiofrequency ablation for treating different headache conditions. We have large data set that will provide long term outcomes for this this very successful procedure ____________________________________________________________________________ Role - Data collection, writing manuscript and submission; IRB Status - We have waiver and will request an extension; Skills - Data collection and good writing skills | Pain | Anesthesiology | Radiofrequency ablation for headache | We will collect data on a procedure that was invented at UW which is performing radiofrequency ablation for treating different headache conditions. We have large data set that will provide long term outcomes for this this very successful procedure | 0 | Data collection, writing manuscript and submission | Average | Data collection and good writing skills | We have waiver and will request an extension | No | Yes | Yes | RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | Unsure / Depends | Unsure / Depends | jasullivan@wisc.edu, Jeremy Sullivan | Alaa Abd-Elsayed, abdelsayed@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuex-e1rQ5uE2QGQZYrm6HCeeYKxEQj_ZWiWq0PjO03TcowJ0hic9Du8K0ECe8MsF8s | ||||||
| 12/03/2024 | abdelsayed@wisc.edu | Alaa | Abd-Elsayed | MD, MBA, MPH, CPE, FASA | Medical Director, Pain Services | Anesthesiology | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Radiofrequency ablation for peripheral neuralgias: Radiofrequency ablation for treating peripheral neuralgias. We noveled several RFA procedures for treating peripheral neuralgias and we will work on collecting this data and long term outcomes ____________________________________________________________________________ Role - Data collection, manuscript writing and submission; IRB Status - We have waiver; Skills - Data collection and writing | Radiofrequency ablation for peripheral neuralgias | Radiofrequency ablation for treating peripheral neuralgias. We noveled several RFA procedures for treating peripheral neuralgias and we will work on collecting this data and long term outcomes | 0 | Data collection, manuscript writing and submission | Data collection and writing | We have waiver | No | Yes | Yes | RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | Unsure / Depends | Unsure / Depends | jasullivan@wisc.edu, Jeremy Sullivan | Alaa Abd-Elsayed, abdelsayed@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudmsk9pWV85fMDUhnREpaOj2TeH-M71T8bTK4MOJteMIXSU91_81hadgveGVdNRtI0 | ||||||||||
| 12/04/2024 | dempsey@neurosurgery.wisc.edu | Robert | Dempsey | MD | Professor and Chair | 608 | Neurological Surgery | Not currently interested or available for Non-Shapiro research mentoring of medical students | Root Causes of Stroke Risk Disparity in Wisconsin Native Americans: American Indian/Alaska Native (AI/AN) populations across the country experience some of the highest disparities in health and socioeconomic factors compared to other US populations. Native American communities are disproportionately affected with elevated rates of obesity, diabetes, alcohol abuse, cigarette smoking, poverty, and the second lowest rates of educational attainment. These include major risk factors for cerebrovascular disease. The Oneida Nation has previously listed in the 2023-2028 Community Health Improvement Plan (CHIP) that their top priority areas were to reduce chronic health conditions (heart disease, cancer and diabetes). Obesity and diabetes, in addition to hypertension, dyslipidemia, smoking, decreased physical activity, history of vascular disease and/or heart disease and diet are all risk factors that can be controlled or treated to decrease the risk for heart disease and stroke. Individuals at high risk for stroke are also at high risk for vascular cognitive decline and dementia. Carotid atherosclerosis is a risk factor for both stroke and vascular cognitive decline and dementia. Carotid atherosclerosis is thought to contribute to stroke and vascular dementia through mechanisms of ischemia and the release of microemboli due to plaque instability. Ischemia results from plaque in the arterial wall causing narrowing of the carotid artery lumen and thus decreasing blood flow to the brain. Plaque instability is thought to contribute to stroke risk and vascular dementia through the release of microemboli. Thus, it is important to identify individuals at highest risk for this disease, identify how to reduce/modify risk factors for this disease and optimize treatment of this disease for individuals. This proposal will conduct clinical research activities related to stroke risk factors and how interventions such as health education and coaching can contribute to reducing these risk factors and the incidence of stroke in the Native American population. ____________________________________________________________________________ Role - The student's role is to actively participate in the stroke prevention community program at the Oneida Nation - visits occur once a month to the Nation and the rest of the work is on site at UW. This will include reviewing a health history with participants, performing the American Heart Association Quiz with the participant to determine their individual risk factors for stroke, observing cognitive testing performed as part of this study, observing carotid ultrasound examinations, and observing health wellness discussions about resources available for reducing stroke risk factors. These activities will occur if on-site activities are permitted, if not the study activities of health history and stroke risk factor quiz will be virtual, and the MD student will review the health history and stroke risk quiz results with a project team member. The MD student will also perform data entry into the project database. Thus, this project will involve data collection and analysis, literature review, observing outreach activities for the Oneida Nation; with special focus on examining how clinical risk factors present in Native Americans compared to other populations and will evaluate change over a two-year time period looking at how health wellness coaching is related to modifying stroke risk factors. ; IRB Status - approved; Skills - Curious / multitasking / willing to learn new skills / teamwork | Carol Mitchell, PhD | ccm@medicine.wisc.edu | Medicine | Cardiovascular Division | Root Causes of Stroke Risk Disparity in Wisconsin Native Americans | American Indian/Alaska Native (AI/AN) populations across the country experience some of the highest disparities in health and socioeconomic factors compared to other US populations. Native American communities are disproportionately affected with elevated rates of obesity, diabetes, alcohol abuse, cigarette smoking, poverty, and the second lowest rates of educational attainment. These include major risk factors for cerebrovascular disease. The Oneida Nation has previously listed in the 2023-2028 Community Health Improvement Plan (CHIP) that their top priority areas were to reduce chronic health conditions (heart disease, cancer and diabetes). Obesity and diabetes, in addition to hypertension, dyslipidemia, smoking, decreased physical activity, history of vascular disease and/or heart disease and diet are all risk factors that can be controlled or treated to decrease the risk for heart disease and stroke. Individuals at high risk for stroke are also at high risk for vascular cognitive decline and dementia. Carotid atherosclerosis is a risk factor for both stroke and vascular cognitive decline and dementia. Carotid atherosclerosis is thought to contribute to stroke and vascular dementia through mechanisms of ischemia and the release of microemboli due to plaque instability. Ischemia results from plaque in the arterial wall causing narrowing of the carotid artery lumen and thus decreasing blood flow to the brain. Plaque instability is thought to contribute to stroke risk and vascular dementia through the release of microemboli. Thus, it is important to identify individuals at highest risk for this disease, identify how to reduce/modify risk factors for this disease and optimize treatment of this disease for individuals. This proposal will conduct clinical research activities related to stroke risk factors and how interventions such as health education and coaching can contribute to reducing these risk factors and the incidence of stroke in the Native American population. | 0 | The student's role is to actively participate in the stroke prevention community program at the Oneida Nation - visits occur once a month to the Nation and the rest of the work is on site at UW. This will include reviewing a health history with participants, performing the American Heart Association Quiz with the participant to determine their individual risk factors for stroke, observing cognitive testing performed as part of this study, observing carotid ultrasound examinations, and observing health wellness discussions about resources available for reducing stroke risk factors. These activities will occur if on-site activities are permitted, if not the study activities of health history and stroke risk factor quiz will be virtual, and the MD student will review the health history and stroke risk quiz results with a project team member. The MD student will also perform data entry into the project database. Thus, this project will involve data collection and analysis, literature review, observing outreach activities for the Oneida Nation; with special focus on examining how clinical risk factors present in Native Americans compared to other populations and will evaluate change over a two-year time period looking at how health wellness coaching is related to modifying stroke risk factors. | Curious / multitasking / willing to learn new skills / teamwork | approved | No | Yes | Yes | Not currently available to mentor other students | Yes | Yes | Stephanie Wilbrand, PhD - wilbrand@neurosurgery.wisc.edu | Robert Dempsey, dempsey@neurosurgery.wisc.edu -- Co-Mentor: Carol Mitchell, PhD ccm@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuduX6wALysYJvyr5cjn0nM6JN0zfTEhJiA5gjh3CVX4AaW53qlledNsjUwvOZ4zNYQ | |||||
| 12/04/2024 | mwharer@wisc.edu | Matthew | Harer | MD | Associate Professor of Pediatrics | 6.084.176.236 | Pediatrics | Not currently interested or available for Non-Shapiro research mentoring of medical students | Improving neonatal kidney health with NIRS monitoring of kidney oxygenation: We have a database of a recently recruited prospective cohort study of 110 premature neonates born less than 32 weeks gestation. The project will involve a literature review, development of a hypothesis, unique database to answer the question, statistical analysis with graphpad prism, and writing an abstract. Previous projects have included evaluating how ventilation and anemia affect kidney oxygenation and how AKI affects kidney oxygenation. ____________________________________________________________________________ Role - This project will be a combination of multiple types of research and a specific project will be picked after meeting with prospective students: - Enrollment of prospective patients for a clinical research study in the NICU that the IKONIC research group is performing - Active participation in day-to-day research activities for a clinical study (if available) - Chart review for data abstraction - Evaluation of renal oxygenation Students will work closely with Dr. Harer, other IKONIC Research Group team members, and Pediatric Clinical Research Nurse Coordinators to learn skills necessary to complete a comprehensive research project project including but not limited to: - Hypothesis generating research question - Specific aim development - Data collection - Study enrollment - Ethics of research - Basic statistical techniques (including graphing on GraphPad Prism) - Abstract writing - Presentation/Poster development ; IRB Status - Approved; Skills - None | Neonatology | Improving neonatal kidney health with NIRS monitoring of kidney oxygenation | We have a database of a recently recruited prospective cohort study of 110 premature neonates born less than 32 weeks gestation. The project will involve a literature review, development of a hypothesis, unique database to answer the question, statistical analysis with graphpad prism, and writing an abstract. Previous projects have included evaluating how ventilation and anemia affect kidney oxygenation and how AKI affects kidney oxygenation. | 0 | This project will be a combination of multiple types of research and a specific project will be picked after meeting with prospective students: - Enrollment of prospective patients for a clinical research study in the NICU that the IKONIC research group is performing - Active participation in day-to-day research activities for a clinical study (if available) - Chart review for data abstraction - Evaluation of renal oxygenation Students will work closely with Dr. Harer, other IKONIC Research Group team members, and Pediatric Clinical Research Nurse Coordinators to learn skills necessary to complete a comprehensive research project project including but not limited to: - Hypothesis generating research question - Specific aim development - Data collection - Study enrollment - Ethics of research - Basic statistical techniques (including graphing on GraphPad Prism) - Abstract writing - Presentation/Poster development | High | None | Approved | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | No | N/A | Matthew Harer, mwharer@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnue6CS8YfXWhih4xDGd2Qviok67aeWTV5JWXRdBinNqVSei9f92AdYAGm6f0GwXQCoA | |||||||
| 12/04/2024 | sparajuli@medicine.wisc.edu | Sandesh | Parajuli | MD | Associate Professor | Medicine | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Outcomes of kidney transplant recipients among recipients > 70 yrs at age of transplant : As our population is getting older, we are transplanting more and more elderly patients, more than 70 years of age. There are limited data about outcomes of these patients. ____________________________________________________________________________ Role - Will serve as a lead PI in this project, and help on data interpretation, writing abstract, manuscript and presenting this work at different scientific meetings. ; IRB Status - will present to transplant umbrella IRB in few weeks ; Skills - None, | Nephrology | Outcomes of kidney transplant recipients among recipients > 70 yrs at age of transplant | As our population is getting older, we are transplanting more and more elderly patients, more than 70 years of age. There are limited data about outcomes of these patients. | 0 | Will serve as a lead PI in this project, and help on data interpretation, writing abstract, manuscript and presenting this work at different scientific meetings. | None, | will present to transplant umbrella IRB in few weeks | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | Unsure / Depends | Unsure / Depends | N/A | Sandesh Parajuli, sparajuli@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucTqgFS-zxEChxFvrnllan0EJvrC7g7V0Cj_s9dmxX74uy6AOhRlsEdaDlL8_EsEso | |||||||||
| 12/04/2024 | sparajuli@medicine.wisc.edu | Sandesh | Parajuli | MD | Associate Professor | Medicine | Shorter term projects, Research Electives for credit | Long term outcomes of kidney delayed graft function : Kidney-delayed graft function (DGF) is associated with increased risk for rejection, graft failure and suboptimal graft function. However most of the studies are focused on early outcomes. It is not clear how are the outcomes of DGF after 1 year post transplant. ____________________________________________________________________________ Role - Will serve as lead PI, and will need data interpretation, writing abstract and manuscript and presenting these findings at various meetings. ; IRB Status - will apply for Transplant Umbrella IRB in few weeks ; Skills - None- just need energy and enthusiasm | Nephrology-Transplant | Long term outcomes of kidney delayed graft function | Kidney-delayed graft function (DGF) is associated with increased risk for rejection, graft failure and suboptimal graft function. However most of the studies are focused on early outcomes. It is not clear how are the outcomes of DGF after 1 year post transplant. | 0 | Will serve as lead PI, and will need data interpretation, writing abstract and manuscript and presenting these findings at various meetings. | None- just need energy and enthusiasm | will apply for Transplant Umbrella IRB in few weeks | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | Unsure / Depends | Unsure / Depends | N/A | Sandesh Parajuli, sparajuli@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufUfM6VhlGgDv1JyiTK_QKkkwDvQLE6nwNb9PXg95DbtwQwIyWNd5s0KQh9HEx3xbk | |||||||||
| 12/05/2024 | htwedt@wisc.edu | Heidi | Twedt | MD | Professor, Section Chief Applied Clincial Inforamtics | 701 | Medicine | Our new section of Applied Clinical Informatics is working to develop an infrastructure for more student work | Using Large Language Models in analysis of a Physician EHR Satisfaction Survey: UW Health utilizes KLAS Research Arch Collaborative surveys to assess clinician satisfaction with the electronic health record (EHR). For the past three survey iterations, the medical informatics team has manually reviewed and codified responses to the question, “If you could fix three things in the EHR, what would they be?” With advancements in large language models (LLMs), it may now be feasible to automate this process. However, limitations could arise from the LLM's potential lack of understanding of both the physician's work and the EHR's functionality. The student will develop a prompt to effectively codify the data, compare the LLM's output with previous manual codifications, and identify any limitations in fully comprehending the data. This innovative work presents opportunities for presentation at various forums. ____________________________________________________________________________ Role - The student will be provided with resources, including educational materials and access to PhD students, to learn best practices in prompt engineering. Using this knowledge, they will develop a prompt for Microsoft Copilot or a similar large language model (LLM) to analyze data from physician surveys, categorizing the comments into pre-established categories. The student will then analyze the data, comparing it to previous outputs to identify any variations and potential errors in codification by the language model.; IRB Status - N/A; Skills - Communication, Critical Thinking, Problem solving, Willingness to Learn | GIM, Appied Clincal Informatics | Using Large Language Models in analysis of a Physician EHR Satisfaction Survey | UW Health utilizes KLAS Research Arch Collaborative surveys to assess clinician satisfaction with the electronic health record (EHR). For the past three survey iterations, the medical informatics team has manually reviewed and codified responses to the question, “If you could fix three things in the EHR, what would they be?” With advancements in large language models (LLMs), it may now be feasible to automate this process. However, limitations could arise from the LLM's potential lack of understanding of both the physician's work and the EHR's functionality. The student will develop a prompt to effectively codify the data, compare the LLM's output with previous manual codifications, and identify any limitations in fully comprehending the data. This innovative work presents opportunities for presentation at various forums. | 1 | The student will be provided with resources, including educational materials and access to PhD students, to learn best practices in prompt engineering. Using this knowledge, they will develop a prompt for Microsoft Copilot or a similar large language model (LLM) to analyze data from physician surveys, categorizing the comments into pre-established categories. The student will then analyze the data, comparing it to previous outputs to identify any variations and potential errors in codification by the language model. | Moderate: Self-Learning, Collaboration, Problem Solving | Communication, Critical Thinking, Problem solving, Willingness to Learn | N/A | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | No | Julie Herfel | Heidi Twedt, htwedt@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueuWH_bFwhA4U5w14x0jXuTMIZmtsXCxl5M-Nbays1IDl3bpoFdm7eO8f7Yf_8mhaw | |||||||
| 12/05/2024 | schneiderd@surgery.wisc.edu | David | Schneider | MD, MS | Associate Professor | 608 | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Evaluating PROMIS-CAT MyChart Questionnaire Deployment: UW Health has recently acquired Epic’s suite of NIH PROMIS-CAT questionnaires. PROMIS CAT is a computer-based test that uses Item Response Theory (IRT) modeling to adapt the questions a patient is asked based on their previous answers. Therefore, these questionnaires quickly obtain patient reported outcome metrics with the least number of questions possible. The NIH developed these patient reported outcome tools to measure things like quality of life or other disease-specific outcomes. UW Health launched a set of these PROMIS-CAT questionnaires through our patient portal (MyChart) in December for the Rheumatology clinics seeing patients with Lupus. The purpose of this project is to evaluate our deployment in terms of usage, patient completion rates, and provider satisfaction. We will utilize data from our EHR, patient demographics, and provider surveys to evaluate uptake and identify any areas for improvement for future deployment(s) of the PROMIS-CAT surveys. ____________________________________________________________________________ Role - The student will be responsible for data analysis, drafting of a survey, and drafting of abstracts/papers/presentations. Faculty in the Section of Clinical Informatics will assist with these tasks as well as provide the data from the EHR for analysis. ; IRB Status - N/A - QI project; Skills - basic statistics only | Clinical Informatics | Surgery | Endocrine Surgery | Evaluating PROMIS-CAT MyChart Questionnaire Deployment | UW Health has recently acquired Epic’s suite of NIH PROMIS-CAT questionnaires. PROMIS CAT is a computer-based test that uses Item Response Theory (IRT) modeling to adapt the questions a patient is asked based on their previous answers. Therefore, these questionnaires quickly obtain patient reported outcome metrics with the least number of questions possible. The NIH developed these patient reported outcome tools to measure things like quality of life or other disease-specific outcomes. UW Health launched a set of these PROMIS-CAT questionnaires through our patient portal (MyChart) in December for the Rheumatology clinics seeing patients with Lupus. The purpose of this project is to evaluate our deployment in terms of usage, patient completion rates, and provider satisfaction. We will utilize data from our EHR, patient demographics, and provider surveys to evaluate uptake and identify any areas for improvement for future deployment(s) of the PROMIS-CAT surveys. | 1 | The student will be responsible for data analysis, drafting of a survey, and drafting of abstracts/papers/presentations. Faculty in the Section of Clinical Informatics will assist with these tasks as well as provide the data from the EHR for analysis. | Independent with periodic feedback and mentoring | basic statistics only | N/A - QI project | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Yes | Julie Herfel | David Schneider, schneiderd@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuf0fFtgrSuurSCIyhEXElEdnqLkhDyy5BP_5zjcZIppQ8zZJNX9t2zvkfphlojz9U8 | |||||
| 12/05/2024 | jdambach@uwhealth.org | Jason | Dambach | MD | Associate Professor | 6.082.872.250 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Evaluation and Optimization of Health Link training for Phase 1 Medical Students : Our medical student Health Link training is outdated and needs an overhaul. To address this, we need to better understand the electronic health records (EHR) skills required in Phase 1. To achieve this, a survey will be developed for first-year medical students and the faculty leading first-year clinical activities to identify the necessary Health Link skills for Phase 1. Additionally, data will be collected on students' confidence in using the EHR. This data will be gathered from students who completed the historic curriculum (and, eventually, one year later, from those who completed the revised curriculum). The student will then collaborate with our physician informatics team and the UW Health training team to develop an enhanced curriculum. ____________________________________________________________________________ Role - The student will help design the required surveys and meet with some key faculty regarding the needs of students during Phase 1. They will then work with our EOS training team and the Medical Informatics Director of Provider Experience (Dr. Dambach) to develop an updated curriculum that will be used going forward. ; IRB Status - N/A; Skills - Willingness to learn | GIM/Applied Clinical Informatics | Heidi Twedt | htwedt@wisc.edu | Medicine | GIM/Applied Clinical Informatics | Evaluation and Optimization of Health Link training for Phase 1 Medical Students | Our medical student Health Link training is outdated and needs an overhaul. To address this, we need to better understand the electronic health records (EHR) skills required in Phase 1. To achieve this, a survey will be developed for first-year medical students and the faculty leading first-year clinical activities to identify the necessary Health Link skills for Phase 1. Additionally, data will be collected on students' confidence in using the EHR. This data will be gathered from students who completed the historic curriculum (and, eventually, one year later, from those who completed the revised curriculum). The student will then collaborate with our physician informatics team and the UW Health training team to develop an enhanced curriculum. | 1 | The student will help design the required surveys and meet with some key faculty regarding the needs of students during Phase 1. They will then work with our EOS training team and the Medical Informatics Director of Provider Experience (Dr. Dambach) to develop an updated curriculum that will be used going forward. | Moderate | Willingness to learn | N/A | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | Yes | No | Julie Herfel | Jason Dambach, jdambach@uwhealth.org -- Co-Mentor: Heidi Twedt htwedt@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueJPePUpWRqjnmeXlDSbkESzHj_F3e4YkHRx1wjTPAuBycjiDrVOWxT_ZSj4qyPD44 | |||
| 01/09/2025 | dshirley@medicine.wisc.edu | Daniel | Shirley | MD | Associate Professor (CHS) | Medicine | Shorter term projects, Research Electives for credit | Evaluation of Antimicrobial Stewardship Program Domains at King Faisal Hospital in Kigali, Rwanda: Antimicrobial Resistance (AMR) is a worldwide problem and a major focus for healthcare entities like the WHO and CDC. We will utilize a standardized checklist to evaluate the current state of the Antimicrobial Stewardship Program (ASP) at King Faisal Hospital in Kigali, Rwanda and determine barriers to implementation/feasibility of implementation. This will involve administration of the checklist to hospital leadership and interviews to determine barriers to implementation along with feasibility of recommended ASP elements. ____________________________________________________________________________ Role - Travel to Kigali, Rwanda and work through the checklist with colleagues; interview selected leaders to determine barriers to implementation of ASP program elements.; IRB Status - not yet submitted; Skills - Prior foreign travel helpful but not required, interview/communication skills | Infectious Diseases | Dawd Siraj | dssiraj@medicine.wisc.edu | Medicine | Infectious Diseases | Evaluation of Antimicrobial Stewardship Program Domains at King Faisal Hospital in Kigali, Rwanda | Antimicrobial Resistance (AMR) is a worldwide problem and a major focus for healthcare entities like the WHO and CDC. We will utilize a standardized checklist to evaluate the current state of the Antimicrobial Stewardship Program (ASP) at King Faisal Hospital in Kigali, Rwanda and determine barriers to implementation/feasibility of implementation. This will involve administration of the checklist to hospital leadership and interviews to determine barriers to implementation along with feasibility of recommended ASP elements. | 0 | Travel to Kigali, Rwanda and work through the checklist with colleagues; interview selected leaders to determine barriers to implementation of ASP program elements. | High | Prior foreign travel helpful but not required, interview/communication skills | not yet submitted | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Unsure / Depends | N/A | Daniel Shirley, dshirley@medicine.wisc.edu -- Co-Mentor: Dawd Siraj dssiraj@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufFIlt-mVc-d1mV3wrLoc0KmmgZkQcfJpQO55m9HtKaL0VuUfE7EAV3QjjBIkgZnlw | ||||
| 12/07/2024 | rtstriker@wisc.edu | Rob | Striker | MD/PhD | Tailoring Cancer screening based on Immune Resiliance | 608 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Tailoring Cancer screening based on Immune Resiliance: Evidence from both immunocompromised and "older but healthy" people suggest that with aging the immune system declines to varying degrees that can be predicted by simple blood parameters including the CD4/CD8 ratio. We are correlating this information and classifying patients by "Immune resiliance", and seeing if the correlates with cancer incidence, particularly lung cancer, cervical cancer, and certain other types. my website has more information but these 2 youtube videos explain it more fully: 1) 3 min version: https://www.youtube.com/watch?v=bD-sQLZgHBY&t=23s 2) 55 min version: includes 3 min: https://www.youtube.com/watch?v=b5eKbUYCeNs&t=409s ____________________________________________________________________________ Role - collection of health records and data carpentry; IRB Status - already submitted; Skills - Excel, Epic access | Infectious Diseases | Tailoring Cancer screening based on Immune Resiliance | Evidence from both immunocompromised and "older but healthy" people suggest that with aging the immune system declines to varying degrees that can be predicted by simple blood parameters including the CD4/CD8 ratio. We are correlating this information and classifying patients by "Immune resiliance", and seeing if the correlates with cancer incidence, particularly lung cancer, cervical cancer, and certain other types. my website has more information but these 2 youtube videos explain it more fully: 1) 3 min version: https://www.youtube.com/watch?v=bD-sQLZgHBY&t=23s 2) 55 min version: includes 3 min: https://www.youtube.com/watch?v=b5eKbUYCeNs&t=409s | 0 | collection of health records and data carpentry | Moderate | Excel, Epic access | already submitted | American Cancer society funding is pending | No (plan to use Dean's Office Funds) | Yes | PhD students | Unsure / Depends | Yes | Liana Nash, LCNash@medicine.wisc.edu | Rob Striker, rtstriker@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueLKSUou8KJahlMTwzJzeaHpyubz1_mDiRcrTgBZOe6DbVEwRA54bE_IAscX-7Ub8s | |||||||
| chod@surgery.wisc.edu | Daniel | Cho | MD, PhD | Assistant Professor | Surgery | Shorter term projects, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Association of Orofacial Clefts and their Association with Environmental Contaminants in the State of Wisconsin: Orofacial clefts (OFC) are a spectrum of congenital facial differences including clefts of the lip and palate, impacting 1 in 700 infants. These have significant physical, psychological and socio-economic impacts on patients and families. The multidisciplinary Craniofacial Anomalies Clinic (CFAC) at the American Family Children’s Hospital (AFCH) provides cleft care for a significant portion of Wisconsin. The providers have noted that there is a higher rate and unusual presentations of OFC in Wisconsin. A preliminary analysis of patients treated at AFCH revealed a 2:1 ratio of unilateral:bilateral clefts, which is a significant contrast to the expected 9:1 ratio. It is widely accepted that OFC result from the complex interplay between genetic and environmental factors but there is little data on the effect of environmental contaminants on the development of OFC. We hypothesize that there are high rates of environmental contamination in specific areas of Wisconsin, and that both environmental contamination and sociodemographic disparities will be associated with an increased incidence of OFC in specific areas of our state. The first stage of our study has demonstrated that the rate of OFC was 400% higher in the Fox River Valley region but has decreased by 50% since the completion of an EPA Superfund Cleanup while the rate of OFC in the Madison area has doubled over the past 8 years. This Shapiro project will focus on the second stage of this project, which is to evaluate environmental contaminants in the Fox Rivery Valley and Madison areas that may be associated with OFC for preliminary screening in vitro assays of orofacial development. ____________________________________________________________________________ Role - Development of collaboration with environmental scientists at UW, the state government, and EPA; interfacing with developmental biology collaborator; IRB Status - N/A; Skills - Experience with statistical analysis preferred but not required | Plastic Surgery | Catharine | Garland | Surgery | Plastic Surgery | Association of Orofacial Clefts and their Association with Environmental Contaminants in the State of Wisconsin | Orofacial clefts (OFC) are a spectrum of congenital facial differences including clefts of the lip and palate, impacting 1 in 700 infants. These have significant physical, psychological and socio-economic impacts on patients and families. The multidisciplinary Craniofacial Anomalies Clinic (CFAC) at the American Family Children’s Hospital (AFCH) provides cleft care for a significant portion of Wisconsin. The providers have noted that there is a higher rate and unusual presentations of OFC in Wisconsin. A preliminary analysis of patients treated at AFCH revealed a 2:1 ratio of unilateral:bilateral clefts, which is a significant contrast to the expected 9:1 ratio. It is widely accepted that OFC result from the complex interplay between genetic and environmental factors but there is little data on the effect of environmental contaminants on the development of OFC. We hypothesize that there are high rates of environmental contamination in specific areas of Wisconsin, and that both environmental contamination and sociodemographic disparities will be associated with an increased incidence of OFC in specific areas of our state. The first stage of our study has demonstrated that the rate of OFC was 400% higher in the Fox River Valley region but has decreased by 50% since the completion of an EPA Superfund Cleanup while the rate of OFC in the Madison area has doubled over the past 8 years. This Shapiro project will focus on the second stage of this project, which is to evaluate environmental contaminants in the Fox Rivery Valley and Madison areas that may be associated with OFC for preliminary screening in vitro assays of orofacial development. | 0 | Development of collaboration with environmental scientists at UW, the state government, and EPA; interfacing with developmental biology collaborator | Experience with statistical analysis preferred but not required | N/A | Yes | Yes | Yes | MPH students, PhD students | No | Yes | Darcy Middleton (middletonda@surgery.wisc.edu) | Daniel Cho, chod@surgery.wisc.edu -- Co-Mentor: Catharine Garland | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucqFRDGGKpZz34BQccQT6V4M8bIcXCTsvG67rDAPJWvN8v43B_GhAbl-mvv4MSoNmw | ||||||
| 12/09/2024 | bernatz@ortho.wisc.edu | James | Bernatz | MD | Assistant Professor | 2.628.531.519 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | Outcomes of Bone Health Optimization Intervention on Orthopedic Surgery Patients: We are seeking a Shapiro Student to perform a retrospective study of our Bone Health Optimization patients. Many patients have osteoporosis, and prior to performing major orthopedic surgery (joint replacement, spine fusion, etc), we assess and treat their bone to hopefully obtain better outcomes after surgery. The purpose of this project is to evaluate those outcomes via a retrospective review of this already identified population. This work will require data extraction from Health Link, developing a RedCap database and working with our biostatistician to evaluate the data. The student should expect to write at least 1 first author publication during the summer with likely more follow-up projects available to be involved with. ____________________________________________________________________________ Role - We are seeking a Shapiro Student to perform a retrospective study of our Bone Health Optimization patients. Many patients have osteoporosis, and prior to performing major orthopedic surgery (joint replacement, spine fusion, etc), we assess and treat their bone to hopefully obtain better outcomes after surgery. The purpose of this project is to evaluate those outcomes via a retrospective review of this already identified population. This work will require data extraction from Health Link, developing a RedCap database and working with our biostatistician to evaluate the data. The student should expect to write at least 1 first author publication during the summer with likely more follow-up projects available to be involved with.; IRB Status - Submitted, pending; Skills - None, we'll teach you! | Orthopedic Spine surgery | Outcomes of Bone Health Optimization Intervention on Orthopedic Surgery Patients | We are seeking a Shapiro Student to perform a retrospective study of our Bone Health Optimization patients. Many patients have osteoporosis, and prior to performing major orthopedic surgery (joint replacement, spine fusion, etc), we assess and treat their bone to hopefully obtain better outcomes after surgery. The purpose of this project is to evaluate those outcomes via a retrospective review of this already identified population. This work will require data extraction from Health Link, developing a RedCap database and working with our biostatistician to evaluate the data. The student should expect to write at least 1 first author publication during the summer with likely more follow-up projects available to be involved with. | 0 | We are seeking a Shapiro Student to perform a retrospective study of our Bone Health Optimization patients. Many patients have osteoporosis, and prior to performing major orthopedic surgery (joint replacement, spine fusion, etc), we assess and treat their bone to hopefully obtain better outcomes after surgery. The purpose of this project is to evaluate those outcomes via a retrospective review of this already identified population. This work will require data extraction from Health Link, developing a RedCap database and working with our biostatistician to evaluate the data. The student should expect to write at least 1 first author publication during the summer with likely more follow-up projects available to be involved with. | Moderate | None, we'll teach you! | Submitted, pending | No | Yes | Yes | Not currently available to mentor other students | No | No | N/A | James Bernatz, bernatz@ortho.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufbgo5eVestfKbOZFMjcprSTwZ5-WH8kLmmgJN3bA3UfHX5pWBaFEvaX-yTU0t0CBo | |||||||
| 12/09/2024 | dchen@uwhealth.org | Derrick | Chen | MD | Clinical Microbiology Projects | Pathology and Laboratory Medicine | Shorter term projects, Research Electives for credit | Research Projects in Clinical Microbiology (Multiple): Please contact Dr. Chen if you are interested in doing a research project in clinical microbiology. There are multiple projects available on a variety of topics, and he can discuss them with you to see if any are of interest. Also, if there is something you're particularly interested in that’s not listed, a custom project can be created. Prior research experience is not needed, and Dr. Chen will guide the trainee through all the steps of research, from project design to publication. Each project will only have one trainee, so the trainee will learn about and be integral to all parts of the project. Most projects will involve data collection and chart review, so knowledge of and access to Excel and Epic/Hyperlink is generally required. Projects usually have a high chance of being accepted for presentation at a national conference (usually ASM Microbe and/or ID Week). Manuscript potential depends on the project and the data that is collected. Examples of projects include, but are not limited to: (1) Utility of Legionella cultures, (2) Utility of fecal leukocytes test, (3) Impact of 16S sequencing for unidentifiable isolates. ____________________________________________________________________________ Role - Data collection, data analysis, abstract writing; IRB Status - n/a; Skills - Excel, Epic Chart Review | Research Projects in Clinical Microbiology (Multiple) | Please contact Dr. Chen if you are interested in doing a research project in clinical microbiology. There are multiple projects available on a variety of topics, and he can discuss them with you to see if any are of interest. Also, if there is something you're particularly interested in that’s not listed, a custom project can be created. Prior research experience is not needed, and Dr. Chen will guide the trainee through all the steps of research, from project design to publication. Each project will only have one trainee, so the trainee will learn about and be integral to all parts of the project. Most projects will involve data collection and chart review, so knowledge of and access to Excel and Epic/Hyperlink is generally required. Projects usually have a high chance of being accepted for presentation at a national conference (usually ASM Microbe and/or ID Week). Manuscript potential depends on the project and the data that is collected. Examples of projects include, but are not limited to: (1) Utility of Legionella cultures, (2) Utility of fecal leukocytes test, (3) Impact of 16S sequencing for unidentifiable isolates. | 1 | Data collection, data analysis, abstract writing | Any | Excel, Epic Chart Review | n/a | No | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students | No | No | n/a | Derrick Chen, dchen@uwhealth.org -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufZdsRclu1wgX-TVXqeGNvokko_XyoMmj53lMK6ZXlbjASzIKoYsRw5f40I7KNj-Ag | |||||||||
| 12/11/2024 | ctmichels@medicine.wisc.edu | Collin | Michels | MD | Assistant Professor | Emergency Medicine | Shorter term projects | OUD System of Care: The aim of this study is to evaluate the system of care of patients with opioid use disorder (OUD). Previous work has identified barriers and facilitators to buprenorphine initiation, overdose education and naloxone distribution (OEND) in the emergency department (ED), but less is known about the recently implemented EMS-initiated buprenorphine practices. We will conduct a retrospective chart review of patients who received EMS-initiated buprenorphine to better understand patient and EMS factors including EMS team characteristics, geographic location, known adverse events, transport vs refusal of transport. There is potential for an economic analysis of field OUD administration. The EMS evaluation will include qualitative and quantitative (mixed methods) research. First, we will conduct interviews with a small number of paramedics involved in the program to better understand barriers, facilitators, and perceived needs related to buprenorphine field initiation. The data collected in these interviews will be used to create and deploy a comprehensive survey that will go out to all of the paramedics. Additionally, we will conduct a post-intervention survey of ED staff (MDs, PAs, RNs) to re-assess current level of comfort with buprenorphine initiation and OEND following multiple educational and EHR clinical decision support interventions. The survey was initially deployed during the summer of 2022, and we will compare knowledge, attitudes and level of comfort from the pre-intervention and post-intervention surveys. Please note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. ____________________________________________________________________________ Role - Involvement in survey design and analysis, data analysis, contributions to manuscript writing, and poster presentations.; IRB Status - Will be IRB approved by Spring 2025. ; Skills - Experience in survey design/administration, data cleaning, and analysis is useful but not required. Training will be provided. | Elizabeth Salisbury-Afshar | elizabeth.salisbury-afshar@fammed.wisc.edu | Family Medicine and Community Health | OUD System of Care | The aim of this study is to evaluate the system of care of patients with opioid use disorder (OUD). Previous work has identified barriers and facilitators to buprenorphine initiation, overdose education and naloxone distribution (OEND) in the emergency department (ED), but less is known about the recently implemented EMS-initiated buprenorphine practices. We will conduct a retrospective chart review of patients who received EMS-initiated buprenorphine to better understand patient and EMS factors including EMS team characteristics, geographic location, known adverse events, transport vs refusal of transport. There is potential for an economic analysis of field OUD administration. The EMS evaluation will include qualitative and quantitative (mixed methods) research. First, we will conduct interviews with a small number of paramedics involved in the program to better understand barriers, facilitators, and perceived needs related to buprenorphine field initiation. The data collected in these interviews will be used to create and deploy a comprehensive survey that will go out to all of the paramedics. Additionally, we will conduct a post-intervention survey of ED staff (MDs, PAs, RNs) to re-assess current level of comfort with buprenorphine initiation and OEND following multiple educational and EHR clinical decision support interventions. The survey was initially deployed during the summer of 2022, and we will compare knowledge, attitudes and level of comfort from the pre-intervention and post-intervention surveys. Please note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. | 0 | Involvement in survey design and analysis, data analysis, contributions to manuscript writing, and poster presentations. | Experience in survey design/administration, data cleaning, and analysis is useful but not required. Training will be provided. | Will be IRB approved by Spring 2025. | No | Yes | Yes | Not currently available to mentor other students | No | Yes | Andrea Gilmore-Bykovskyi (algilmore@medicine.wisc.edu), Phoebe Natzke (pnatzke@medicine.wisc.edu) | Collin Michels, ctmichels@medicine.wisc.edu -- Co-Mentor: Elizabeth Salisbury-Afshar elizabeth.salisbury-afshar@fammed.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufJPQd0GEv-nsZmTtipqKYh3jgjn1gfZmBoFYEGRRtpS8oiAX5ixTl9GXsRdTEZ1Jc | |||||||
| 12/11/2024 | baschnagel@humonc.wisc.edu | Andrew | Baschnagel | MD | Associate Professor | 6.082.629.169 | Human Oncology | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | AI approach to predicting lung cancer metastases.: The objective of the project is to combine CT and MRI imaging data with pathological and genomic data to predict the development of metastases in patients with non-small cell lung cancer. Deep learning methods will be used to analyze data. There are opportunities for authorship on abstracts and papers. Previous students have been very successful. Project is great for those interested in medical oncology, radiation oncology, thoracic surgical oncology, radiology, pathology or pulmonary medicine. ____________________________________________________________________________ Role - Update clinical database. If student has coding or bioinformatic skills they can get involved in the computation aspect of the project.; IRB Status - IRB approved; Skills - Database entry. Coding and bioinformatics skill sets are welcomed but not required. | AI approach to predicting lung cancer metastases. | The objective of the project is to combine CT and MRI imaging data with pathological and genomic data to predict the development of metastases in patients with non-small cell lung cancer. Deep learning methods will be used to analyze data. There are opportunities for authorship on abstracts and papers. Previous students have been very successful. Project is great for those interested in medical oncology, radiation oncology, thoracic surgical oncology, radiology, pathology or pulmonary medicine. | 0 | Update clinical database. If student has coding or bioinformatic skills they can get involved in the computation aspect of the project. | Student will meet with mentor once a week. Opportunity for clinical shadowing. | Database entry. Coding and bioinformatics skill sets are welcomed but not required. | IRB approved | No | Yes | Yes | Genetic Counseling students, MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | No | Karen Steiner; Liz Forget | Andrew Baschnagel, baschnagel@humonc.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuew6R3EnfTw76t3oYQIPNNxDXnmVVj16svpCpo7aeRqpTqeWbIgsFzW9IECNj_MKIo | ||||||||
| 12/12/2024 | candrews@medicine.wisc.edu | Colleen | Andrews | MD, MPH | Assistant Professor | Emergency Medicine | Shorter term projects | Factors influencing cervical cancer screening and follow-up in rural Guatemala: Cervical cancer is a preventable, treatable cancer, yet worldwide, many women do not undergo routine cervical cancer screening, leading to significant morbidity and mortality. San Lucas Toliman, Guatemala is a rural town with a predominantly indigenous population. In partnership with local community health workers (CHWs) and providers, a team from UW established a cervical cancer screening program in San Lucas Toliman. This program provides wraparound care including human papillomavirus (HPV) screening, diagnosis via visual exam, same-day treatment, and follow-up. CHWs keep track of enrolled women through a mobile health application. Preliminary data from this program shows a higher rate of HPV than previous data from other Guatemalan studies, as well as a number of women lost to follow-up after initial screening. We aim to conduct a qualitative assessment to evaluate factors affecting participation for eligible women, including factors influencing screening and follow-up. For women who have been lost to follow-up, we will clarify their needs and help connect them back to care if they are interested. We will analyze additional data to describe HPV rates and subtypes. We will prioritize these aims based on local healthcare colleague preferences. ____________________________________________________________________________ Role - Conduct 2-3 structured interviews (potential to do additional interviews if time permits), assist CHWs in coordinating follow-up for interested women who were lost to follow-up, transcribe interviews, work with the team to develop a codebook, become familiar with Nvivo software and participate in coding. Contribute to manuscript preparation. Assist in analyzing the additional data collected to describe HPV rates and subtypes in the community. ; IRB Status - In progress; Skills - Previous experience in qualitative methods or motivational interviewing would be useful but is not required. | Global Health | Jessica Schmidt | jschmidt@medicine.wisc.edu | Factors influencing cervical cancer screening and follow-up in rural Guatemala | Cervical cancer is a preventable, treatable cancer, yet worldwide, many women do not undergo routine cervical cancer screening, leading to significant morbidity and mortality. San Lucas Toliman, Guatemala is a rural town with a predominantly indigenous population. In partnership with local community health workers (CHWs) and providers, a team from UW established a cervical cancer screening program in San Lucas Toliman. This program provides wraparound care including human papillomavirus (HPV) screening, diagnosis via visual exam, same-day treatment, and follow-up. CHWs keep track of enrolled women through a mobile health application. Preliminary data from this program shows a higher rate of HPV than previous data from other Guatemalan studies, as well as a number of women lost to follow-up after initial screening. We aim to conduct a qualitative assessment to evaluate factors affecting participation for eligible women, including factors influencing screening and follow-up. For women who have been lost to follow-up, we will clarify their needs and help connect them back to care if they are interested. We will analyze additional data to describe HPV rates and subtypes. We will prioritize these aims based on local healthcare colleague preferences. | 1 | Conduct 2-3 structured interviews (potential to do additional interviews if time permits), assist CHWs in coordinating follow-up for interested women who were lost to follow-up, transcribe interviews, work with the team to develop a codebook, become familiar with Nvivo software and participate in coding. Contribute to manuscript preparation. Assist in analyzing the additional data collected to describe HPV rates and subtypes in the community. | Previous experience in qualitative methods or motivational interviewing would be useful but is not required. | In progress | No | Yes | Yes | Not currently available to mentor other students | No | Yes | Andrea Gilmore-Bykovskyi (algilmore@medicine.wisc.edu), Phoebe Natzke, (pnatzke@medicine.wisc.edu) | Colleen Andrews, candrews@medicine.wisc.edu -- Co-Mentor: Jessica Schmidt jschmidt@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueech5uElwtuLDW6m0a8KC_WWY_njGiuGlIkUpzf5IAusteQwlt87LdoWHoUI_Ili4 | |||||||
| 12/12/2024 | agepner@medicine.wisc.edu | Adam | Gepner | MD | Assoc. Professor of Medicine | 6.085.778.048 | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Understanding blood pressure and hemodynamic assessments in older Veterans based on Hypertensive Status - FAST Vets Study.: The FAST-Vet study enrolled 180 Veterans over 60 years old with and without hypertension. Veterans underwent an arterial stress test where vascular parameters were measured before and after exercise (day 1) and sublingual nitroglycerin (day 2). Arterial stiffness and cardiovascular hemodynamics were obtained. We have several ongoing sub-aims that where a Shapiro Scholar could help test and analyze novel non-invasive diagnostics to personalize hypertension care in older adults. Our lab challenges the existing dogma that blood pressure are best measured at rest. Potential Specific Projects: 1. Evaluate differences and similarities between arterial stiffness parameters following exercise or nitroglycerin administration based on hypertension status. 2. Evaluate heart rate deceleration post-exercise (a marker of autonomic function) and associations with magnitude of change in arterial stiffness with exercise. A scholar could use these skills to non-invasively improve diagnosis, treatment goals, and quality of life in an older at-risk adults. Website: https://www.medicine.wisc.edu/cardiovascular-medicine/gepner-research ____________________________________________________________________________ Role - A Shapiro Scholar will be responsible for the following (with guidance and supervision): 1. Reviewing background material and collecting articles on relevent topics. 2. Review and understand FAST-Vet protocol and study techniques. 3. Review and analyze data on a subaims of the FAST-Vets study (see projects ideas above). 4. Compose a research proposal/abstract/manuscript ; IRB Status - Approved; Skills - Some statistical and programming background is helpful but not required. | Cardiovascular Medicine | Understanding blood pressure and hemodynamic assessments in older Veterans based on Hypertensive Status - FAST Vets Study. | The FAST-Vet study enrolled 180 Veterans over 60 years old with and without hypertension. Veterans underwent an arterial stress test where vascular parameters were measured before and after exercise (day 1) and sublingual nitroglycerin (day 2). Arterial stiffness and cardiovascular hemodynamics were obtained. We have several ongoing sub-aims that where a Shapiro Scholar could help test and analyze novel non-invasive diagnostics to personalize hypertension care in older adults. Our lab challenges the existing dogma that blood pressure are best measured at rest. Potential Specific Projects: 1. Evaluate differences and similarities between arterial stiffness parameters following exercise or nitroglycerin administration based on hypertension status. 2. Evaluate heart rate deceleration post-exercise (a marker of autonomic function) and associations with magnitude of change in arterial stiffness with exercise. A scholar could use these skills to non-invasively improve diagnosis, treatment goals, and quality of life in an older at-risk adults. Website: https://www.medicine.wisc.edu/cardiovascular-medicine/gepner-research | 0 | A Shapiro Scholar will be responsible for the following (with guidance and supervision): 1. Reviewing background material and collecting articles on relevent topics. 2. Review and understand FAST-Vet protocol and study techniques. 3. Review and analyze data on a subaims of the FAST-Vets study (see projects ideas above). 4. Compose a research proposal/abstract/manuscript | The scholar should be comfortable working independently and with our research team | Some statistical and programming background is helpful but not required. | Approved | Yes | Yes | Yes | MPH students, PhD students, UW undergraduates interested in research | No | Yes | amy.hein@VA.gov | Adam Gepner, agepner@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufpMQkOvgnkEsHeZ09DojD-9YfLCbzsaGBh4UI4UYLbmEyVe6074yhurK3O_n3n1AQ | |||||||
| 12/12/2024 | jcregg@wisc.edu | Jared | Cregg | BSE Biomedical Engineering, PhD Neuroscience | Assistant Professor | Neuroscience | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), longer research projects are dependent on a good match | Mapping and Modulating Brainstem Circuits: A Translational Approach to Parkinson’s Disease Therapy: Our research focuses on understanding the neural circuits that control movement and translating this knowledge into therapies for Parkinson’s Disease (PD). To bridge the gap between animal models and human application, our first aim is to establish the relationship between motor circuits in mice and non-human primates by creating a molecular atlas of macaque brainstem targets of basal ganglia output. Specifically, we will use MERFISH, a cutting-edge imaging technique, to analyze two key brainstem regions—the pedunculopontine nucleus (PPN) and the rostral pontine reticular formation (PnO)—to identify cell types involved in locomotor speed and turning. These findings will build on existing mouse datasets to map primate brainstem circuitry, providing a roadmap for future functional studies. Our second aim focuses on enabling precise manipulation of these brainstem circuits by developing a library of enhancer elements that drive targeted gene expression in non-human primates. By leveraging ATAC-seq, we will define the chromatin landscape of PPN and PnO neurons to identify specific enhancer sequences, which will then be validated in vivo using viral vectors in mouse models. This work will set the stage for translational studies to test therapeutic strategies for restoring motor function in PD. ____________________________________________________________________________ Role - The student’s role in this project will involve contributing to key experimental and analytical aspects of the research. They prepare tissue, image, and collect data for MERFISH analysis of macaque brainstem nuclei. The student will also gain hands-on experience in molecular techniques such as RNAScope for RNA target validation. This role offers the opportunity to develop technical skills in cutting-edge molecular neuroscience while contributing to impactful translational research.; IRB Status - N/A; Skills - Bench skills: tissue histology, pipetting. Experience in data analysis. | Neurology | Mapping and Modulating Brainstem Circuits: A Translational Approach to Parkinson’s Disease Therapy | Our research focuses on understanding the neural circuits that control movement and translating this knowledge into therapies for Parkinson’s Disease (PD). To bridge the gap between animal models and human application, our first aim is to establish the relationship between motor circuits in mice and non-human primates by creating a molecular atlas of macaque brainstem targets of basal ganglia output. Specifically, we will use MERFISH, a cutting-edge imaging technique, to analyze two key brainstem regions—the pedunculopontine nucleus (PPN) and the rostral pontine reticular formation (PnO)—to identify cell types involved in locomotor speed and turning. These findings will build on existing mouse datasets to map primate brainstem circuitry, providing a roadmap for future functional studies. Our second aim focuses on enabling precise manipulation of these brainstem circuits by developing a library of enhancer elements that drive targeted gene expression in non-human primates. By leveraging ATAC-seq, we will define the chromatin landscape of PPN and PnO neurons to identify specific enhancer sequences, which will then be validated in vivo using viral vectors in mouse models. This work will set the stage for translational studies to test therapeutic strategies for restoring motor function in PD. | 0 | The student’s role in this project will involve contributing to key experimental and analytical aspects of the research. They prepare tissue, image, and collect data for MERFISH analysis of macaque brainstem nuclei. The student will also gain hands-on experience in molecular techniques such as RNAScope for RNA target validation. This role offers the opportunity to develop technical skills in cutting-edge molecular neuroscience while contributing to impactful translational research. | 60% | Bench skills: tissue histology, pipetting. Experience in data analysis. | N/A | No | Yes | No | Not currently available to mentor other students | No | No | Rebecca Welch; rebecca.welch@wisc.edu | Jared Cregg, jcregg@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnue4I2d3lk5WveOtbriuYUedkJGxzi3RutfjbcAk6STrQ2fGKd0wTFNZlbq6I8pFVs4 | ||||||||
| 12/12/2024 | krisjon.olson@wisc.edi | Krisjon | Olson | Ph.D. | Assistant Professor | 5.102.297.337 | Pediatrics | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Health Equity and Resilience – Championing Action and Research for Empowerment of Wisconsin Women with Congenital Heart Disease (HER-CARE): People with congenital heart disease (CHD) now survive into adulthood; a tidal shift over fifty years. Survivorship inequities for women and people with disabilities, however, persist with over half lost in the transition from pediatric to adult care. requiring emergency and intensive care after long periods without follow-up, a disparity identified by our team and others. We work with youth, families, scientists and clinicians to co-create interventions that prioritize gender equity and accessibility. Together, we designed an accessible care model to address gaps between pediatric and adult care: communication, supported decision-making, and community collaboration. We are currently testing a toolkit designed and endorsed by youth with disabilities, their caregivers, community service providers, doctors, and nurses. Our results will be shared through the Forward Pediatric Alliance so that fewer women with CHD are lost in Wisconsin’s healthcare system. This groundbreaking joint venture for shared pediatric cardiac and adult congenital heart care services and research across the state will allow us to scale hospital policies, quality improvement efforts, tools, and community supports. By changing how doctors support young women and their families, and partnering with women and girls to lead, we aim to create health access for all. It could dramatically improve care in Wisconsin, where 13% of children live with a disability, and more than half are cared for at home by an aging mother. Our powerful network of 800 survivors, pediatric and adult providers, clinical and social scientists, and community partners will support locally led change to advance a global movement for CHD survivorship. ____________________________________________________________________________ Role - Explore the intersection of gender, disability, or access to care in CHD survivorship. ; IRB Status - Approved; Skills - Qualitative coding skills/NVivo a plus | Cardiology | Health Equity and Resilience – Championing Action and Research for Empowerment of Wisconsin Women with Congenital Heart Disease (HER-CARE) | People with congenital heart disease (CHD) now survive into adulthood; a tidal shift over fifty years. Survivorship inequities for women and people with disabilities, however, persist with over half lost in the transition from pediatric to adult care. requiring emergency and intensive care after long periods without follow-up, a disparity identified by our team and others. We work with youth, families, scientists and clinicians to co-create interventions that prioritize gender equity and accessibility. Together, we designed an accessible care model to address gaps between pediatric and adult care: communication, supported decision-making, and community collaboration. We are currently testing a toolkit designed and endorsed by youth with disabilities, their caregivers, community service providers, doctors, and nurses. Our results will be shared through the Forward Pediatric Alliance so that fewer women with CHD are lost in Wisconsin’s healthcare system. This groundbreaking joint venture for shared pediatric cardiac and adult congenital heart care services and research across the state will allow us to scale hospital policies, quality improvement efforts, tools, and community supports. By changing how doctors support young women and their families, and partnering with women and girls to lead, we aim to create health access for all. It could dramatically improve care in Wisconsin, where 13% of children live with a disability, and more than half are cared for at home by an aging mother. Our powerful network of 800 survivors, pediatric and adult providers, clinical and social scientists, and community partners will support locally led change to advance a global movement for CHD survivorship. | 1 | Explore the intersection of gender, disability, or access to care in CHD survivorship. | Independent | Qualitative coding skills/NVivo a plus | Approved | CHER Grant, pending Pivot grant | No (plan to use Dean's Office Funds) | Yes | DPT students, Genetic Counseling students, MPH students, PhD students, UW undergraduates interested in research | No | Yes | hansari@wisc.edu | Krisjon Olson, krisjon.olson@wisc.edi -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueLPL4m4gyfRIsAJWMpRyr8Gbv_tavPvrFsB0ZDmWdnwJ3ozr6CoayX4uVnml1zuX4 | |||||||
| 12/12/2024 | krisjon.olson@wisc.edu | Krisjon | Olson | PhD | Assistant Professor | 5.102.297.337 | Pediatrics | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Ethical, Legal, and Social Issues in the Opportunity to Reach Individuals with Genetic dyslipidemia during Infancy and the Newborn period to find Familial Hypercholesterolemia: 1 in 300 individuals have Familial Hypercholesterolemia (FH), which identified early, makes an otherwise fatal condition highly treatable. Universal screening during childhood is widely recommended, however fewer than 10% are found through current screening at age 8-12. Our team developed a novel two-stage screening algorithm using deidentified newborn dried blood spot specimens. Yet the benefits and harms of disclosing results to family members and their newborns, and policy implications, remain understudied. Our community-based research will examine the ethical, legal, and social issues of FH diagnosis. Integrating ethnographic findings into FH research that engages children, parents, adult survivors, clinicians, hospital, and public health stakeholders will significantly improve our disparity focused study design NICHD PA-21-115, “Natural History of Disorders Screenable in the Newborn Period” and enhance anthropological understanding of newborn biological variation. ____________________________________________________________________________ Role - Possible roles: Qualitative Data Collection and Analysis: Assist in conducting semi-structured interviews with clinicians, and public health professionals.Support transcription and coding of interviews using qualitative analysis software. Community Engagement and Participant Recruitment: Help recruit study participants from diverse populations through outreach to community organizations and clinical partners. Coordinate with the Familial Hypercholesterolemia Foundation and clinic partners to ensure participant diversity. Medical Record Review: Conduct retrospective chart reviews using the Pediatric Preventive Cardiology Clinic database.Identify and categorize themes related to FH care during the first five years of life. Dissemination and Reporting:Assist in drafting a presentation or manuscript summarizing preliminary findings. Contribute to the development of educational materials aimed at clinicians and families. ; IRB Status - Approved; Skills - Experience with medical record review; qualitative research; NVivo a plus | Cardiology | Amy Peterson | apeterson@wisc.edu | Pediatrics | Cardiology | Ethical, Legal, and Social Issues in the Opportunity to Reach Individuals with Genetic dyslipidemia during Infancy and the Newborn period to find Familial Hypercholesterolemia | 1 in 300 individuals have Familial Hypercholesterolemia (FH), which identified early, makes an otherwise fatal condition highly treatable. Universal screening during childhood is widely recommended, however fewer than 10% are found through current screening at age 8-12. Our team developed a novel two-stage screening algorithm using deidentified newborn dried blood spot specimens. Yet the benefits and harms of disclosing results to family members and their newborns, and policy implications, remain understudied. Our community-based research will examine the ethical, legal, and social issues of FH diagnosis. Integrating ethnographic findings into FH research that engages children, parents, adult survivors, clinicians, hospital, and public health stakeholders will significantly improve our disparity focused study design NICHD PA-21-115, “Natural History of Disorders Screenable in the Newborn Period” and enhance anthropological understanding of newborn biological variation. | 2 | Possible roles: Qualitative Data Collection and Analysis: Assist in conducting semi-structured interviews with clinicians, and public health professionals.Support transcription and coding of interviews using qualitative analysis software. Community Engagement and Participant Recruitment: Help recruit study participants from diverse populations through outreach to community organizations and clinical partners. Coordinate with the Familial Hypercholesterolemia Foundation and clinic partners to ensure participant diversity. Medical Record Review: Conduct retrospective chart reviews using the Pediatric Preventive Cardiology Clinic database.Identify and categorize themes related to FH care during the first five years of life. Dissemination and Reporting:Assist in drafting a presentation or manuscript summarizing preliminary findings. Contribute to the development of educational materials aimed at clinicians and families. | Independent | Experience with medical record review; qualitative research; NVivo a plus | Approved | Yes | No (plan to use Dean's Office Funds) | Yes | DPT students, Genetic Counseling students, MPH students, PhD students, UW undergraduates interested in research | No | No | hansari@wisc.edu | Krisjon Olson, krisjon.olson@wisc.edu -- Co-Mentor: Amy Peterson apeterson@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudBm3ExCXyfRGwj9HUDknSQE6GcbVasXauOr-MVS8p0n5Q7IVKFcw-CDoEP877aVA4 | |||
| 12/12/2024 | epetty@wisc.edu | Elizabeth | Petty | MD | Professor, Pediatrics, Division of Genetics; Senior Associate Dean Academic Affairs | 6.082.632.480 | Pediatrics | Shorter term projects, Research Electives for credit | Advancing Wellbeing, Equity, and Inclusion in Health Professions Education and Academic Medicine : Projects through my group fall in three major areas with a common themes of (1) advancing wellbeing, equity, and inclusion in health professions education and academic medicine and (2) optimizing health outcomes for patients and populations through research and quality improvement projects. Depending on a student's interests and experience, a student working with me and members of my team will be able to shape their specific project within any one of these three domains: 1) Improving the Learning Environment and Leveling the Playing Field to Promote Flourishing of Health Professions Learners: Quality improvement projects in this area focus on how we can use existing data to inform deeper exploration of issues that impact learner wellbeing. Recent work of students in this area has led to accepted and published manuscripts on student burn-out, minority tax, and gender differences. Recent work has also begun exploring preparation for matriculation to medical school, student services for other genetic counseling education programs, burdens related to the cost of education, and interprofessional education opportunities. Projects in this area would build upon existing work and data sets, as well as leverage opportunities to gather new data in emerging areas relevant to education delivery and student programming. 2) Advancing LGBTQIA+ and Gender Expansive Health Equity: Ongoing quality improvement research projects, from curriculum evaluation and professional development to student support and inclusive practices, designed to address gaps and opportunities in a changing environment are one focus of research and can build upon recent or existing projects that I have been working with students on. Recent published/accepted projects in this area include those examining medical education nationally and locally as well as exploring use of gender inclusive language in health care and the need for ongoing professional development of health professionals. I am also interested in health outcomes of LGBTQIA+ populations and public health perspectives related to optimizing health across LGBTQIA+ and gender diverse populations. 3) Addressing Unmet Needs in Clinical Genetics and Human Genomics. Projects in this domain include examination of unmet workforce and professional development issues to address gaps in access and service, evaluate issues impacting effective delivery of genetic services including genetic counseling, and further characterizing unique conditions to advance knowledge in clinical and molecular genetics. Recent publishes/accepted projects in this domain have addressed issues around disability education, telemedicine, syndrome characterization, and evaluation of policies and practices for the delivery of genetic services. I am happy to meet with students to discuss their interests and to guide the development and the execution of projects that fall into any of the domains above where I have research interests and experience. Co-mentors and team collaborators will be engaged on specific projects as relevant. ____________________________________________________________________________ Role - Working with the mentorship team, health profession degree students will play a key role in defining specific approaches and goals related to their part in the project. They will be mentored to lead their project and be involved in all aspects from data collection and analysis to creating presentations and publications resulting from their work. Undergraduate students or students with limited time will have more specific guided tasks on projects and less independence. ; IRB Status - Yes where relevant; Skills - Outstanding communication and time management skills are necessary. Experience with critical literature reviews, quality improvement work, survey design and development, focus groups, knowledge/experience with qualitative and quantitative data analysis, previous research, and/or project management experience is helpful. Specific project skill development will be provided depending on the project chosen by the student and the skills and techniques required for successful completion of the project. | Genetics and Metabolism | Academic Affairs | Health Professions Education | Co-mentors will be identified as relevant to specific project | Advancing Wellbeing, Equity, and Inclusion in Health Professions Education and Academic Medicine | Projects through my group fall in three major areas with a common themes of (1) advancing wellbeing, equity, and inclusion in health professions education and academic medicine and (2) optimizing health outcomes for patients and populations through research and quality improvement projects. Depending on a student's interests and experience, a student working with me and members of my team will be able to shape their specific project within any one of these three domains: 1) Improving the Learning Environment and Leveling the Playing Field to Promote Flourishing of Health Professions Learners: Quality improvement projects in this area focus on how we can use existing data to inform deeper exploration of issues that impact learner wellbeing. Recent work of students in this area has led to accepted and published manuscripts on student burn-out, minority tax, and gender differences. Recent work has also begun exploring preparation for matriculation to medical school, student services for other genetic counseling education programs, burdens related to the cost of education, and interprofessional education opportunities. Projects in this area would build upon existing work and data sets, as well as leverage opportunities to gather new data in emerging areas relevant to education delivery and student programming. 2) Advancing LGBTQIA+ and Gender Expansive Health Equity: Ongoing quality improvement research projects, from curriculum evaluation and professional development to student support and inclusive practices, designed to address gaps and opportunities in a changing environment are one focus of research and can build upon recent or existing projects that I have been working with students on. Recent published/accepted projects in this area include those examining medical education nationally and locally as well as exploring use of gender inclusive language in health care and the need for ongoing professional development of health professionals. I am also interested in health outcomes of LGBTQIA+ populations and public health perspectives related to optimizing health across LGBTQIA+ and gender diverse populations. 3) Addressing Unmet Needs in Clinical Genetics and Human Genomics. Projects in this domain include examination of unmet workforce and professional development issues to address gaps in access and service, evaluate issues impacting effective delivery of genetic services including genetic counseling, and further characterizing unique conditions to advance knowledge in clinical and molecular genetics. Recent publishes/accepted projects in this domain have addressed issues around disability education, telemedicine, syndrome characterization, and evaluation of policies and practices for the delivery of genetic services. I am happy to meet with students to discuss their interests and to guide the development and the execution of projects that fall into any of the domains above where I have research interests and experience. Co-mentors and team collaborators will be engaged on specific projects as relevant. | 2 | Working with the mentorship team, health profession degree students will play a key role in defining specific approaches and goals related to their part in the project. They will be mentored to lead their project and be involved in all aspects from data collection and analysis to creating presentations and publications resulting from their work. Undergraduate students or students with limited time will have more specific guided tasks on projects and less independence. | Students will be guided and mentored for their research through formal weekly project meetings and more frequent information meetings and virtual discussion. Students will be expected to make progress on research independently between meetings following project timelines aligned with goals. | Outstanding communication and time management skills are necessary. Experience with critical literature reviews, quality improvement work, survey design and development, focus groups, knowledge/experience with qualitative and quantitative data analysis, previous research, and/or project management experience is helpful. Specific project skill development will be provided depending on the project chosen by the student and the skills and techniques required for successful completion of the project. | Yes where relevant | Yes | Yes | Yes | DPT students, Genetic Counseling students, MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/) | Yes | Yes | Susan Jeannette | Elizabeth Petty, epetty@wisc.edu -- Co-Mentor: Co-mentors will be identified as relevant to specific project | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufLHvC2WcEp6dMMalRB_Ph6WI-A5yR2UOLrtR4vjrFILDKDCRcpnmqVNj5_7XAzDBw | ||||
| bpgolden@medicine.wisc.edu | Blair | Golden | MD, MS | Assistant Professor | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Portrayals of cognition in hospitalized patients in TV medical dramas: Numerous studies have demonstrated the ability of popular media (e.g., medical drama TV shows) to influence public perceptions of health issues and the expectations of family members and patients when in healthcare settings. Hospitalized patients frequently experience acute changes in their cognition due to delirium and other medical causes, yet patients and families may not be prepared or familiar with these changes. The goal of this project is to understand how changes in cognition are depicted and discussed on medical dramas on TV. ____________________________________________________________________________ Role - The study will participate in structured data abstraction from medical TV dramas related to this project as well as a parallel project on family engagement in medical dramas (being performed by another Shapiro student supervised by Dr. Kruser). They will be responsible for identifying any issues in data abstraction and participating in iterative refinement of the abstraction tool as needed. They will guide analysis of abstracted findings.; IRB Status - Approved (Non-Human Subjects Research); Skills - Qualitative research and prior writing experience preferred | Hospital Medicine | Jacky Kruser (Assistant Professor) | jkruser@wisc.edu | Medicine | Pulmonary | Portrayals of cognition in hospitalized patients in TV medical dramas | Numerous studies have demonstrated the ability of popular media (e.g., medical drama TV shows) to influence public perceptions of health issues and the expectations of family members and patients when in healthcare settings. Hospitalized patients frequently experience acute changes in their cognition due to delirium and other medical causes, yet patients and families may not be prepared or familiar with these changes. The goal of this project is to understand how changes in cognition are depicted and discussed on medical dramas on TV. | 0 | The study will participate in structured data abstraction from medical TV dramas related to this project as well as a parallel project on family engagement in medical dramas (being performed by another Shapiro student supervised by Dr. Kruser). They will be responsible for identifying any issues in data abstraction and participating in iterative refinement of the abstraction tool as needed. They will guide analysis of abstracted findings. | Qualitative research and prior writing experience preferred | Approved (Non-Human Subjects Research) | Yes | Yes | Yes | Not currently available to mentor other students | No | Unsure / Depends | Brooke Johnson (bnjohnson@medicine.wisc.edu) | Blair Golden, bpgolden@medicine.wisc.edu -- Co-Mentor: Jacky Kruser (Assistant Professor) jkruser@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucqx5MSn6BEOo4DpjpAmS8V-K3PZ-ND4KLTm4-AMPuj_xiTFo5vYqDw7BwC_Z-Wxb4 | ||||||
| mlubner@uwhealth.org | Meghan | Lubner | MD | Professor of Radiology | Radiology | Research Electives for credit | Abdominal Imaging and Intervention Projects: (Drs. Lubner & Pickhardt will discuss a variety of potential projects with the prospective Shapiro student, and a mutual decision on a specific project will be made, reflecting interest, need, and feasibility. Please note completing a Shapiro research project in the radiology department comes with a variety of additional learning opportunities including small group mentoring sessions, faculty lectures, clinical shadowing, financial support for meetings, etc) 1. General CT projects: Clinical projects to include topics like perforation and distribution of gas following optical colonoscopy, assessment of perineural invasion in GI malignancies, Workflow/technology projects around novel CT techniques such as dual energy CT, photon counting CT, CT protocols(e.g. biphasic CT, CT UGI series etc), deep learning reconstruction techniques (DLIR), CT dose, consequences of changing kV and impact on HU measurements. 2. Image guided Biopsy: Assemble data from US and CT guided biopsy data bases, assess diagnostic yield, complications/safety, examples would include concordance of targeted liver biopsy, bowel biopsy, complications of biopsy of hepatocellular carcinoma 3. CT radiologic pathologic correlation project: Work on direct rad path correlation for CT of ex vivo surgical specimens (this may be a longer term project), some machine and deep learning involved 4. CT colonography related projects 5. Miscellaneous clinical projects, ex ileal pouch project looking at post procedure imaging appearance and complications; findings and complications on imaging post CAR-T cell therapy, imaging appearance and implications following treatment with novel targeted chemotherapy (e.g. FRFR inhibitors etc) ____________________________________________________________________________ Role - Image Analysis, medical record search, data collection, collation, organization ; IRB Status - Approved or soon to be approved; Skills - data collection, navigation of PACs and Medical record, Microsoft suite tools (word, ppt, excel) | Perry Pickhardt | ppickhardt2@uwhealth.org | Radiology | Abdominal Imaging and Intervention Projects | (Drs. Lubner & Pickhardt will discuss a variety of potential projects with the prospective Shapiro student, and a mutual decision on a specific project will be made, reflecting interest, need, and feasibility. Please note completing a Shapiro research project in the radiology department comes with a variety of additional learning opportunities including small group mentoring sessions, faculty lectures, clinical shadowing, financial support for meetings, etc) 1. General CT projects: Clinical projects to include topics like perforation and distribution of gas following optical colonoscopy, assessment of perineural invasion in GI malignancies, Workflow/technology projects around novel CT techniques such as dual energy CT, photon counting CT, CT protocols(e.g. biphasic CT, CT UGI series etc), deep learning reconstruction techniques (DLIR), CT dose, consequences of changing kV and impact on HU measurements. 2. Image guided Biopsy: Assemble data from US and CT guided biopsy data bases, assess diagnostic yield, complications/safety, examples would include concordance of targeted liver biopsy, bowel biopsy, complications of biopsy of hepatocellular carcinoma 3. CT radiologic pathologic correlation project: Work on direct rad path correlation for CT of ex vivo surgical specimens (this may be a longer term project), some machine and deep learning involved 4. CT colonography related projects 5. Miscellaneous clinical projects, ex ileal pouch project looking at post procedure imaging appearance and complications; findings and complications on imaging post CAR-T cell therapy, imaging appearance and implications following treatment with novel targeted chemotherapy (e.g. FRFR inhibitors etc) | 0 | Image Analysis, medical record search, data collection, collation, organization | Moderate | data collection, navigation of PACs and Medical record, Microsoft suite tools (word, ppt, excel) | Approved or soon to be approved | No | Yes | Yes | Not currently available to mentor other students | No | No | Max Olin (MOlin@uwhealth.org) | Meghan Lubner, mlubner@uwhealth.org -- Co-Mentor: Perry Pickhardt ppickhardt2@uwhealth.org | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucbzYv-4lNnJJxy-x2ovG3iwCmgezbeWbCDwoST5CynqJkKoAVpEuojJFStNPQzKoY | |||||||
| tamplin@wisc.edu | Owen | Tamplin | PhD | Assistant Professor | Cell and Regenerative Biology | Not currently interested or available for Non-Shapiro research mentoring of medical students, Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Blood stem cell microenvironment: One of the projects in our lab is to understand how GABA metabolite is produced in the bone marrow microenvironment and how it regulates blood stem cell proliferation and differentiation. The GABA system in the bone marrow also changes during aging. Blood stem cell regulation has translational importance for transplantation, response to disease, and changes in the blood system during aging. https://tamplin.crb.wisc.edu/ ____________________________________________________________________________ Role - Working with a graduate student to harvest bone marrow from different mouse mutants and analysis using flow cytometry.; IRB Status - N/A; Skills - Basic lab techniques, such pipetting, making solutions, dilution calculations, etc. | Blood stem cell microenvironment | One of the projects in our lab is to understand how GABA metabolite is produced in the bone marrow microenvironment and how it regulates blood stem cell proliferation and differentiation. The GABA system in the bone marrow also changes during aging. Blood stem cell regulation has translational importance for transplantation, response to disease, and changes in the blood system during aging. https://tamplin.crb.wisc.edu/ | 1 | Working with a graduate student to harvest bone marrow from different mouse mutants and analysis using flow cytometry. | Moderate to high. | Basic lab techniques, such pipetting, making solutions, dilution calculations, etc. | N/A | Yes | Yes | Yes | PhD students, UW undergraduates interested in research | No | No | Colleen Dickey , DENEEN M WELLIK , MICHAEL K FERREE | Owen Tamplin, tamplin@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuemNdzqKDaM-62gsLKsGuW9pr_Llhb9TKJ8Ta7FZA1MH5EewQIi50YDfISijWDbv88 | ||||||||||
| achamorfaw@medicine.wisc.edu | Stephannie | Acha-Morfaw | MD | Assistant Professor | Emergency Medicine | Shorter term projects | Variability in Clinical Exposure to Patients with Diverse Social Identities in Emergency Medicine Residency: Previous studies have noted that clinical experiences of Emergency Medicine residents are highly variable. This could suggest that residents may graduate with relative deficits in exposure, confidence, and competence with caring for patients from different backgrounds. However, to our knowledge, this has never been shown empirically. This study will be a retrospective analysis on data pulled from the electronic health record. The goal is to evaluate variability in clinical exposure to patients of different backgrounds amongst all Emergency Medicine residents who worked in the ED from 2016-2023 and completed their residency training. Primary outcomes of interest are variability in resident clinical exposure as the first resident assigned to a visit for individual patient demographics including gender, age, weight, race, sexual orientation, socioeconomic background, high ED utilization, social vulnerability index, social deprivation index, rural living environment, and non-English speaking status. This project will provide experience and education in the area of data processing and review, medical education manuscript writing, and presenting analysis at the local and possibly national level. Please Note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. ____________________________________________________________________________ Role - Students will help to review data and identify compelling information we can use to tell a story of why the variability seen matters for trainees, creating visuals of data, such as tables, charts, whisker plots, and assist with writing the manuscript.; IRB Status - IRB review required; Skills - Previous experience creating figures would be useful but is not required. | Ben Schnapp | bschnapp@medicine.wisc.edu | Emergency Medicine | Variability in Clinical Exposure to Patients with Diverse Social Identities in Emergency Medicine Residency | Previous studies have noted that clinical experiences of Emergency Medicine residents are highly variable. This could suggest that residents may graduate with relative deficits in exposure, confidence, and competence with caring for patients from different backgrounds. However, to our knowledge, this has never been shown empirically. This study will be a retrospective analysis on data pulled from the electronic health record. The goal is to evaluate variability in clinical exposure to patients of different backgrounds amongst all Emergency Medicine residents who worked in the ED from 2016-2023 and completed their residency training. Primary outcomes of interest are variability in resident clinical exposure as the first resident assigned to a visit for individual patient demographics including gender, age, weight, race, sexual orientation, socioeconomic background, high ED utilization, social vulnerability index, social deprivation index, rural living environment, and non-English speaking status. This project will provide experience and education in the area of data processing and review, medical education manuscript writing, and presenting analysis at the local and possibly national level. Please Note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. | 0 | Students will help to review data and identify compelling information we can use to tell a story of why the variability seen matters for trainees, creating visuals of data, such as tables, charts, whisker plots, and assist with writing the manuscript. | Previous experience creating figures would be useful but is not required. | IRB review required | No | Yes | Yes | Not currently available to mentor other students | Yes | No | Andrea Gilmore-Bykovskyi (algilmore@medicine.wisc.edu), Phoebe Natzke (pnatzke@medicine.wisc.edu) | Stephannie Acha-Morfaw, achamorfaw@medicine.wisc.edu -- Co-Mentor: Ben Schnapp bschnapp@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucrdOU-MbA2SYZn7pHM-3jbEmqNQLOr210vYkUBQtEn6lpa2TtnvLCyiRBLbHHpNGQ | ||||||||
| bpatter@medicine.wisc.edu | Brian | Patterson | MD MPH | Associate Professor | Emergency Medicine | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Evaluation of Referral Appropriateness of an AI Emergency Department Falls Prevention Decision Support Tool: This project is part of the Emergency Care Systems Lab (ECSL), a groundbreaking initiative dedicated to advancing emergency care through innovative technologies and research. The focus of this project is on assessing the appropriateness of referrals generated by a Clinical Decision Support (CDS) tool designed to identify older adults at risk of falls in the emergency department (ED) using a machine-learning algorithm. The two specific aims for this project are to evaluate referral appropriateness and to investigate factors influencing appropriate or inappropriate referrals, including clinician decision making and workflow integration. The findings will help optimize the CDS tool’s effectiveness and improve patient outcomes, aligning with ECSL's mission to drive impactful, evidence-based interventions. Please Note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. ____________________________________________________________________________ Role - The selected student will complete detailed chart reviews, perform thematic analysis, and contribute to a comprehensive report or presentation summarizing findings and recommendations.; IRB Status - IRB approved; Skills - Experience with thematic analysis is preferred but not required. | Hanna Barton, Scientist | hbarton@wisc.edu | Emergency Medicine | Evaluation of Referral Appropriateness of an AI Emergency Department Falls Prevention Decision Support Tool | This project is part of the Emergency Care Systems Lab (ECSL), a groundbreaking initiative dedicated to advancing emergency care through innovative technologies and research. The focus of this project is on assessing the appropriateness of referrals generated by a Clinical Decision Support (CDS) tool designed to identify older adults at risk of falls in the emergency department (ED) using a machine-learning algorithm. The two specific aims for this project are to evaluate referral appropriateness and to investigate factors influencing appropriate or inappropriate referrals, including clinician decision making and workflow integration. The findings will help optimize the CDS tool’s effectiveness and improve patient outcomes, aligning with ECSL's mission to drive impactful, evidence-based interventions. Please Note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. | 1 | The selected student will complete detailed chart reviews, perform thematic analysis, and contribute to a comprehensive report or presentation summarizing findings and recommendations. | Experience with thematic analysis is preferred but not required. | IRB approved | No | Yes | Yes | PhD students, UW undergraduates interested in research | No | No | Andrea Gilmore-Bykovskyi (algilmore@medicine.wisc.edu), Phoebe Natzke (pnatzke@medicine.wisc.edu) | Brian Patterson, bpatter@medicine.wisc.edu -- Co-Mentor: Hanna Barton, Scientist hbarton@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuffNwR_JiGW1DgY1-xqHLtZHN7zhcTJZKdKGsoUdvjMDx0bgn26CS9VDO-yOoOrN5I | ||||||||
| bpatter@medicine.wisc.edu | Brian | Patterson | MD MPH | Associate Professor | Emergency Medicine | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Post-Academic Detailing Interviews: Evaluating Impact and Improving Workflows : This project is part of the Emergency Care Systems Lab (ECSL), a transdisciplinary initiative at the forefront of advancing emergency care through innovative research and operational partnerships. The focus of this project is on conducting post-academic detailing interviews with providers who previously participated in academic detailing sessions. These interviews aim to evaluate the sessions' impact on provider understanding, confidence, and workflow integration of the Falls Risk Best Practice Alert (BPA) and referral process. The findings will inform improvements to academic detailing and BPA design, contributing to ECSL's mission of driving transformative healthcare solutions. This project offers an opportunity to contribute to cutting-edge research within the emergency care systems lab, evaluating the effects of an AI-driven intervention to improve public health. Students will gain hands-on experience in qualitative research, deepen their understanding of healthcare workflows and automated decision support, and develop skills applicable to both clinical and academic careers. Please Note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. ____________________________________________________________________________ Role - The selected student will engage with interviewing and thematic analysis/qualitative coding. The student will also provide a comprehensive report that summarizes findings. ; IRB Status - IRB approved; Skills - Experience with semi-structured interviews is preferred but not required. | Hanna Barton, Scientist | hbarton@wisc.edu | Emergency Medicine | Post-Academic Detailing Interviews: Evaluating Impact and Improving Workflows | This project is part of the Emergency Care Systems Lab (ECSL), a transdisciplinary initiative at the forefront of advancing emergency care through innovative research and operational partnerships. The focus of this project is on conducting post-academic detailing interviews with providers who previously participated in academic detailing sessions. These interviews aim to evaluate the sessions' impact on provider understanding, confidence, and workflow integration of the Falls Risk Best Practice Alert (BPA) and referral process. The findings will inform improvements to academic detailing and BPA design, contributing to ECSL's mission of driving transformative healthcare solutions. This project offers an opportunity to contribute to cutting-edge research within the emergency care systems lab, evaluating the effects of an AI-driven intervention to improve public health. Students will gain hands-on experience in qualitative research, deepen their understanding of healthcare workflows and automated decision support, and develop skills applicable to both clinical and academic careers. Please Note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be onsite on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. | 1 | The selected student will engage with interviewing and thematic analysis/qualitative coding. The student will also provide a comprehensive report that summarizes findings. | Experience with semi-structured interviews is preferred but not required. | IRB approved | Yes | Yes | Yes | PhD students, UW undergraduates interested in research | No | No | Andrea Gilmore-Bykovskyi (algilmore@medicine.wisc.edu), Phoebe Natzke (pnatzke@medicine.wisc.edu) | Brian Patterson, bpatter@medicine.wisc.edu -- Co-Mentor: Hanna Barton, Scientist hbarton@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnud801aBva9xlcy2fWFWP7WB-lltO4A2N7AgBO6u5JgRx7kQtGeVjXCrSCFN60JBJ2w | ||||||||
| ayusodomingu@wisc.edu | Jose | Ayuso | PhD | Study of cell adoptive immunotherapies in organ-on-a-chip models | 6.084.242.754 | Dermatology | Not currently interested or available for Non-Shapiro research mentoring of medical students | Study of cell adoptive immunotherapies in organ-on-a-chip models: In this project we leverage advanced organ-on-a-chip platforms to study several aspects of cancer immunotherapy. We will focus on therapies based on the use of natural killer (NK) cells, which are part of the innate immune system and have cytotoxic capacity against malignant cells. NK cells will be isolated from blood samples and culture in the lab for further expansion and differentiation. Next, we will expose them to tumor cells (e.g., melanoma, squamous cell carcinoma, glioblastoma) to monitor their capacity to destroy tumor cells. We will evaluate multiple aspects of NK cell biology such as the capacity to establish a memory-like response, immune exhaustion, etc. ____________________________________________________________________________ Role - The student will use microfluidic and organ-on-a-chip devices to study critical aspects of cancer immunotherapy, with special emphasis on adoptive cell therapy. The candidate will work with different techniques related with immune cell isolation, cell culture, fluorescence microscopy, microdevice fabrication, engineering, and molecular biology. Using this approach, the student will monitor immune cell migration, cytotoxicity against tumor cells, or immune exhaustion in order to improve the capacity of the immune system to fight against solid tumors. Other aspects that the student can nurture are hypothesis formulation, data analysis, data presentation, and scientific writing. Our lab is a multidisciplinary and diverse group of engineers and biologists that work in close collaboration with multiple physicians across the UW-Madison to improve the translation of our studies into the clinic.; IRB Status - Approved; Skills - We will provide the traniing required, although experience in cell culture is appreciated. | Study of cell adoptive immunotherapies in organ-on-a-chip models | In this project we leverage advanced organ-on-a-chip platforms to study several aspects of cancer immunotherapy. We will focus on therapies based on the use of natural killer (NK) cells, which are part of the innate immune system and have cytotoxic capacity against malignant cells. NK cells will be isolated from blood samples and culture in the lab for further expansion and differentiation. Next, we will expose them to tumor cells (e.g., melanoma, squamous cell carcinoma, glioblastoma) to monitor their capacity to destroy tumor cells. We will evaluate multiple aspects of NK cell biology such as the capacity to establish a memory-like response, immune exhaustion, etc. | 0 | The student will use microfluidic and organ-on-a-chip devices to study critical aspects of cancer immunotherapy, with special emphasis on adoptive cell therapy. The candidate will work with different techniques related with immune cell isolation, cell culture, fluorescence microscopy, microdevice fabrication, engineering, and molecular biology. Using this approach, the student will monitor immune cell migration, cytotoxicity against tumor cells, or immune exhaustion in order to improve the capacity of the immune system to fight against solid tumors. Other aspects that the student can nurture are hypothesis formulation, data analysis, data presentation, and scientific writing. Our lab is a multidisciplinary and diverse group of engineers and biologists that work in close collaboration with multiple physicians across the UW-Madison to improve the translation of our studies into the clinic. | We will provide the traniing required, although experience in cell culture is appreciated. | Approved | Yes | Yes | Yes | PhD students | Yes | No | Mary Gannon (mgannon@dermatology.wisc.edu) | Jose Ayuso, ayusodomingu@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudaFrZ0ciPz8AHD2JG0AeiIHJHWSGg-Xpb_78gYy1YGDEyZRwMSHQuP5nwRIUBGW9A | ||||||||||
| rblanc@wisc.edu | Roméo | Blanc | PhD | Assistant Professor | Cell and Regenerative Biology | Not sure at the moment | Exploring the Systemic Influence of Bone Marrow Aging on Skeletal Muscle Function and Repair: Sarcopenia, the severe loss of muscle mass and function, affects nearly half of individuals over the age of 80, significantly impairing mobility and quality of life. This debilitating condition is caused by a decline in the activity of muscle stem cells (MuSCs). Recent evidence suggests that immune cells and proteins produced by bone marrow-resident hematopoietic stem cells (HSCs) play a significant role in driving this process. Our preliminary data reveal that chronic exposure to aged blood plasma accelerates the aging of skeletal muscle in mice, reducing both the function and the number of MuSCs. We hypothesize that age-related defects in HSCs contribute to muscle weakening by promoting systemic inflammation, which negatively affects MuSC activity. Unlike MuSCs, however, HSCs are more accessible to therapeutic interventions (i.e.:transplantation). Therefore, targeting aged HSCs or their derivatives could provide a new approach to mitigate age-related muscle decline and promote rejuvenation of aged muscle. While extensive research has been conducted on the aging of both HSCs and MuSCs, these studies have typically focused on each type of stem cell in isolation. This is a major gap, as aging involves significant crosstalk between various tissues, including the bone marrow and muscle. In this pilot study, we aim to bridge this gap by combining expertise in muscle aging and hematopoietic stem cells to explore the interaction between HSCs and MuSCs in aging and rejuvenation. Specifically, we will evaluate whether transplanting young bone marrow can improve muscle repair in aging mice by enhancing MuSC function. We will use an advanced ultra-low radiation method to perform bone marrow transplants with minimal inflammation and will monitor muscle aging and regeneration over time using non-invasive imaging techniques. By employing single-cell multi-omics analyses, we aim to uncover the mechanisms through which aging HSCs influence muscle decline, thereby enhancing our understanding of systemic aging, frailty, and sarcopenia. ____________________________________________________________________________ Role - Project Leader; IRB Status - N/A; Skills - Ideally has knowledge of immunology, flow cytometry, and not affraid to work with mice or blood. | Exploring the Systemic Influence of Bone Marrow Aging on Skeletal Muscle Function and Repair | Sarcopenia, the severe loss of muscle mass and function, affects nearly half of individuals over the age of 80, significantly impairing mobility and quality of life. This debilitating condition is caused by a decline in the activity of muscle stem cells (MuSCs). Recent evidence suggests that immune cells and proteins produced by bone marrow-resident hematopoietic stem cells (HSCs) play a significant role in driving this process. Our preliminary data reveal that chronic exposure to aged blood plasma accelerates the aging of skeletal muscle in mice, reducing both the function and the number of MuSCs. We hypothesize that age-related defects in HSCs contribute to muscle weakening by promoting systemic inflammation, which negatively affects MuSC activity. Unlike MuSCs, however, HSCs are more accessible to therapeutic interventions (i.e.:transplantation). Therefore, targeting aged HSCs or their derivatives could provide a new approach to mitigate age-related muscle decline and promote rejuvenation of aged muscle. While extensive research has been conducted on the aging of both HSCs and MuSCs, these studies have typically focused on each type of stem cell in isolation. This is a major gap, as aging involves significant crosstalk between various tissues, including the bone marrow and muscle. In this pilot study, we aim to bridge this gap by combining expertise in muscle aging and hematopoietic stem cells to explore the interaction between HSCs and MuSCs in aging and rejuvenation. Specifically, we will evaluate whether transplanting young bone marrow can improve muscle repair in aging mice by enhancing MuSC function. We will use an advanced ultra-low radiation method to perform bone marrow transplants with minimal inflammation and will monitor muscle aging and regeneration over time using non-invasive imaging techniques. By employing single-cell multi-omics analyses, we aim to uncover the mechanisms through which aging HSCs influence muscle decline, thereby enhancing our understanding of systemic aging, frailty, and sarcopenia. | 1 | Project Leader | While the candidate is expected to work toward independence, she/he will be assisted by the PI until feeling comfortable. | Ideally has knowledge of immunology, flow cytometry, and not affraid to work with mice or blood. | N/A | Yes | No (plan to use Dean's Office Funds) | Yes | PhD students | Unsure / Depends | Yes | N/A | Roméo Blanc, rblanc@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuf6D-OvKZP_y5NKt4kPWeHh7NtSEdDAlclqj1sILroMC3feFLCTm_OT7P_7A5mgGrM | ||||||||||
| ying.ge@wisc.edu | Ying | Ge | PhD | Vilas Distinguished Achievement Professor | 608 | Cell and Regenerative Biology | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Novel Omics approach for precision medicine and clinical diagnosis: “Omics” technologies offer transformative insights to elucidate disease mechanisms and are the enabling force for precision medicine. In the post-genomic era, proteomics is the next frontier allowing an in-depth understanding of the function of cellular systems in diseases. Unlike the genome, the proteome is dynamic and highly complex due to alternative splicing and post-translational modifications (PTMs). Top-down mass spectrometry (MS)-based proteomics is the most powerful technology to comprehensively characterize proteoforms that arise from genetic variations, alternative splicing, and PTMs. We have made major advances in top-down proteomics for analysis of intact proteins directly purified from heart tissue, blood, and human pluripotent stem cell-derived cardiomyocytes (hPSC). Recently, we have developed ultra-high-sensitivity top-down proteomics for analysis of single cells that captures single muscle cell heterogeneity in large proteoforms (>200 kDa). Importantly, we have linked altered cardiac proteoforms to contractile dysfunction in heart diseases using animal models and human clinical samples. Furthermore, we are harnessing the power of innovative top-down proteomics technologies with patient-specific hPSC-derived cardiomyocytes (CMs) in engineered cardiac tissue to understand proteoform biology in cardiac diseases for precision medicine. We have developed innovative technologies that can provide transformative insights into the understanding of cardiovascular disease and regeneration, to identify new molecular targets for diagnosis, and ultimately provide novel treatments for cardiovascular diseases. Our ultimate goal is to translate the bench discoveries to the clinic for precision medicine. Here are two ongoing NIH-funded projects that we are looking for MD students to work together with our PhD students in the lab toward precision medicine and clinical diagnosis. 1). Identify proteomic and metabolic markers in patients of ischemic cardiomyopathy. We will systematically analyze a large cohort of explanted failing hearts (both HFpEF and HPrEF) and compare to non-failing donor myocardium in both sexes. Proteomics and metabolic proteins as well as metabolites from human LV tissues will be analyzed by multi-omics. MD student will help link the omics data to clinical information. 2) Develop a comprehensive cardiac troponin assay for precision medicine. We will continue the development of a comprehensive and accurate proteoform-resolved clinical cTnI assay that can detect all cTnI proteoforms in blood for improved diagnosis of cardiovascular diseases. This will be built on the current successful collaboration between an MD student and PhD students. The current MD student has done a fantastic job and will graduate soon. So we are looking for a new MD student to continue this project. Ge group website: https://www.labs.wisc.edu/gelab/default.htm ____________________________________________________________________________ Role - The student is expected to 1) analyze clinical information; 2) work closely with other members in the group to integrate the clinical data with proteomics data, which will be used to for precision medicine and clinical diagnosis; IRB Status - Approved; Skills - Basic biochemistry and biology skills | Farhan Reza | fraza@medicine.wisc.edu | Medicine | Cardiology | Novel Omics approach for precision medicine and clinical diagnosis | “Omics” technologies offer transformative insights to elucidate disease mechanisms and are the enabling force for precision medicine. In the post-genomic era, proteomics is the next frontier allowing an in-depth understanding of the function of cellular systems in diseases. Unlike the genome, the proteome is dynamic and highly complex due to alternative splicing and post-translational modifications (PTMs). Top-down mass spectrometry (MS)-based proteomics is the most powerful technology to comprehensively characterize proteoforms that arise from genetic variations, alternative splicing, and PTMs. We have made major advances in top-down proteomics for analysis of intact proteins directly purified from heart tissue, blood, and human pluripotent stem cell-derived cardiomyocytes (hPSC). Recently, we have developed ultra-high-sensitivity top-down proteomics for analysis of single cells that captures single muscle cell heterogeneity in large proteoforms (>200 kDa). Importantly, we have linked altered cardiac proteoforms to contractile dysfunction in heart diseases using animal models and human clinical samples. Furthermore, we are harnessing the power of innovative top-down proteomics technologies with patient-specific hPSC-derived cardiomyocytes (CMs) in engineered cardiac tissue to understand proteoform biology in cardiac diseases for precision medicine. We have developed innovative technologies that can provide transformative insights into the understanding of cardiovascular disease and regeneration, to identify new molecular targets for diagnosis, and ultimately provide novel treatments for cardiovascular diseases. Our ultimate goal is to translate the bench discoveries to the clinic for precision medicine. Here are two ongoing NIH-funded projects that we are looking for MD students to work together with our PhD students in the lab toward precision medicine and clinical diagnosis. 1). Identify proteomic and metabolic markers in patients of ischemic cardiomyopathy. We will systematically analyze a large cohort of explanted failing hearts (both HFpEF and HPrEF) and compare to non-failing donor myocardium in both sexes. Proteomics and metabolic proteins as well as metabolites from human LV tissues will be analyzed by multi-omics. MD student will help link the omics data to clinical information. 2) Develop a comprehensive cardiac troponin assay for precision medicine. We will continue the development of a comprehensive and accurate proteoform-resolved clinical cTnI assay that can detect all cTnI proteoforms in blood for improved diagnosis of cardiovascular diseases. This will be built on the current successful collaboration between an MD student and PhD students. The current MD student has done a fantastic job and will graduate soon. So we are looking for a new MD student to continue this project. Ge group website: https://www.labs.wisc.edu/gelab/default.htm | 2 | The student is expected to 1) analyze clinical information; 2) work closely with other members in the group to integrate the clinical data with proteomics data, which will be used to for precision medicine and clinical diagnosis | MD students will work with senior members in the group | Basic biochemistry and biology skills | Approved | Yes | Yes | Yes | Not currently available to mentor other students | Unsure / Depends | Unsure / Depends | cdickey2@wisc.edu | Ying Ge, ying.ge@wisc.edu -- Co-Mentor: Farhan Reza fraza@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudpqim1Xx4N84iDVrPiI_-Q8RF-jwTZzPMtEM-4nKs-gRJlAziuS1JjzuILYcjEAkc | |||||
| henstenburg@wisc.edu | Jeffrey | Henstenburg | MD | Assistant Professor | 2.672.806.453 | Orthopedics and Rehabilitation | Shorter term projects, Looking for full time research coordinator if students interested in taking a gap year | Can standard scoliosis radiographs accurately predict pedicle size?: Knowing pedicle diameter is important for spine surgeons because it allows them to pick the proper size screw for optimal cortical bony purchase. This increases strength of the instrumentation construct and decreases rate of failure. In scoliosis surgery, we often don't have 3D imaging because we are looking at global deformity. Our question is simply, can we accurately predict pedicle size using standard 2-D films? Because most of our patients end up getting 3D imaging in the OR (or even before if they had an MRI) we can use these to compare to measurements on 2D films. ____________________________________________________________________________ Role - Data collection, measurements, analysis, background research and manuscript writing; IRB Status - N/A; Skills - Basic organization skills and understanding of spine deformity surgery (can be taught), basic manuscript writing skills | Pediatric Orthopedic Surgery | Ken Noonan | Can standard scoliosis radiographs accurately predict pedicle size? | Knowing pedicle diameter is important for spine surgeons because it allows them to pick the proper size screw for optimal cortical bony purchase. This increases strength of the instrumentation construct and decreases rate of failure. In scoliosis surgery, we often don't have 3D imaging because we are looking at global deformity. Our question is simply, can we accurately predict pedicle size using standard 2-D films? Because most of our patients end up getting 3D imaging in the OR (or even before if they had an MRI) we can use these to compare to measurements on 2D films. | 0 | Data collection, measurements, analysis, background research and manuscript writing | High | Basic organization skills and understanding of spine deformity surgery (can be taught), basic manuscript writing skills | N/A | No | Yes | Yes | DPT students, MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | No | N/A | Jeffrey Henstenburg, henstenburg@wisc.edu -- Co-Mentor: Ken Noonan | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufeiDoIlJqWEfBRKAkx2jh1hakcs1mn6S3VauaYV4iD1xBnzm7nhSDJeRDMxkqvaGs | |||||||
| noonan@ortho.wisc.edu | Ken | Noonan | MD | Professor | Orthopedics and Rehabilitation | Yes, case reports | Stick To It: A Randomized Control Trial Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting: Congenital Talipes Equinovarus (Clubfoot) is among the most common pediatric orthopedic conditions. It is a congenital deformity of the lower extremity that when untreated or improperly treated, can lead to severe dysfunction and disability. Fortunately, significant improvements in clubfoot management have occurred over time. In the late 20th century, Dr. Ignacio Ponseti's method of clubfoot manipulation and serial casting became the standard of care for initial management of clubfoot deformity around the globe. As part of the Ponseti method, patient's feet are manipulated and casted on a weekly basis to correct the components of the clubfoot. In order to attain proper correction, a well-fitting cast is needed. Placing a properly fitting cast takes significant effort on the part of the providers. Despite best efforts, sometimes even a well-molded cast can slip over the course of several days. When a patient's foot moves within a cast, pressure sores as well as malpositioning and deformity regression can ensue. In addition to causing harm to the patient, such complications can delay and/or deter treatment. Within the pediatric orthopedics department at the University of Wisconsin, we wish to determine if such complications can be lessened through the use of Mastisol application prior to cast placement. Mastisol is a liquid adhesive used to secure dressings for extended periods of time. In 2025, we wish to conduct a randomized controlled trial comparing outcomes as well as complication rates between individuals undergoing clubfoot casting with Mastisol application prior to cast placement versus those undergoing clubfoot casting without Mastisol prior to cast placement. ____________________________________________________________________________ Role - The student would play a primary role in study design, IRB submission and data collection. Additionally, this student would be able to shadow physicians in the orthopedic surgery clinic observing clubfoot management.; IRB Status - Will need to submit for IRB approval prior to onset.; Skills - Ideally, this student would have an interest in pediatric medicine and/or orthopedics. | Pediatric Orthopedics | Stick To It: A Randomized Control Trial Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting | Congenital Talipes Equinovarus (Clubfoot) is among the most common pediatric orthopedic conditions. It is a congenital deformity of the lower extremity that when untreated or improperly treated, can lead to severe dysfunction and disability. Fortunately, significant improvements in clubfoot management have occurred over time. In the late 20th century, Dr. Ignacio Ponseti's method of clubfoot manipulation and serial casting became the standard of care for initial management of clubfoot deformity around the globe. As part of the Ponseti method, patient's feet are manipulated and casted on a weekly basis to correct the components of the clubfoot. In order to attain proper correction, a well-fitting cast is needed. Placing a properly fitting cast takes significant effort on the part of the providers. Despite best efforts, sometimes even a well-molded cast can slip over the course of several days. When a patient's foot moves within a cast, pressure sores as well as malpositioning and deformity regression can ensue. In addition to causing harm to the patient, such complications can delay and/or deter treatment. Within the pediatric orthopedics department at the University of Wisconsin, we wish to determine if such complications can be lessened through the use of Mastisol application prior to cast placement. Mastisol is a liquid adhesive used to secure dressings for extended periods of time. In 2025, we wish to conduct a randomized controlled trial comparing outcomes as well as complication rates between individuals undergoing clubfoot casting with Mastisol application prior to cast placement versus those undergoing clubfoot casting without Mastisol prior to cast placement. | 1 | The student would play a primary role in study design, IRB submission and data collection. Additionally, this student would be able to shadow physicians in the orthopedic surgery clinic observing clubfoot management. | Ideally, this student would have an interest in pediatric medicine and/or orthopedics. | Will need to submit for IRB approval prior to onset. | No NIH Funding | Department of Orthopedics | Yes | Not currently available to mentor other students | No | Yes | Peter Li MD, PhD (Attending Pediatric Orthopedic Surgeon), Lindsey Boyke MD, MPH (Attending Pediatric Orthopedist), Patrick Touhy, MD, MS (Fellow), and Brianna Davidson (Cast Technician) | Ken Noonan, noonan@ortho.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufhKvRSkB3DJstzSPsFTWgrLlI2JxD565optnlrT5tK7R96EQ_EdGGQOSew086WcME | ||||||||||
| Henstenburg@wisc.edu | Jeffrey | Henstenburg | MD | Assistant Professor | 2.672.806.453 | Orthopedics and Rehabilitation | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity, Looking for full time paid research coordinator for students looking to take a gap year | Orthopedic Injury Patterns in Pregnancy: The goal of this project is to characterize orthopedic injury patters in pregnant patients. This will be accomplished through an IRB approved retrospective chart review of patients in our department that came to us with a new orthopedic injury (fracture, ligamentous injury, bitch injury) while they were pregnant. My hypothesis is that there is a pattern of injuries seen in pregnancy due to physiologic changes that occur during pregnancy, most importantly hyperplasticity. Are there higher rates of cervical spine injuries? How about elbow dislocations? Will be interesting to see what we find. ____________________________________________________________________________ Role - Chart review and data collection, analysis, manuscript writing; IRB Status - Not yet obtained; Skills - Basic organization and manuscript writing skillls | Pediatric Orthopedic Surgery | Ken Noonan | Orthopedic Injury Patterns in Pregnancy | The goal of this project is to characterize orthopedic injury patters in pregnant patients. This will be accomplished through an IRB approved retrospective chart review of patients in our department that came to us with a new orthopedic injury (fracture, ligamentous injury, bitch injury) while they were pregnant. My hypothesis is that there is a pattern of injuries seen in pregnancy due to physiologic changes that occur during pregnancy, most importantly hyperplasticity. Are there higher rates of cervical spine injuries? How about elbow dislocations? Will be interesting to see what we find. | 0 | Chart review and data collection, analysis, manuscript writing | High | Basic organization and manuscript writing skillls | Not yet obtained | No | Yes | Yes | DPT students, MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | Yes | N/A | Jeffrey Henstenburg, Henstenburg@wisc.edu -- Co-Mentor: Ken Noonan | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufOyi1Rd2KwnWMrQyz5nKLiKuiLGW-P_-Ho4jyDdcSqm4t8nCYPhaw_XhVNGF9WvbA | |||||||
| nsandbo@medicine.wisc.edu | Nathan | Sandbo | MD | Dr. | 608 | Medicine | Shorter term projects, Research Electives for credit | Determining the mechanisms by which coculturing human macrophages with established human lung fibroblasts acts to polarize macrophages towards a profibrotic phenotype to better understand the development of pulmonary fibrosis. : Pulmonary Fibrosis is a disease of excessive lung scarring caused by aberrant extracellular matrix (ECM) assembly by lung fibroblasts. Lung fibroblasts can be differentiated towards a more ECM producing fibroblast, termed myofibroblasts, in many known and yet unknown ways. There is proven cross talk between lung macrophages and lung fibroblasts that can exacerbate the differentiation towards the profibrotic myofibroblast, yet the mechanisms remain elusive, and it is not clear if fibroblast phenotype can influence macrophage polarization. We have discovered that when macrophages are cocultured on established human lung fibroblasts, macrophages become polarized to a profibrotic phenotype that is found in human lung fibrosis. We hypothesize that these interactions can create a circular feedback loop between macrophages and fibroblasts during lung fibrosis. For this project, the student would utilize our existing and well established coculture model system with the human macrophage cell line THP-1 cells and primary human lung fibroblasts. The interested student would investigate whether this interaction depends on a soluble factor from the macrophages to the fibroblasts and/or whether this interaction was dependent on cell-cell contact between the macrophages and the fibroblasts. To determine whether a soluble factor is involved, the macrophages and fibroblasts would be cocultured in a Transwell system where the cell media is shared but macrophage and fibroblast cell contact is prevented. In addition, fibroblasts would be incubated with conditioned media from macrophages to determine if a factor from macrophages is sufficient to promote a fibrotic phenotype in the fibroblasts (and the reverse: conditioned media from fibroblasts exposed to macrophages). Alternatively, to determine if the cell-cell interaction is necessary, the macrophages will be cocultured with fibroblasts with molecular tools (antibody blocking and siRNA) to modulate this cell-cell interaction to determine whether this interaction is necessary or sufficient to polarize macrophages towards a profibrotic phenotype. In the process of performing this work, the student will generate data leading to an abstract and poster for presentation at the DOM Research Day as well as presenting their data at the annual American Thoracic Society Conference. This research will allow the student to learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment. ____________________________________________________________________________ Role - The student will learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment.; IRB Status - Exempt; Skills - Minimal | Allergy, Pulmonary and Critical Care | Determining the mechanisms by which coculturing human macrophages with established human lung fibroblasts acts to polarize macrophages towards a profibrotic phenotype to better understand the development of pulmonary fibrosis. | Pulmonary Fibrosis is a disease of excessive lung scarring caused by aberrant extracellular matrix (ECM) assembly by lung fibroblasts. Lung fibroblasts can be differentiated towards a more ECM producing fibroblast, termed myofibroblasts, in many known and yet unknown ways. There is proven cross talk between lung macrophages and lung fibroblasts that can exacerbate the differentiation towards the profibrotic myofibroblast, yet the mechanisms remain elusive, and it is not clear if fibroblast phenotype can influence macrophage polarization. We have discovered that when macrophages are cocultured on established human lung fibroblasts, macrophages become polarized to a profibrotic phenotype that is found in human lung fibrosis. We hypothesize that these interactions can create a circular feedback loop between macrophages and fibroblasts during lung fibrosis. For this project, the student would utilize our existing and well established coculture model system with the human macrophage cell line THP-1 cells and primary human lung fibroblasts. The interested student would investigate whether this interaction depends on a soluble factor from the macrophages to the fibroblasts and/or whether this interaction was dependent on cell-cell contact between the macrophages and the fibroblasts. To determine whether a soluble factor is involved, the macrophages and fibroblasts would be cocultured in a Transwell system where the cell media is shared but macrophage and fibroblast cell contact is prevented. In addition, fibroblasts would be incubated with conditioned media from macrophages to determine if a factor from macrophages is sufficient to promote a fibrotic phenotype in the fibroblasts (and the reverse: conditioned media from fibroblasts exposed to macrophages). Alternatively, to determine if the cell-cell interaction is necessary, the macrophages will be cocultured with fibroblasts with molecular tools (antibody blocking and siRNA) to modulate this cell-cell interaction to determine whether this interaction is necessary or sufficient to polarize macrophages towards a profibrotic phenotype. In the process of performing this work, the student will generate data leading to an abstract and poster for presentation at the DOM Research Day as well as presenting their data at the annual American Thoracic Society Conference. This research will allow the student to learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment. | 0 | The student will learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment. | Minimal | Minimal | Exempt | Yes | Yes | Yes | MPH students, PhD students, UW undergraduates interested in research | No | No | Angie Tebon Oler | Nathan Sandbo, nsandbo@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueUV3pAQs16seSJD5c4r6UugE5kVXU9QGpzHqo_cBVnaxkDHsoZcudiY1dYL97owbE | ||||||||
| nsandbo@medicine.wisc.edu | Nathan | Sandbo | MD | Dr. | 608 | Medicine | Shorter term projects | Elucidating the mechanisms by which enzymes of the Hexosamine Biosynthetic Pathway play a role in the development of Pulmonary Fibrosis: Pulmonary Fibrosis is a disease of excessive lung scarring caused by aberrant extracellular matrix (ECM) assembly by lung fibroblasts. ECM is a complex system of macromolecules, produced and modulated by a myriad of enzymes within the fibroblasts. Fibroblasts, when differentiated into myofibroblasts, have a robust profibrotic phenotype. The Hexosamine Biosynthetic Pathway (HBP) is a nutrient sensing, glucose repurposing, pathway made up of enzymes involved in the differentiation of myofibroblasts, as well as the regulation and production of ECM macromolecules. The HBP is essential for the production of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a vital component of N- linked and O-linked glycosylation, which are posttranslational modifications of proteins, many that are known to play a role in the regulation of ECM. We have found that there is elevated expression of key enzymes of the HBP (such as glutamine fructose-6-phosphate transaminase 2 (GFPT2)) in human lung fibrosis (Idiopathic pulmonary fibrosis) and mouse models of lung fibrosis. Additionally, we have found that modulating the enzyme glutamine fructose-6-phosphate transaminase 2 (GFPT2) impacts the expression of fibronectin, a prominent marker of lung fibrosis. GFPT2 is a rate limiting enzyme of the HBP and differences in expression directly impact the function of the HBP. Thus, we hypothesize that the HBP is essential for the development of lung fibrosis. For this project, the student would study GFPT2 and other prospective enzymes in the HBP in cell culture and ex vivo tissue models of lung fibrosis and assist with investigations using the in vivo models of lung fibrosis. By way of short hairpin RNA (shRNA) lentivirus, GFPT2 can be attenuated in both human lung fibroblast cell culture (in vitro) and human precision cut lung slices (PCLS – ex vivo). In addition, we have in hand a GFPT2 global and conditional knockout mouse, for investigating the role of GFPT2 in the bleomycin-induced mouse model of fibrosis (in vivo). The impact that reduction of GFPT2 will have on both the fibroblast to myofibroblast differentiation as well as the ECM architecture will be measured. In the process of performing this work, the student will generate data leading to an abstract and poster for presentation at the DOM Research Day as well as presenting their data at the annual American Thoracic Society Conference. This research will allow the student to learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, human and mouse tissue handling and processing, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment. ____________________________________________________________________________ Role - The student will learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, human and mouse tissue handling and processing, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment.; IRB Status - exempt; Skills - minimal | Allergy, Pulmonary and Critical Care | Elucidating the mechanisms by which enzymes of the Hexosamine Biosynthetic Pathway play a role in the development of Pulmonary Fibrosis | Pulmonary Fibrosis is a disease of excessive lung scarring caused by aberrant extracellular matrix (ECM) assembly by lung fibroblasts. ECM is a complex system of macromolecules, produced and modulated by a myriad of enzymes within the fibroblasts. Fibroblasts, when differentiated into myofibroblasts, have a robust profibrotic phenotype. The Hexosamine Biosynthetic Pathway (HBP) is a nutrient sensing, glucose repurposing, pathway made up of enzymes involved in the differentiation of myofibroblasts, as well as the regulation and production of ECM macromolecules. The HBP is essential for the production of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a vital component of N- linked and O-linked glycosylation, which are posttranslational modifications of proteins, many that are known to play a role in the regulation of ECM. We have found that there is elevated expression of key enzymes of the HBP (such as glutamine fructose-6-phosphate transaminase 2 (GFPT2)) in human lung fibrosis (Idiopathic pulmonary fibrosis) and mouse models of lung fibrosis. Additionally, we have found that modulating the enzyme glutamine fructose-6-phosphate transaminase 2 (GFPT2) impacts the expression of fibronectin, a prominent marker of lung fibrosis. GFPT2 is a rate limiting enzyme of the HBP and differences in expression directly impact the function of the HBP. Thus, we hypothesize that the HBP is essential for the development of lung fibrosis. For this project, the student would study GFPT2 and other prospective enzymes in the HBP in cell culture and ex vivo tissue models of lung fibrosis and assist with investigations using the in vivo models of lung fibrosis. By way of short hairpin RNA (shRNA) lentivirus, GFPT2 can be attenuated in both human lung fibroblast cell culture (in vitro) and human precision cut lung slices (PCLS – ex vivo). In addition, we have in hand a GFPT2 global and conditional knockout mouse, for investigating the role of GFPT2 in the bleomycin-induced mouse model of fibrosis (in vivo). The impact that reduction of GFPT2 will have on both the fibroblast to myofibroblast differentiation as well as the ECM architecture will be measured. In the process of performing this work, the student will generate data leading to an abstract and poster for presentation at the DOM Research Day as well as presenting their data at the annual American Thoracic Society Conference. This research will allow the student to learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, human and mouse tissue handling and processing, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment. | 0 | The student will learn important basic science technical, data analysis, and scientific presentation skills including but not limited to: hypothesis generation/testing, tissue culture procedures, human and mouse tissue handling and processing, RNA and protein isolation, quantitative real-time PCR, SDS Page/western blotting, immunocytochemistry, data analysis, data presentation, and scientific communication/writing. The student will be supported by full-time research staff/faculty and pursue this project in a team-science environment. | minimal | minimal | exempt | Yes | Yes | Yes | PhD students, UW undergraduates interested in research | No | No | Angie Tebon Oler aoler@medicine.wisc.edu | Nathan Sandbo, nsandbo@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucBjXxMrq8DQ3ZxJvP379oHM0OHMiCKhgS85t9hCBGIA3dexO8SKkOvvHU5YKYqhXc | ||||||||
| dlamming@medicine.wisc.edu | Dudley | Lamming | PhD | Associate Professor | Medicine | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | DIetary protein quality as a regulator of metabolic health and aging: Our research focuses on understanding how branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—affect metabolism, aging, and overall health. Elevated BCAA levels are strongly associated with obesity and insulin resistance in humans, and this can be seen in multiple animal models as well. Our work has explored how reducing dietary BCAA intake can improve metabolic health and potentially extend lifespan. More broadly, our results suggest that both the quantity and quality - the specific amino acid composition – of dietary protein influences both metabolic health and longevity. In one of our key studies, we demonstrated that lowering dietary BCAAs by two-thirds in mice significantly improved metabolic health, including better body composition and enhanced blood glucose control. Notably, this dietary intervention extends the lifespan of male mice by 30% and reduced frailty, though we observed that the same benefits were not seen in female mice. We identified isoleucine as the critical BCAA. When we reduced dietary isoleucine in mice, the results were striking - mice showed rapid improvements in metabolic health, including weight loss and enhanced insulin sensitivity, suggesting that lowering dietary isoleucine could be a promising approach to treating and preventing obesity and diabetes. Isoleucine restriction alone increases lifespan in both sexes. Students will work with the PI to design a study focused on aspects of this problem they are interested in, and work one on one with a lab member to execute the project over the summer, analyze their data, and publish it. https://lamminglab.medicine.wisc.edu/ ____________________________________________________________________________ Role - Student will help design the project based on their research interests and be primarily responsible for executing the project under the guidance of a senior lab member.; IRB Status - N/A; Skills - None, we will train you | Endocrinology, Diabetes and Metabolism | DIetary protein quality as a regulator of metabolic health and aging | Our research focuses on understanding how branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—affect metabolism, aging, and overall health. Elevated BCAA levels are strongly associated with obesity and insulin resistance in humans, and this can be seen in multiple animal models as well. Our work has explored how reducing dietary BCAA intake can improve metabolic health and potentially extend lifespan. More broadly, our results suggest that both the quantity and quality - the specific amino acid composition – of dietary protein influences both metabolic health and longevity. In one of our key studies, we demonstrated that lowering dietary BCAAs by two-thirds in mice significantly improved metabolic health, including better body composition and enhanced blood glucose control. Notably, this dietary intervention extends the lifespan of male mice by 30% and reduced frailty, though we observed that the same benefits were not seen in female mice. We identified isoleucine as the critical BCAA. When we reduced dietary isoleucine in mice, the results were striking - mice showed rapid improvements in metabolic health, including weight loss and enhanced insulin sensitivity, suggesting that lowering dietary isoleucine could be a promising approach to treating and preventing obesity and diabetes. Isoleucine restriction alone increases lifespan in both sexes. Students will work with the PI to design a study focused on aspects of this problem they are interested in, and work one on one with a lab member to execute the project over the summer, analyze their data, and publish it. https://lamminglab.medicine.wisc.edu/ | 1 | Student will help design the project based on their research interests and be primarily responsible for executing the project under the guidance of a senior lab member. | Medium | None, we will train you | N/A | Yes | DOM matches Shapiro funding | Yes | RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | No | N/A | Dudley Lamming, dlamming@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudjwy2vGM_vQTfLS2WoPChFKKZDaDVOLnAXN98pMD48x1YpQotE6I-h3PQACue-Aqc | |||||||||
| mgannon@dermatology.wisc.edu | Sarah | Korger | MD | Assistant Professor (CHS) | Dermatology | Mentoring opportunities, clinic shadowing opportunities | Reassessing Health Beliefs and Skin Cancer Prevention Practices Among Wisconsin Dairy Farmers: A 30-Year Follow-Up: Three decades ago, Marlenga (1995) explored the health beliefs and skin cancer prevention practices of Wisconsin dairy farmers, highlighting the importance of sun protection and the influence of occupational exposures on health behaviors. Given the evolving understanding of skin cancer and advancements in prevention strategies and information dissemination, this study aims to reassess these beliefs and practices among the same population. Objectives: 1. To evaluate current health beliefs regarding skin cancer among Wisconsin dairy farmers. 2. To analyze changes in skin cancer prevention practices over the past 30 years. 3. To identify factors influencing these beliefs and practices in the contemporary context. Methodology: • Participants: Wisconsin dairy farmers, with a focus on both long-term farmers and newer entrants to the profession. • Design: A mixed-methods approach, incorporating quantitative surveys and qualitative interviews. • Data Collection: Surveys will assess knowledge of skin cancer risks, beliefs about prevention, and current protective practices. Follow-up interviews will provide deeper insights into individual experiences and motivations. • Analysis: Quantitative data will be analyzed using statistical software to identify trends over time, while thematic analysis will be applied to qualitative data. Expected Outcomes: This study anticipates revealing shifts in health beliefs and practices due to increased awareness of skin cancer risks and the influence of modern educational campaigns. It aims to identify persistent barriers to effective skin cancer prevention and provide recommendations for targeted interventions in the dairy farming community. Significance: By comparing findings from this study with those of Marlenga (1995), we can better understand the progression of health beliefs and prevention strategies in agricultural settings. This research will contribute to the development of more effective health promotion programs tailored to the unique needs of dairy farmers, ultimately enhancing occupational health and safety. ____________________________________________________________________________ Role - Submit an IRB, create a quantitative and qualitative survey, identify the study participants, assist in the analysis the survey data, write a research letter for publication, and present on findings at Dermatology Grand Rounds. ; IRB Status - Needs approval, will be straightforward to obtain; Skills - None | Reassessing Health Beliefs and Skin Cancer Prevention Practices Among Wisconsin Dairy Farmers: A 30-Year Follow-Up | Three decades ago, Marlenga (1995) explored the health beliefs and skin cancer prevention practices of Wisconsin dairy farmers, highlighting the importance of sun protection and the influence of occupational exposures on health behaviors. Given the evolving understanding of skin cancer and advancements in prevention strategies and information dissemination, this study aims to reassess these beliefs and practices among the same population. Objectives: 1. To evaluate current health beliefs regarding skin cancer among Wisconsin dairy farmers. 2. To analyze changes in skin cancer prevention practices over the past 30 years. 3. To identify factors influencing these beliefs and practices in the contemporary context. Methodology: • Participants: Wisconsin dairy farmers, with a focus on both long-term farmers and newer entrants to the profession. • Design: A mixed-methods approach, incorporating quantitative surveys and qualitative interviews. • Data Collection: Surveys will assess knowledge of skin cancer risks, beliefs about prevention, and current protective practices. Follow-up interviews will provide deeper insights into individual experiences and motivations. • Analysis: Quantitative data will be analyzed using statistical software to identify trends over time, while thematic analysis will be applied to qualitative data. Expected Outcomes: This study anticipates revealing shifts in health beliefs and practices due to increased awareness of skin cancer risks and the influence of modern educational campaigns. It aims to identify persistent barriers to effective skin cancer prevention and provide recommendations for targeted interventions in the dairy farming community. Significance: By comparing findings from this study with those of Marlenga (1995), we can better understand the progression of health beliefs and prevention strategies in agricultural settings. This research will contribute to the development of more effective health promotion programs tailored to the unique needs of dairy farmers, ultimately enhancing occupational health and safety. | 0 | Submit an IRB, create a quantitative and qualitative survey, identify the study participants, assist in the analysis the survey data, write a research letter for publication, and present on findings at Dermatology Grand Rounds. | None | Needs approval, will be straightforward to obtain | No | Yes | Yes | Not currently available to mentor other students | No | Yes | Mary Gannon, mgannon@dermatology.wisc.edu | Sarah Korger, mgannon@dermatology.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudaJr2ZuWKl_vb4Reny1pKicnkA7l-nVjrnfbHFzQ72tGwv7-NDzqaVlgPUXFLaNX0 | |||||||||||
| boyettanders@wisc.edu | Jesse | Boyett Anderson | MD | Assistant Professor | 0 | Pediatrics | Not currently interested or available for Non-Shapiro research mentoring of medical students | Infrastructure for Managing Critical Congenital Heart Defects at Wisconsin Birthing Hospitals: One of every 100 babies in Wisconsin is born with a heart defect. Some of these babies need specialized medical care as soon as they are born. As of 2019, there were approximately 105 hospitals in Wisconsin that delivered babies. It is unclear how many of them have the equipment and expertise to manage an infant with a complex congenital heart defect or how far a woman would need to travel to access such care for her baby. In 2010, fewer than half of delivery hospitals in Wisconsin stocked the lifesaving cardiac medication, alprostadil, and only about a third had the ability to obtain a neonatal echocardiogram. We propose to survey delivery facilities in the state of Wisconsin regarding their preparation to evaluate and manage a newborn with a critical congenital heart defect. Specifically, we plan to ask whether they stock alprostadil or have the ability to obtain a neonatal echocardiogram and also describe their access to neonatology, pediatric cardiology, or pediatric cardiothoracic surgery and their strategies for the transport of a critically ill neonate. https://www.pediatrics.wisc.edu/research/research-groups/hokanson/ ____________________________________________________________________________ Role - Collaborate on survey creation and administration (winter/spring), directly contact non-responding hospitals (summer), analyze data (summer), submit data to the Midwest Pediatric Cardiology Society meeting in September and other formats such as the Wisconsin Association for Perinatal Care. The student would also write up a manuscript for submission to a journal such as Congenital Heart Disease, Cardiology in the Young, or the Wisconsin Medical Journal (summer/fall).; IRB Status - will likely be exempt, student can participate in the process; Skills - critical thinking, ability to synthesize journal articles, willingness to learn statistical and qualitative analysis skills, ability to incorporate constructive feedback, ability to call medical professionals | Pediatric Cardiology | John Hokanson, MD, Professor | jhokanson@wisc.edu | Pediatrics | pediatric cardiology | Infrastructure for Managing Critical Congenital Heart Defects at Wisconsin Birthing Hospitals | One of every 100 babies in Wisconsin is born with a heart defect. Some of these babies need specialized medical care as soon as they are born. As of 2019, there were approximately 105 hospitals in Wisconsin that delivered babies. It is unclear how many of them have the equipment and expertise to manage an infant with a complex congenital heart defect or how far a woman would need to travel to access such care for her baby. In 2010, fewer than half of delivery hospitals in Wisconsin stocked the lifesaving cardiac medication, alprostadil, and only about a third had the ability to obtain a neonatal echocardiogram. We propose to survey delivery facilities in the state of Wisconsin regarding their preparation to evaluate and manage a newborn with a critical congenital heart defect. Specifically, we plan to ask whether they stock alprostadil or have the ability to obtain a neonatal echocardiogram and also describe their access to neonatology, pediatric cardiology, or pediatric cardiothoracic surgery and their strategies for the transport of a critically ill neonate. https://www.pediatrics.wisc.edu/research/research-groups/hokanson/ | 0 | Collaborate on survey creation and administration (winter/spring), directly contact non-responding hospitals (summer), analyze data (summer), submit data to the Midwest Pediatric Cardiology Society meeting in September and other formats such as the Wisconsin Association for Perinatal Care. The student would also write up a manuscript for submission to a journal such as Congenital Heart Disease, Cardiology in the Young, or the Wisconsin Medical Journal (summer/fall). | moderate | critical thinking, ability to synthesize journal articles, willingness to learn statistical and qualitative analysis skills, ability to incorporate constructive feedback, ability to call medical professionals | will likely be exempt, student can participate in the process | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Yes | Becca Evans (revans7@wisc.edu); Andrea Miller (andrea.miller@pediatrics.wisc.edu) | Jesse Boyett Anderson, boyettanders@wisc.edu -- Co-Mentor: John Hokanson, MD, Professor jhokanson@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuetZBmEu9YPyEDsS8NG2_Tx4x7XoYh2qwTS4v4JB4jAVMtbg6ltNqXlIhU8ung4pho | ||||
| coleary@wisc.edu | Claire | O'Leary | PhD | Assistant Professor | Pediatrics | I am interested in mentoring a yearlong student but do not have space in the lab in 2024. | Feasibility of low input proteomics for understanding rare cell functional heterogeneity ex vivo: My lab is interested in how the mucosal tissues in the GI tract adapt to changing environments, including microbial exposure. We focus on tuft cells, rare secretory epithelial cells, as critical sentinels shaping barrier function and tissue immunity throughout the GI. In this project, we will test the feasibility of using mass spectrometry for proteomic analysis of rare cells, like tuft cells, which will require optimization of low input techniques. After establishing feasibility we will sort tuft cells from different GI tissues to determine if protein expression is altered in tissue specific ways. ____________________________________________________________________________ Role - dissecting mice, isolating cells, preparing cells for sorting; IRB Status - N/A; Skills - willing to learn mouse dissection, prior experience in a wet lab | Allergy, Immunology & Rheumatology | Feasibility of low input proteomics for understanding rare cell functional heterogeneity ex vivo | My lab is interested in how the mucosal tissues in the GI tract adapt to changing environments, including microbial exposure. We focus on tuft cells, rare secretory epithelial cells, as critical sentinels shaping barrier function and tissue immunity throughout the GI. In this project, we will test the feasibility of using mass spectrometry for proteomic analysis of rare cells, like tuft cells, which will require optimization of low input techniques. After establishing feasibility we will sort tuft cells from different GI tissues to determine if protein expression is altered in tissue specific ways. | 1 | dissecting mice, isolating cells, preparing cells for sorting | moderate | willing to learn mouse dissection, prior experience in a wet lab | N/A | Yes | Yes | Yes | PhD students | No | No | Kelsey Scholtens kscholtens@pediatrics.wisc.edu Gillie Yanoff yanoff@wisc.edu Maureen Maletta maletta@wisc.edu Theresa Compton trcompton@wisc.edu | Claire O'Leary, coleary@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudZij4UxoIwRoULaQXVYzIATKUF_vXsdj8qbr2fVOyvacfU34TiaCCqeYBYExWVPHw | |||||||||
| mspulia@medicine.wisc.edu | Michael | Pulia | MD PhD | Associate Professor | Emergency Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Characterizing Resiliency in Antimicrobial Stewardship Programs During the COVID-19 Pandemic : The COVID-19 pandemic stressed antimicrobial stewardship (AMS) programs with increased workloads and lack of guidance on the treatment of COVID-19. Throughout the pandemic, COVID-19 patients have received antibiotics for this viral illness despite reported low rates of confirmed bacterial co-infections. Over the last year we have conducted 35 semi-structured interviews with pharmacists, infectious disease physicians and other quality leaders from health systems across the country. We sought to characterize why some antimicrobial stewardship programs were more resilient during the COVID-19 pandemic while others were not. All interviews have been completed, transcribed and a first pass at coding is complete. This project will be a secondary analysis using existing data. Based on our data, we have identified some research questions that could be of interest: • challenges and strategies to antibiotic stewardship for patients with COVID-19 • characterizing the lived-experience of working in antimicrobial stewardship during the COVID-19 pandemic • utility of procalcitonin in AMS We are excited to partner with the Shapiro student to develop a qualitative research question that is of interest to them. https://emed.wisc.edu/research/emergency-care-infectious-diseases/ ____________________________________________________________________________ Role - We are excited for a Shapiro student to assist with developing a research question that is interesting to them and within the scope of the data, analyzing the data and drafting an initial abstract and manuscript. Long-term the student will have the option to revise the manuscript and submit and present the abstract at a National Meeting. Please note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be on site on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. Vacations or travel are allowable but need to be discussed/approved before the start of the program. ; IRB Status - Approved; Skills - Prior qualitative experience is preferred but not required | Characterizing Resiliency in Antimicrobial Stewardship Programs During the COVID-19 Pandemic | The COVID-19 pandemic stressed antimicrobial stewardship (AMS) programs with increased workloads and lack of guidance on the treatment of COVID-19. Throughout the pandemic, COVID-19 patients have received antibiotics for this viral illness despite reported low rates of confirmed bacterial co-infections. Over the last year we have conducted 35 semi-structured interviews with pharmacists, infectious disease physicians and other quality leaders from health systems across the country. We sought to characterize why some antimicrobial stewardship programs were more resilient during the COVID-19 pandemic while others were not. All interviews have been completed, transcribed and a first pass at coding is complete. This project will be a secondary analysis using existing data. Based on our data, we have identified some research questions that could be of interest: • challenges and strategies to antibiotic stewardship for patients with COVID-19 • characterizing the lived-experience of working in antimicrobial stewardship during the COVID-19 pandemic • utility of procalcitonin in AMS We are excited to partner with the Shapiro student to develop a qualitative research question that is of interest to them. https://emed.wisc.edu/research/emergency-care-infectious-diseases/ | 0 | We are excited for a Shapiro student to assist with developing a research question that is interesting to them and within the scope of the data, analyzing the data and drafting an initial abstract and manuscript. Long-term the student will have the option to revise the manuscript and submit and present the abstract at a National Meeting. Please note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be on site on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. Vacations or travel are allowable but need to be discussed/approved before the start of the program. | Moderate | Prior qualitative experience is preferred but not required | Approved | Yes | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, UW undergraduates interested in research | No | No | Becky Schwei rschwei@medicine.wisc.edu, Phoebe Natzke pnatzke@medicine.wisc.edu | Michael Pulia, mspulia@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudy-WJxV5JvPojamJbvNokOB8knByJDH2xaUgGCOQSbIpEkeZzNGwhgKfLZ_y88Qsk | ||||||||||
| rwoods@uwhealth.org | Ryan | Woods | MD, MPH | Associate Professor of Radiology | 6.084.699.313 | Radiology | Shorter term projects, Research Electives for credit | Understanding how Radiologists Utilize the Electronic Health Record: This project revolves around understanding how Radiologists utilize the electronic health record in their day to day. We will be analyzing a data set which catalogues the different portions of the record that radiologists use. ____________________________________________________________________________ Role - Data collection, analysis. Abstract/manuscript preparation. ; IRB Status - Approved; Skills - Nothing specific | Breast Imaging | Medicine | Clinical Informatics | Understanding how Radiologists Utilize the Electronic Health Record | This project revolves around understanding how Radiologists utilize the electronic health record in their day to day. We will be analyzing a data set which catalogues the different portions of the record that radiologists use. | 0 | Data collection, analysis. Abstract/manuscript preparation. | Moderate | Nothing specific | Approved | No | Yes | Yes | Not currently available to mentor other students | No | No | Max Olin (molin@uwhealth.org) | Ryan Woods, rwoods@uwhealth.org -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufJ0mYYCwnF6Dneoqih7iO3h4a4Z2o4sAyOeNNRzEfDz_7qLHHKtV6V175HEBSD9vY | ||||||
| mspulia@medicine.wisc.edu | Michael | Pulia | MD PhD | Associate Professor | Emergency Medicine | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Evaluating Antibiotic Prescribing for Acute Respiratory Tract Infections in the Emergency Department : Patients with acute respiratory tract infections, which are predominately viral, are often given unnecessary antibiotics due to diagnostic uncertainty regarding the presence of bacterial infection. The appropriate use of antibiotics is a globally accepted public health priority given the link between high utilization rates and prevalence of resistant bacterial infections. We have collected weekly surveillance data on respiratory viral testing (COVID-19, influenza, RSV, etc.), antibiotic prescriptions, culture results, and a variety of other variables (demographics, vitals, comorbidities, lab test results, etc.) for patients seen in the UW Health emergency departments for acute respiratory tract infections from November 2021 to present. We will work with the Shapiro student to develop a research question they are interested in answering with this dataset. Examples of potential studies include: (1) trends in antibiotic prescribing by viral pathogen, (2) predictors for receiving antibiotics, and (3) trends in antibiotic resistance. https://emed.wisc.edu/research/emergency-care-infectious-diseases/ ____________________________________________________________________________ Role - We are excited for a Shapiro student to assist with developing a research question that is interesting to them and within the scope of the data, analyzing the data using statistical software (e.g. R), and drafting an initial abstract and manuscript. Long-term the student will have the option to revise the manuscript and submit and present the abstract at a National Meeting. Please note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be on site on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. Vacations or travel are allowable but need to be discussed/approved before the start of the program. ; IRB Status - Approved; Skills - A student with programming experience is highly preferred so that a full analysis can be completed during the Shapiro experience. | Evaluating Antibiotic Prescribing for Acute Respiratory Tract Infections in the Emergency Department | Patients with acute respiratory tract infections, which are predominately viral, are often given unnecessary antibiotics due to diagnostic uncertainty regarding the presence of bacterial infection. The appropriate use of antibiotics is a globally accepted public health priority given the link between high utilization rates and prevalence of resistant bacterial infections. We have collected weekly surveillance data on respiratory viral testing (COVID-19, influenza, RSV, etc.), antibiotic prescriptions, culture results, and a variety of other variables (demographics, vitals, comorbidities, lab test results, etc.) for patients seen in the UW Health emergency departments for acute respiratory tract infections from November 2021 to present. We will work with the Shapiro student to develop a research question they are interested in answering with this dataset. Examples of potential studies include: (1) trends in antibiotic prescribing by viral pathogen, (2) predictors for receiving antibiotics, and (3) trends in antibiotic resistance. https://emed.wisc.edu/research/emergency-care-infectious-diseases/ | 0 | We are excited for a Shapiro student to assist with developing a research question that is interesting to them and within the scope of the data, analyzing the data using statistical software (e.g. R), and drafting an initial abstract and manuscript. Long-term the student will have the option to revise the manuscript and submit and present the abstract at a National Meeting. Please note: Shapiro students participating in a project with a faculty mentor from the Dept of Emergency Medicine are expected to be on site on Tuesdays for 2-3 hours. This time is spent attending EM Research Committee meetings and didactic learning sessions. Individual faculty mentors may communicate additional on-site requirements depending on the needs of the project. Vacations or travel are allowable but need to be discussed/approved before the start of the program. | Moderate/High | A student with programming experience is highly preferred so that a full analysis can be completed during the Shapiro experience. | Approved | Yes | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, UW undergraduates interested in research | No | No | Becky Schwei rschwei@medicine.wisc.edu, Phoebe Natzke pnatzke@medicine.wisc.edu | Michael Pulia, mspulia@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufrkbzDaFkd8jeVUR-nuUstJp5mByoAzCqjveodVqAPvR9yhIvy8FXTUYG0VCmqkPg | ||||||||||
| mliu@medicine.wisc.edu | Monica | Liu | MD, PhD | Instructor | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Patient-Derived Organoid Models of Acute Lung Transplant Rejection: Our overarching goal is to uncover and manipulate mechanisms of inflammatory and fibrosing lung disease using patients' own cells. Current projects are focused on lung transplant rejection, which limits patients' survival and quality of life after transplant. We developed techniques to grow patients’ cells outside the body, generating small spheres of cells called organoids, which mimic the function of the lung. This means we can now take samples of cells from the lungs of transplant recipients and compare organoids from patients with and without rejection. This is a new way of investigating how rejection damages the transplanted lung, which may eventually lead to new treatments. These organoid techniques also need to be further developed and validated so that they can be applied to other lung diseases, potentially offering tools for personalized medicine. (https://www.medicine.wisc.edu/directory/liu_monica-yun) ____________________________________________________________________________ Role - Co-develop the project with Dr. Liu by doing background reading, asking questions, and bringing your own ideas. Perform hands-on lab work: process patient samples, culture human cells, analyze lung cell types, etc. Acquire and analyze data for presentation and hopefully eventual co-author publication.; IRB Status - Approved; Skills - Curiosity, enthusiasm, and attention to detail! We can tailor the project to your skills and interests. | Pulmonary and Critical Care | Patient-Derived Organoid Models of Acute Lung Transplant Rejection | Our overarching goal is to uncover and manipulate mechanisms of inflammatory and fibrosing lung disease using patients' own cells. Current projects are focused on lung transplant rejection, which limits patients' survival and quality of life after transplant. We developed techniques to grow patients’ cells outside the body, generating small spheres of cells called organoids, which mimic the function of the lung. This means we can now take samples of cells from the lungs of transplant recipients and compare organoids from patients with and without rejection. This is a new way of investigating how rejection damages the transplanted lung, which may eventually lead to new treatments. These organoid techniques also need to be further developed and validated so that they can be applied to other lung diseases, potentially offering tools for personalized medicine. (https://www.medicine.wisc.edu/directory/liu_monica-yun) | 1 | Co-develop the project with Dr. Liu by doing background reading, asking questions, and bringing your own ideas. Perform hands-on lab work: process patient samples, culture human cells, analyze lung cell types, etc. Acquire and analyze data for presentation and hopefully eventual co-author publication. | Hands-on training will be provided, and you will be encouraged to develop increasing independence. | Curiosity, enthusiasm, and attention to detail! We can tailor the project to your skills and interests. | Approved | No | Yes | Yes | PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | No | N/A | Monica Liu, mliu@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuftz_AOQXqkYHJcTp8BlUc66Pe3SfgWn3om-NNehsLJuJMfjqbPjg0UMbZBsf8cyZ0 | |||||||||
| hkloster@wisc.edu | Heidi | Kloster | MD | Associate Professor, Department of Pediatrics, Associate Program Director, Pediatrics Residency Program | 510 | Pediatrics | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Children with Serious and Complex Illness- Improving Hospital and Home Care for Children and their Families: Our student would be engaged in research across one or more of two existing projects, based on interest and experience: 1. Family LENS (Lived Experience in Scholarship): Education Curricular innovation in which caregiver stories are recorded and used in education and research to increase awareness of the family perspective of caring for children with medical complexity. During summer of 2025 we will be carrying out a qualitative methods analysis of the interviews. 2. Wisconsin Policy for In-Home Care: policy review and intervention development for WI policy related to professional in-home care for children with medical complexity. ____________________________________________________________________________ Role - Literature review; data entry and analysis; participate in team meetings; learn qualitative research methods; leadership and potential for authorship on publications based on level and comfort of student. Opportunity for clinical shadowing based on student interest.; IRB Status - Approved; Skills - Comfort with office suite (excel, word), ability to carry out literature review in collaboration with faculty and librarians, enthusiasm for observing and potentially coding interviews with caregivers | Hospital Medicine and Complex Care | Mary Ehlenbach, MD Associate Professor, Department of Pediatrics, Medical Director, Pediatric Complex Care | mehlenbach@pediatrics.wisc.edu | Pediatrics | Hospital Medicine and Complex Care | Children with Serious and Complex Illness- Improving Hospital and Home Care for Children and their Families | Our student would be engaged in research across one or more of two existing projects, based on interest and experience: 1. Family LENS (Lived Experience in Scholarship): Education Curricular innovation in which caregiver stories are recorded and used in education and research to increase awareness of the family perspective of caring for children with medical complexity. During summer of 2025 we will be carrying out a qualitative methods analysis of the interviews. 2. Wisconsin Policy for In-Home Care: policy review and intervention development for WI policy related to professional in-home care for children with medical complexity. | 2 | Literature review; data entry and analysis; participate in team meetings; learn qualitative research methods; leadership and potential for authorship on publications based on level and comfort of student. Opportunity for clinical shadowing based on student interest. | Self-directed day-to-day, but regular oversight and access to mentors and project staff | Comfort with office suite (excel, word), ability to carry out literature review in collaboration with faculty and librarians, enthusiasm for observing and potentially coding interviews with caregivers | Approved | Yes | Possibly (dependent on extension of current ICTR funding) | Yes | Not currently available to mentor other students | Yes | Yes | N/A | Heidi Kloster, hkloster@wisc.edu -- Co-Mentor: Mary Ehlenbach, MD Associate Professor, Department of Pediatrics, Medical Director, Pediatric Complex Care mehlenbach@pediatrics.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufqVZIUjLWRc9LF-eRlJuB8EyDBIf8dwPrJG-NMk81uRd-WkDEfy0M8RJZ0vAL_gFQ | ||||
| 01/08/2025 | richards@urology.wisc.edu | Kyle | Richards | MD FACS | Associate Professor | 6.089.603.337 | Urology | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Health services research in bladder and prostate cancer: https://urology.wisc.edu/blog/staff/richards-md-facs-kyle-a/ I have worked with 1 student every summer the past 10 years. My goal is to introduce them to urology as a field, come to the operating room to see world class robotic surgeries, and help move a research project forward. The research is tailored to the students goals, but in general, my research involves using health services research techniques including artificial intelligence and machine learning to find better treatments and provide better care for patients with bladder or prostate cancer. ____________________________________________________________________________ Role - Collect some data, help with analysis, put together tables and figures, learn about basic bio stats, and write abstract/paper.; IRB Status - Approved; Skills - None | Urologic Oncology | Health services research in bladder and prostate cancer | https://urology.wisc.edu/blog/staff/richards-md-facs-kyle-a/ I have worked with 1 student every summer the past 10 years. My goal is to introduce them to urology as a field, come to the operating room to see world class robotic surgeries, and help move a research project forward. The research is tailored to the students goals, but in general, my research involves using health services research techniques including artificial intelligence and machine learning to find better treatments and provide better care for patients with bladder or prostate cancer. | 0 | Collect some data, help with analysis, put together tables and figures, learn about basic bio stats, and write abstract/paper. | Moderate | None | Approved | No | Yes | Yes | Not currently available to mentor other students | No | Yes | Denise Mussehl "mussehl@urology.wisc.edu" and Anna Peacock peacock@urology.wisc.edu | Kyle Richards, richards@urology.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuc_5VhoDMSm5Xk-c9OfUOZi3Zm1aHm7ptQ1ar5szy0mWEr4yB38wpX_FgHZXG9cAbQ | |||||||
| 01/08/2025 | spiker@ortho.wisc.edu | Andrea | Spiker | M.D. | Assistant Prof, Director Hip Preservation Program, Director Sports Medicine Fellowship | 608 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | The Relationship between Hip Abductor Pathology and outcomes after Hip Preservation and Abductor Repair Surgery: We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a collaborative project with radiology. This is a retrospective review of all patients who have undergone hip arthroscopy, periacetabular osteotomy and/or abductor repair surgery. Our question relates to whether abductor pathology noted on pre-operative magnetic resonance imaging is correlated with patient reported outcomes after surgery. Every hip arthroscopy patient undergoes an MRI study prior to surgery. We will classify abductor (gluteus medius and gluteus minimus pathology) on pre-operative MRI using the Blankenbaker-Spiker Abductor (BSAb) classification system, which was developed here at the University of Wisconsin. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy, as well as abductor repair surgery) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. ____________________________________________________________________________ Role - A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. ; IRB Status - We have IRB approval for our registry and this project falls under our IRB umbrella protocol; Skills - Excel and Word. Organizational skills and good communication with the other members of the team. | Sports Medicine | Other | Hip Preservation | Haley Smith | hsmith@ortho.wisc.edu | Orthopedics and Rehabilitation | Sports Medicine | The Relationship between Hip Abductor Pathology and outcomes after Hip Preservation and Abductor Repair Surgery | We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a collaborative project with radiology. This is a retrospective review of all patients who have undergone hip arthroscopy, periacetabular osteotomy and/or abductor repair surgery. Our question relates to whether abductor pathology noted on pre-operative magnetic resonance imaging is correlated with patient reported outcomes after surgery. Every hip arthroscopy patient undergoes an MRI study prior to surgery. We will classify abductor (gluteus medius and gluteus minimus pathology) on pre-operative MRI using the Blankenbaker-Spiker Abductor (BSAb) classification system, which was developed here at the University of Wisconsin. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy, as well as abductor repair surgery) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. | 0 | A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. | Moderate - We will give specific instructions and direction, but the student will need to be self-motivated to complete the project and make the most out of the experience. | Excel and Word. Organizational skills and good communication with the other members of the team. | We have IRB approval for our registry and this project falls under our IRB umbrella protocol | Yes | Yes | Yes | Not currently available to mentor other students | No | No | Heidi Ableidinger (Ableidinger@ortho.wisc.edu) Orthopedics Student Services Coordinator; Amie Armstrong (armstrong@ortho.wisc.edu) Hip Preservation Research Coordinator | Andrea Spiker, spiker@ortho.wisc.edu -- Co-Mentor: Haley Smith hsmith@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucoKIWcGNwDjMV7LFHfKZcT81ORsU3d0RwPOvthjJAaLx32zJQfVcwwWzUDUnyiLHc | |
| cjc@medicine.wisc.edu | Chris | Crnich | Md, PhD | Professor of Medicine, Division of Infectious Diseases | 0 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Structure and Process of Infection Prevention Among Nursing Homes Participating in a Public Health Response Network: The Crnich lab and its collaborating nursing homes in Wisconsin are currently engaged in a Nursing Home Public Health Response Network (NH PHRN) that is funded by Centers for Disease Control and Prevention (CDC). The CDC NH NHPRN conducts real-time surveillance of infectious diseases and analyses of healthcare facility operations to inform public health policies and guidance around infection prevention practices in nursing homes. The Crnich lab is responsible for overseeing collection of data on the physical (building-related) and operational (staffing, policies, and practices) characteristics of the nursing homes participating in the CDC NH PHRN, including the infection prevention and control strategies these facilities employ to control COVID-19 and other infectious diseases. More information on the Crnich Research Team can be found at https://www.medicine.wisc.edu/infectious-disease/crnich-research ____________________________________________________________________________ Role - Interested students will help members of the Crnich lab analyze data collected from nursing homes participating in the CDC NH PHRN to characterize changes to infection prevention practices among participating facilities since the COVID-19 public health emergency ended. Familiarity with how to perform basic descriptive statistical analyses (e.g., means, standard deviation, etc.) is desirable. Candidates will be expected to participate in authorship of a peer-reviewed manuscript. ; IRB Status - Approved; Skills - Basic Data analysis (using Microsoft Excel, understanding means, standard deviation), writing. | Infectious Disease | Shane Fernando | Shane.Fernando@abtglobal.com | Structure and Process of Infection Prevention Among Nursing Homes Participating in a Public Health Response Network | The Crnich lab and its collaborating nursing homes in Wisconsin are currently engaged in a Nursing Home Public Health Response Network (NH PHRN) that is funded by Centers for Disease Control and Prevention (CDC). The CDC NH NHPRN conducts real-time surveillance of infectious diseases and analyses of healthcare facility operations to inform public health policies and guidance around infection prevention practices in nursing homes. The Crnich lab is responsible for overseeing collection of data on the physical (building-related) and operational (staffing, policies, and practices) characteristics of the nursing homes participating in the CDC NH PHRN, including the infection prevention and control strategies these facilities employ to control COVID-19 and other infectious diseases. More information on the Crnich Research Team can be found at https://www.medicine.wisc.edu/infectious-disease/crnich-research | 1 | Interested students will help members of the Crnich lab analyze data collected from nursing homes participating in the CDC NH PHRN to characterize changes to infection prevention practices among participating facilities since the COVID-19 public health emergency ended. Familiarity with how to perform basic descriptive statistical analyses (e.g., means, standard deviation, etc.) is desirable. Candidates will be expected to participate in authorship of a peer-reviewed manuscript. | Independent with oversight. | Basic Data analysis (using Microsoft Excel, understanding means, standard deviation), writing. | Approved | Yes | No (plan to use Dean's Office Funds) | Yes | MPH students | No | Yes | kwagman@medicine.wisc.edu | Chris Crnich, cjc@medicine.wisc.edu -- Co-Mentor: Shane Fernando Shane.Fernando@abtglobal.com | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufTc4WzBF9Gj-bht7axZCcYfmBiC1SqDcjx6MsgXFtnRfOfqiMmlk6xfUHjeL_cIoo | ||||||
| 01/08/2025 | spiker@ortho.wisc.edu | Andrea | Spiker | M.D. | Assistant Prof, Director Hip Preservation Program, Director Sports Medicine Fellowship | 608 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | The Workup and Post-operative Outcomes of Hip Preservation Patients Who Present with Atypical Pain: We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. We will identify those patients who present with “typical” hip pain (anterior groin, activity related) versus “atypical” (lateral, posterior, radiating, constant) hip pain. We will then analyze the differences in these groups related to the work up (how many clinic visits before surgery, how many diagnostic injections before surgery, etc), description of pain upon presentation, provocative maneuvers that were positive, intra-operative findings, post-operative course including patient reported outcomes. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. ____________________________________________________________________________ Role - A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. ; IRB Status - We have IRB approval for our registry and this project falls under our IRB umbrella protocol; Skills - Excel and Word. Organizational skills and good communication with the other members of the team. | Sports Medicine | Other | Hip Preservation | Haley Smith | hsmith@ortho.wisc.edu | Orthopedics and Rehabilitation | Sports Medicine | The Workup and Post-operative Outcomes of Hip Preservation Patients Who Present with Atypical Pain | We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. We will identify those patients who present with “typical” hip pain (anterior groin, activity related) versus “atypical” (lateral, posterior, radiating, constant) hip pain. We will then analyze the differences in these groups related to the work up (how many clinic visits before surgery, how many diagnostic injections before surgery, etc), description of pain upon presentation, provocative maneuvers that were positive, intra-operative findings, post-operative course including patient reported outcomes. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. | 0 | A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. | Moderate - We will give specific instructions and direction, but the student will need to be self-motivated to complete the project and make the most out of the experience. | Excel and Word. Organizational skills and good communication with the other members of the team. | We have IRB approval for our registry and this project falls under our IRB umbrella protocol | Yes | Yes | Yes | Not currently available to mentor other students | No | No | Heidi Ableidinger (Ableidinger@ortho.wisc.edu) Orthopedics Student Services Coordinator; Amie Armstrong (armstrong@ortho.wisc.edu) Hip Preservation Research Coordinator | Andrea Spiker, spiker@ortho.wisc.edu -- Co-Mentor: Haley Smith hsmith@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuekQnkptao5jYFMFNcPeZS6r4xN9lmLcZ6pTWtaDMH2fPiPzQkPBdW9W6FSSdFIebE | |
| cjc@medicine.wisc.edu | Chris | Crnich | Md, PhD | Professor of Medicine, Division of Infectious Diseases | 0 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Characterization of Nursing Homes Participating in a Public Health Response Network: The Crnich lab and its collaborating nursing homes in Wisconsin are currently engaged in a Nursing Home Public Health Response Network (NH PHRN) that is funded by Centers for Disease Control and Prevention (CDC). The CDC NH NHPRN conducts real-time surveillance of infectious diseases and analyses of healthcare facility operations to inform public health policies and guidance around infection prevention practices in nursing homes. The Crnich lab is responsible for overseeing collection of data on the physical (building-related) and operational (staffing, policies, and practices) characteristics of the nursing homes participating in the CDC NH PHRN, including the infection prevention and control strategies these facilities employ to control COVID-19 and other infectious diseases. More information on the Crnich Research Team can be found at https://www.medicine.wisc.edu/infectious-disease/crnich-research ____________________________________________________________________________ Role - Interested students will help members of the Crnich lab analyze data collected to characterize the nursing homes participating in the CDC NH PHRN (e.g., size, staffing, long-term care services provided, etc.). Familiarity with how to perform basic descriptive statistical analyses (e.g., means, standard deviation, etc.) is desirable. Candidates will be expected to participate in authorship of a peer-reviewed manuscript. ; IRB Status - Approved; Skills - Basic Data analysis (using Microsoft Excel, understanding means, standard deviation), writing. | Infectious Disease | Shane Fernando | Shane.Fernando@abtglobal.com | Characterization of Nursing Homes Participating in a Public Health Response Network | The Crnich lab and its collaborating nursing homes in Wisconsin are currently engaged in a Nursing Home Public Health Response Network (NH PHRN) that is funded by Centers for Disease Control and Prevention (CDC). The CDC NH NHPRN conducts real-time surveillance of infectious diseases and analyses of healthcare facility operations to inform public health policies and guidance around infection prevention practices in nursing homes. The Crnich lab is responsible for overseeing collection of data on the physical (building-related) and operational (staffing, policies, and practices) characteristics of the nursing homes participating in the CDC NH PHRN, including the infection prevention and control strategies these facilities employ to control COVID-19 and other infectious diseases. More information on the Crnich Research Team can be found at https://www.medicine.wisc.edu/infectious-disease/crnich-research | 1 | Interested students will help members of the Crnich lab analyze data collected to characterize the nursing homes participating in the CDC NH PHRN (e.g., size, staffing, long-term care services provided, etc.). Familiarity with how to perform basic descriptive statistical analyses (e.g., means, standard deviation, etc.) is desirable. Candidates will be expected to participate in authorship of a peer-reviewed manuscript. | Independent with oversight. | Basic Data analysis (using Microsoft Excel, understanding means, standard deviation), writing. | Approved | Yes | No (plan to use Dean's Office Funds) | Yes | MPH students | No | Yes | kwagman@medicine.wisc.edu | Chris Crnich, cjc@medicine.wisc.edu -- Co-Mentor: Shane Fernando Shane.Fernando@abtglobal.com | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufk6WeCs6IknXmyUWoIAedgpuc3K5_efsBPgHxTQItb0F8gpV5zE3QBf67o9tCliXM | ||||||
| 01/08/2025 | spiker@ortho.wisc.edu | Andrea | Spiker | M.D. | Assistant Prof, Director Hip Preservation Program, Director Sports Medicine Fellowship | 608 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | Profiling Femoroacetabular Impingement Patients’ Sports Participation and Specific Positions: We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. As standard of care, patients are asked to complete patient reported outcome measures (PROMs) pre-operatively, along with an intake form describing sports participation throughout their lifetime and specific details of which sports they participated in. We will evaluate this data to determine which sports are most prevalent in our patient population, and then within those sports, which positions are most frequently associated with the diagnosis of femoroacetabular impingement or dysplasia requiring hip preservation surgery. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My surgeon co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. ____________________________________________________________________________ Role - A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Joachim or Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. ; IRB Status - We have IRB approval for our registry and this project falls under our IRB umbrella protocol; Skills - Excel and Word. Organizational skills and good communication with the other members of the team. | Sports Medicine | Orthopedics and Rehabilitation | Hip Preservation | Mikel Joachim, PhD & Haley Smith, MD | joachim@ortho.wisc.edu, hsmith@ortho.wisc.edu | Orthopedics and Rehabilitation | Sports Medicine | Profiling Femoroacetabular Impingement Patients’ Sports Participation and Specific Positions | We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. As standard of care, patients are asked to complete patient reported outcome measures (PROMs) pre-operatively, along with an intake form describing sports participation throughout their lifetime and specific details of which sports they participated in. We will evaluate this data to determine which sports are most prevalent in our patient population, and then within those sports, which positions are most frequently associated with the diagnosis of femoroacetabular impingement or dysplasia requiring hip preservation surgery. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My surgeon co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. | 0 | A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Joachim or Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. | Moderate - We will give specific instructions and direction, but the student will need to be self-motivated to complete the project and make the most out of the experience. | Excel and Word. Organizational skills and good communication with the other members of the team. | We have IRB approval for our registry and this project falls under our IRB umbrella protocol | Yes | Yes | Yes | Not currently available to mentor other students | No | No | Heidi Ableidinger (Ableidinger@ortho.wisc.edu) Orthopedics Student Services Coordinator; Amie Armstrong (armstrong@ortho.wisc.edu) Hip Preservation Research Coordinator | Andrea Spiker, spiker@ortho.wisc.edu -- Co-Mentor: Mikel Joachim, PhD & Haley Smith, MD joachim@ortho.wisc.edu, hsmith@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnue_l4CQnR9j60x9STvkWFYhyB13uz5j4x4hXRax6CqsEFftmMQunX4J2B2Xt7McV9k | |
| 01/08/2025 | spiker@ortho.wisc.edu | Andrea | Spiker | M.D. | Assistant Prof, Director Hip Preservation Program, Director Sports Medicine Fellowship | 608 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | Patient Factors Related to Patient Reported Outcome Survey Completion and Clinic Follow-up Compliance: We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. As standard of care, patients are asked to complete patient reported outcome measures (PROMs) pre-operatively, and at multiple time points post-operatively. We hope to understand the factors related to whether patients are compliant in completing their PROs. We hypothesize that patients who are doing well after surgery will be less likely to complete their PROs. Those with a higher ADI (patients who live in an area with greater deprivation) may also be less likely to complete PROs. We also want to identify patient characteristics, including patient demographics, geographic location of residence (including area of deprivation index), preoperative findings, surgical characteristics, and patient reported outcomes, and how these relate to compliance with recommended clinic follow-up. Our standard follow up is as follows: 2 weeks, 6 weeks, 3 months, 1 year post-operative. We hypothesize that patients who are doing very well early after recovery will fail to follow up as requested, and those who live further away are less likely to follow up in person and will utilize video follow-up options. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. ____________________________________________________________________________ Role - A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. ; IRB Status - We have IRB approval for our registry and this project falls under our IRB umbrella protocol; Skills - Excel and Word. Organizational skills and good communication with the other members of the team. | Sports Medicine | Orthopedics and Rehabilitation | Hip Preservation | Haley Smith, MD | hsmith@ortho.wisc.edu | Orthopedics and Rehabilitation | Sports Medicine | Patient Factors Related to Patient Reported Outcome Survey Completion and Clinic Follow-up Compliance | We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. As standard of care, patients are asked to complete patient reported outcome measures (PROMs) pre-operatively, and at multiple time points post-operatively. We hope to understand the factors related to whether patients are compliant in completing their PROs. We hypothesize that patients who are doing well after surgery will be less likely to complete their PROs. Those with a higher ADI (patients who live in an area with greater deprivation) may also be less likely to complete PROs. We also want to identify patient characteristics, including patient demographics, geographic location of residence (including area of deprivation index), preoperative findings, surgical characteristics, and patient reported outcomes, and how these relate to compliance with recommended clinic follow-up. Our standard follow up is as follows: 2 weeks, 6 weeks, 3 months, 1 year post-operative. We hypothesize that patients who are doing very well early after recovery will fail to follow up as requested, and those who live further away are less likely to follow up in person and will utilize video follow-up options. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. | 0 | A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. | Moderate - We will give specific instructions and direction, but the student will need to be self-motivated to complete the project and make the most out of the experience. | Excel and Word. Organizational skills and good communication with the other members of the team. | We have IRB approval for our registry and this project falls under our IRB umbrella protocol | Yes | Yes | Yes | Not currently available to mentor other students | No | Yes | Heidi Ableidinger (Ableidinger@ortho.wisc.edu) Orthopedics Student Services Coordinator; Amie Armstrong (armstrong@ortho.wisc.edu) Hip Preservation Research Coordinator | Andrea Spiker, spiker@ortho.wisc.edu -- Co-Mentor: Haley Smith, MD hsmith@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudDpKwzbWdF03kQ8MGcxk9nplRinIkxllfYqh_-auuZi99-xvKKPj4hTka7xBhHPKA | |
| funk@surgery.wisc.edu | Luke | Funk | MD, MPH | Professor of Surgery | 608 | Surgery | Shorter term projects, Research Electives for credit | Association Between Anticoagulation Treatment Strategy and Bleeding/DVT After Bariatric Surgery: The project is a retrospective analysis using the UW Bariatric Surgery Database. It involves data extraction of bariatric surgery patients at UW and entry into the RedCap UW bariatric surgery database. The analysis will involve descriptive statistics and regression modeling. ____________________________________________________________________________ Role - Data extraction from the electronic health record and entry into the UW bariatric surgery database, assistance in project management and working with data analysts to interpret study findings; IRB Status - IRB has been completed; Skills - General knowledge and interest in the field of bariatric surgery | Minimally Invasive and Bariatric Surgery | Association Between Anticoagulation Treatment Strategy and Bleeding/DVT After Bariatric Surgery | The project is a retrospective analysis using the UW Bariatric Surgery Database. It involves data extraction of bariatric surgery patients at UW and entry into the RedCap UW bariatric surgery database. The analysis will involve descriptive statistics and regression modeling. | 0 | Data extraction from the electronic health record and entry into the UW bariatric surgery database, assistance in project management and working with data analysts to interpret study findings | Moderate; there are other researchers/students who will be available for on-boarding and training | General knowledge and interest in the field of bariatric surgery | IRB has been completed | Yes | Not sure what the stipend cost is. I would inquire about the Dean's Office Funds first I think. | Yes | UW undergraduates interested in research | No | Yes | Christine Williams williams@surgery.wisc.edu | Luke Funk, funk@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudv3ubwppSfcIrN-w59h3XK5wpYh7qenmeeWBtTr4Xpm_nOi-NOvisEoGJq5FrBBnQ | ||||||||
| huy.dinh@wisc.edu | Huy | Dinh | PhD | Assistant Professor | Oncology | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Single-cell and spatial analysis of myeloid cells in inflammation and cancers: Our lab is interested in using single-cell and spatial approaches to understand the heterogeneity and plasticity of myeloid cells in cancer and inflammation. In this project, students will have opportunities to learn and apply computational approaches with these high-dimensional data across species and disease conditions. ____________________________________________________________________________ Role - Learn and analyze single-cell and spatial omics data under PI and a senior grad student or postdoc's supervision; IRB Status - N/A; Skills - basic programming needed | Biostatistics and Medical Informatics | possible senior grad student or postdoc, depend on specific projects | Single-cell and spatial analysis of myeloid cells in inflammation and cancers | Our lab is interested in using single-cell and spatial approaches to understand the heterogeneity and plasticity of myeloid cells in cancer and inflammation. In this project, students will have opportunities to learn and apply computational approaches with these high-dimensional data across species and disease conditions. | 2 | Learn and analyze single-cell and spatial omics data under PI and a senior grad student or postdoc's supervision | basic programming needed | N/A | Yes | No (plan to use Dean's Office Funds) | Yes | PhD students, UW undergraduates interested in research | No | No | N/A | Huy Dinh, huy.dinh@wisc.edu -- Co-Mentor: possible senior grad student or postdoc, depend on specific projects | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueMr6EvAe0q7Up-D4u_Qn6ThQTDqMUH-uNbxi4FuO_t7O0nqPUdvZAwDFzR6oPjLIg | |||||||||
| watson@ortho.wisc.edu | Andrew | Watson | MD, MS | Associate Professor | 0 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | Youth soccer athlete mental health and injury prevention program: One of the research areas in The Human Performance Laboratory is conducting research on identifying the mental health and injury risk of elite youth soccer athletes. We collect mental and physical health and quality of life survey data twice a year, and are using the data to improve athlete mental health and to lower injury risk. The Shapiro students will be working on this project with the research team, and will be involved with all aspects of the study. ____________________________________________________________________________ Role - Data collection, data analysis, manuscript preparation; IRB Status - Approved; Skills - Excel and writing skills | Sports medicine | Kristin Haraldsdottir, associate scientist | haraldsdottir@ortho.wisc.edu | Orthopedics and Rehabilitation | Youth soccer athlete mental health and injury prevention program | One of the research areas in The Human Performance Laboratory is conducting research on identifying the mental health and injury risk of elite youth soccer athletes. We collect mental and physical health and quality of life survey data twice a year, and are using the data to improve athlete mental health and to lower injury risk. The Shapiro students will be working on this project with the research team, and will be involved with all aspects of the study. | 0 | Data collection, data analysis, manuscript preparation | High | Excel and writing skills | Approved | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | No | Liana Nash, nash@ortho.wisc.edu | Andrew Watson, watson@ortho.wisc.edu -- Co-Mentor: Kristin Haraldsdottir, associate scientist haraldsdottir@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudw_P_YxfSSM0UlIidVjANS1uJjKxZFlH1VXbyIIH6bHQDqIsuK3VJ1MXt1i24KZXU | |||||
| jdenson@wisc.edu | Jill | Denson | PhD, MSSW, APSW | Research Assistant Professor; Director UWPRC | Pediatrics | Shorter term projects | Father and family perspectives on adapting an evidence-based program for remote blood pressure monitoring in Black pregnant people: The mission of the UWPRC (https://prc.wisc.edu) is to improve the health of women and birthing people, infants, and families impacted by health inequities by conducting and building capacity for high-quality applied health promotion and disease prevention research rooted in health equity. The Core Research Project (CRP) of the UWPRC, Adaptation of Staying Healthy After Childbirth (STAC) to Prevent and Reduce Racial Disparities in Postpartum Morbidity and Mortality, seeks to improve access to the Staying healthy After Childbirth program (STAC) for Black women and birthing people in Wisconsin. The evidence-based STAC program is designed to monitor blood pressure during pregnancy and after birth by providing pregnant and postpartum people with home monitoring blood pressure kits that sends daily blood pressure readings to an individual’s healthcare team. The CRP is working with the CRP’s STAC Community Advisory Board, UWPRC Community Advisory Board, UWPRC Translational Partners Panel, and healthcare organizations to culturally adapt, refine and implement STAC to provide remote pregnancy support and blood pressure care in community-based organizations serving diverse communities of Black women and birthing people throughout the state, such as doula organizations and public health departments. In adapting the STAC model, it is important to include fathers and other family members of the pregnant person. Health outcomes often span multiple generations and include paternal genetic linkage. Therefore, a generational approach including fathers is needed to address maternal and infant outcomes and chronic disease prevention. Due to discrimination and medical mistrust, African Americans depend on their extended kinship networks for health-related information. These informal methods of passing information from generation to generation have many purposes and should be integrated in health communication strategies while addressing health disparities. We intend on conducting group concept mapping (GCM) sessions over the summer to elicit father and family member perspectives on the STAC adaptation. GCM is a participatory mixed-method research design and integrates qualitative processes such as focus group-like sessions with multi-variate analysis, in order to capture ideas generated from participants lived experience. ____________________________________________________________________________ Role - Students are expected to contribute to recruitment, data collection, data analysis, write-up of results; IRB Status - We will obtain approval before the Shapiro project would start; Skills - Mixed methods research experience is helpful but not required. We will provide training on group concept mapping. | GPAM | Father and family perspectives on adapting an evidence-based program for remote blood pressure monitoring in Black pregnant people | The mission of the UWPRC (https://prc.wisc.edu) is to improve the health of women and birthing people, infants, and families impacted by health inequities by conducting and building capacity for high-quality applied health promotion and disease prevention research rooted in health equity. The Core Research Project (CRP) of the UWPRC, Adaptation of Staying Healthy After Childbirth (STAC) to Prevent and Reduce Racial Disparities in Postpartum Morbidity and Mortality, seeks to improve access to the Staying healthy After Childbirth program (STAC) for Black women and birthing people in Wisconsin. The evidence-based STAC program is designed to monitor blood pressure during pregnancy and after birth by providing pregnant and postpartum people with home monitoring blood pressure kits that sends daily blood pressure readings to an individual’s healthcare team. The CRP is working with the CRP’s STAC Community Advisory Board, UWPRC Community Advisory Board, UWPRC Translational Partners Panel, and healthcare organizations to culturally adapt, refine and implement STAC to provide remote pregnancy support and blood pressure care in community-based organizations serving diverse communities of Black women and birthing people throughout the state, such as doula organizations and public health departments. In adapting the STAC model, it is important to include fathers and other family members of the pregnant person. Health outcomes often span multiple generations and include paternal genetic linkage. Therefore, a generational approach including fathers is needed to address maternal and infant outcomes and chronic disease prevention. Due to discrimination and medical mistrust, African Americans depend on their extended kinship networks for health-related information. These informal methods of passing information from generation to generation have many purposes and should be integrated in health communication strategies while addressing health disparities. We intend on conducting group concept mapping (GCM) sessions over the summer to elicit father and family member perspectives on the STAC adaptation. GCM is a participatory mixed-method research design and integrates qualitative processes such as focus group-like sessions with multi-variate analysis, in order to capture ideas generated from participants lived experience. | 0 | Students are expected to contribute to recruitment, data collection, data analysis, write-up of results | Mixed methods research experience is helpful but not required. We will provide training on group concept mapping. | We will obtain approval before the Shapiro project would start | Yes | No (plan to use Dean's Office Funds) | Yes | MPH students | No | Yes | Harald Kliems kliems@wisc.edu | Jill Denson, jdenson@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueelPmWnQuU2VwOINnwkPYB0k85vDf7yXY_erJtsdzNjp8gxunz1s6lyhdb7Z6kOK8 | ||||||||||
| Noonan@ortho.wisc.edu | Ken | Noonan | MD MHCDS | Analysis of Long Arm Casting for Forearm Fractures | 608 | Orthopedics and Rehabilitation | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Analysis of Long Arm Casting for Forearm Fractures: This will be a retrospective analysis of long-arm casts for forearm fractures in children. We will compare outcomes from a long arm cast with the elbow flexed to 90° versus a long arm cast for arms fully extended. Our primary outcome variable will be fracture alignment upon healing. ____________________________________________________________________________ Role - Will develop a protocol for data to be collected, gain IRB approval for this study and do medical chart and radiographic analysis.; IRB Status - WILL NEED TO BE APPLIED FOR; Skills - Ability to review medical records and to learn how to read and measure radiographs | Pediatric Orthopaedics | Analysis of Long Arm Casting for Forearm Fractures | This will be a retrospective analysis of long-arm casts for forearm fractures in children. We will compare outcomes from a long arm cast with the elbow flexed to 90° versus a long arm cast for arms fully extended. Our primary outcome variable will be fracture alignment upon healing. | 1 | Will develop a protocol for data to be collected, gain IRB approval for this study and do medical chart and radiographic analysis. | Moderate | Ability to review medical records and to learn how to read and measure radiographs | WILL NEED TO BE APPLIED FOR | No | Yes | Yes | Not currently available to mentor other students | No | Yes | Maria Flory ; Laura McCarty BRITTANY ANN GRASSO | Ken Noonan, Noonan@ortho.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufLB7nA203j-dcbwnL4BKWiOCseknlrbYoZkMQEWQe5HrWlA09z9wL4lf_vomMynDM | ||||||||
| shih@ortho.wisc.edu | Celestine | Shih | M.D. | Assistant Professor | Orthopedics and Rehabilitation | Shorter term projects, Research Electives for credit, Clinical research projects in pediatric orthopaedics | Risk factors for physeal arrest of distal tibia Salter Harris type II fractures: Premature physeal arrest (early closure of the growth plate) after a fracture of the distal tibia (shin bone just above the ankle) can cause a leg to grow shorter or crooked, affecting the way a patient walks and how their legs look. Our project hopes to answer these questions about distal tibia Salter Harris type 2 fractures: (1) How much displacement of the growth plate increases the risk of physeal arrest? Literature so far has established a cutoff of 2.5 mm or more. (2) Does surgery make a difference in the rate of growth arrest in those fractures with >2.5 mm of displacement? (3) If physeal displacement is not the only risk factor for physeal arrest, what are other factors? It will involve retrospective chart review of distal tibia Salter Harris type II fractures that have been managed at UW-Madison since 2000 (or the earliest year when UW started using HealthLink). After extracting variables of interest, we will conduct statistical analysis to see if certain variables correlate with premature physeal arrest, as described in the questions above. The Shapiro scholar will have the opportunity to draft an initial abstract/poster and manuscript, then revise, submit, and present the abstract at various forums. ____________________________________________________________________________ Role - Data collection and analysis, manuscript writing and submission; IRB Status - In process of submission; Skills - None - only need to be organized and interested! Skills with statistics and medical chart review are helpful but not required. We will provide training in medical chart review and x-ray measurements. | Pediatric Orthopaedic Surgery | Risk factors for physeal arrest of distal tibia Salter Harris type II fractures | Premature physeal arrest (early closure of the growth plate) after a fracture of the distal tibia (shin bone just above the ankle) can cause a leg to grow shorter or crooked, affecting the way a patient walks and how their legs look. Our project hopes to answer these questions about distal tibia Salter Harris type 2 fractures: (1) How much displacement of the growth plate increases the risk of physeal arrest? Literature so far has established a cutoff of 2.5 mm or more. (2) Does surgery make a difference in the rate of growth arrest in those fractures with >2.5 mm of displacement? (3) If physeal displacement is not the only risk factor for physeal arrest, what are other factors? It will involve retrospective chart review of distal tibia Salter Harris type II fractures that have been managed at UW-Madison since 2000 (or the earliest year when UW started using HealthLink). After extracting variables of interest, we will conduct statistical analysis to see if certain variables correlate with premature physeal arrest, as described in the questions above. The Shapiro scholar will have the opportunity to draft an initial abstract/poster and manuscript, then revise, submit, and present the abstract at various forums. | 0 | Data collection and analysis, manuscript writing and submission | None - only need to be organized and interested! Skills with statistics and medical chart review are helpful but not required. We will provide training in medical chart review and x-ray measurements. | In process of submission | No | Yes | Yes | Not currently available to mentor other students | No | No | Heidi Abledinger (ableidinger@ortho.wisc.edu), Laura McCarty (laura.mccarty@wisc.edu) | Celestine Shih, shih@ortho.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucCss8z5CQuhSV_RZaUwgXN476a4SIyytsFPXnfD462nkTbDFvEiamap50kMuvFCd4 | ||||||||||
| jdkratz@medicine.wisc.edu | Jeremy | Kratz | MD | Assistant Professor | 608 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Genomic Signatures in Pancreatic Cancer Prediction: Next-generation sequencing has expanded our understanding of point alterations, gene amplifications/loss and fusion events. While this has integrated into clinical practice, the analysis of genomic elements must including emerging signatures. The University of Wisconsin's Precision Medicine Molecular tumor board has included >12,000 annotated genomics profiles. Here, we will analyze alterations in homologous recombination deficiency defined by traditional methods (mutation frequency) versus genomic signatures as an emerging biomarker in pancreatic cancer. We will analyze the efficacy of chemotherapy regimen using Kaplan Meier analysis controlled for covariables. ____________________________________________________________________________ Role - Research Assistant; IRB Status - Approved; Skills - Interest in oncology, basic microsoft excel, chart review | Hematology, Oncology and Palliative Care | Genomic Signatures in Pancreatic Cancer Prediction | Next-generation sequencing has expanded our understanding of point alterations, gene amplifications/loss and fusion events. While this has integrated into clinical practice, the analysis of genomic elements must including emerging signatures. The University of Wisconsin's Precision Medicine Molecular tumor board has included >12,000 annotated genomics profiles. Here, we will analyze alterations in homologous recombination deficiency defined by traditional methods (mutation frequency) versus genomic signatures as an emerging biomarker in pancreatic cancer. We will analyze the efficacy of chemotherapy regimen using Kaplan Meier analysis controlled for covariables. | 0 | Research Assistant | 2 | Interest in oncology, basic microsoft excel, chart review | Approved | Yes | No (plan to use Dean's Office Funds) | Yes | PhD students, UW undergraduates interested in research | No | No | Austin Stram (astram@wisc.edu) | Jeremy Kratz, jdkratz@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudOfiIV6_8envNKWoTusDttLXoCHzlcsWCHADHLqN9ykTOMwf57gP7K9yVIQRs4Dwo | ||||||||
| 01/02/2025 | abel@urology.wisc.edu | E Jason | Abel | MD | Professor, Chief of Urologic Oncology | 608 | Urology | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Kidney cancer projects: I am a urologic oncologist who does research primarily in kidney cancer. I have several clinical/translational research projects that would be ideal for a Shapiro Summer Student. I have worked with of 28 Shapiro students in the past summers and have publications with almost all of them. Let me know if you would like to talk about prospective projects. ____________________________________________________________________________ Role - Mentored independence; IRB Status - approved; Skills - effort and basic medical knowledge | Kidney cancer projects | I am a urologic oncologist who does research primarily in kidney cancer. I have several clinical/translational research projects that would be ideal for a Shapiro Summer Student. I have worked with of 28 Shapiro students in the past summers and have publications with almost all of them. Let me know if you would like to talk about prospective projects. | 1 | Mentored independence | We will work closely during the summer for the best results. | effort and basic medical knowledge | approved | Yes | Yes | Yes | Genetic Counseling students, MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | Unsure / Depends | Dee Mussehl mussehl@urology.wisc.edu | E Jason Abel, abel@urology.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuftpVzSUNyzco9umWoJwbocqPRTEDuODpiDIzpbpuNjp5nGEOkPyKp_MYIiWiwedXc | ||||||||
| 01/03/2025 | selkie@wisc.edu | Ellen | Selkie | MD, MPH | Assistant Professor | Pediatrics | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Health Information Presented by Transgender and Gender Diverse Creators on YouTube: The Learning More From Adolescents Online (LMFAO) Research Team (lmfaoteam.org) seeks to identify ways to promote well-being for adolescents and young adults when using technology and digital media, with a special focus on gender diverse youth. The current project examines a dataset of YouTube videos produced by popular transgender and gender diverse creators. The student working on this project will systematically evaluate videos containing health information on gender affirming care for accuracy and evidence, with the goal being to quantify the health education potential of social media content for gender diverse individuals. Students working with the LMFAO Team through the Shapiro program will gain: 1) experience in literature reviews, interview skills and qualitative data collection and analysis; 2) opportunities for abstract submission and publication; 3) work with a dynamic interdisciplinary team with psychology and public health backgrounds; research and career mentoring from Dr. Selkie, an Adolescent Medicine physician ____________________________________________________________________________ Role - The student will use the medical literature to evaluate health-related videos for accuracy. Tasks will include literature review, coding of study videos, and preparation of descriptive data for presentation.; IRB Status - N/A; Skills - Basic literature search skills, Microsoft Excel | General Pediatrics and Adolescent Medicine | Health Information Presented by Transgender and Gender Diverse Creators on YouTube | The Learning More From Adolescents Online (LMFAO) Research Team (lmfaoteam.org) seeks to identify ways to promote well-being for adolescents and young adults when using technology and digital media, with a special focus on gender diverse youth. The current project examines a dataset of YouTube videos produced by popular transgender and gender diverse creators. The student working on this project will systematically evaluate videos containing health information on gender affirming care for accuracy and evidence, with the goal being to quantify the health education potential of social media content for gender diverse individuals. Students working with the LMFAO Team through the Shapiro program will gain: 1) experience in literature reviews, interview skills and qualitative data collection and analysis; 2) opportunities for abstract submission and publication; 3) work with a dynamic interdisciplinary team with psychology and public health backgrounds; research and career mentoring from Dr. Selkie, an Adolescent Medicine physician | 0 | The student will use the medical literature to evaluate health-related videos for accuracy. Tasks will include literature review, coding of study videos, and preparation of descriptive data for presentation. | Basic literature search skills, Microsoft Excel | N/A | Yes | Yes | Yes | Not currently available to mentor other students | No | Unsure / Depends | Christine Richards crichards9@wisc.edu, Lydia Bliss lsbliss@wisc.edu | Ellen Selkie, selkie@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucBtBtqfhQQsKoX0xUqJmZKoQ-cwR3567BSIcnvVz8Ckc3XrU0R6OXBpE1Eq5SOtVo | |||||||||
| 01/06/2025 | sccraig2@wisc.edu | Pallavi | Tiwari | PhD | Associate Professor | Radiology | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Multimodal Prediction of Ischemic Stroke post Transient Ischemic Attack: The project aims at predicting of onset of stroke in at risk population by utilizing multimodal data including text and radiology images. ____________________________________________________________________________ Role - Medical data extraction, lesion annotation, literature review, data analysis for submissions to conferences and papers; IRB Status - N/A; Skills - Basic Research Knowledge | Multimodal Prediction of Ischemic Stroke post Transient Ischemic Attack | The project aims at predicting of onset of stroke in at risk population by utilizing multimodal data including text and radiology images. | 1 | Medical data extraction, lesion annotation, literature review, data analysis for submissions to conferences and papers | Basic Research Knowledge | N/A | No | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | Unsure / Depends | Unsure / Depends | Stephen Craig, sccraig2@wisc.edu | Pallavi Tiwari, sccraig2@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufWy4bO68JasqEjGbMLsmwm8B2iAPDSlL5CkhCmeDKBkpMTEeUoDFtNSLBQ_If_ytM | ||||||||||
| beckan@surgery.wisc.edu | Anna | Beck | MD | Assistant Professor | Surgery | Shorter term projects, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Lobular Carcinoma in Situ Incidence Rates and Patient Outcomes in a Hybrid Multidisciplinary Academic and Community-Based Practice: With a multidisciplinary team of a breast radiologist, breast pathologist and breast surgeon, we are utilizing a cohort of patients identified on screening mammograms to have benign lesions that are considered to be "high risk" for a future breast cancer. Incidence has been shown to change over time based on screening guidelines, however incidence on different types of imaging has not been described. Additionally, our multidisciplinary team established a protocol to monitor select lesions, rather than surgically excise them all and the effect of these guidelines has yet to been described. Our research approach will be to complete a retrospective chart review that is currently IRB approved of patients with two types of high risk lesions (LCIS and ALH) to identify the incidence of LCIS and ALH overtime and assess the impact of a multidisciplinary guideline implemented in 2006 on patient outcomes. In addition to completion of the retrospective chart review of the electronic medical record, this project will include learning how to perform and apply basic statistical analyses, as well as abstract and manuscript writing. ____________________________________________________________________________ Role - As the student on this project, you will primarily be responsible for organization of data in RedCap and completion of the retrospective chart review with the goal of writing 1 to 2 abstracts to be submitted to a national breast cancer related meeting. The ultimate goal will also be to complete a manuscript associated with each abstract. Opportunities for performing basic statistical analysis of the data and learning how to present those data in a presentation and manuscript are available for those interested. ; IRB Status - Obtained; Skills - Comfort with using an excel file | Surgical Oncology | Lobular Carcinoma in Situ Incidence Rates and Patient Outcomes in a Hybrid Multidisciplinary Academic and Community-Based Practice | With a multidisciplinary team of a breast radiologist, breast pathologist and breast surgeon, we are utilizing a cohort of patients identified on screening mammograms to have benign lesions that are considered to be "high risk" for a future breast cancer. Incidence has been shown to change over time based on screening guidelines, however incidence on different types of imaging has not been described. Additionally, our multidisciplinary team established a protocol to monitor select lesions, rather than surgically excise them all and the effect of these guidelines has yet to been described. Our research approach will be to complete a retrospective chart review that is currently IRB approved of patients with two types of high risk lesions (LCIS and ALH) to identify the incidence of LCIS and ALH overtime and assess the impact of a multidisciplinary guideline implemented in 2006 on patient outcomes. In addition to completion of the retrospective chart review of the electronic medical record, this project will include learning how to perform and apply basic statistical analyses, as well as abstract and manuscript writing. | 0 | As the student on this project, you will primarily be responsible for organization of data in RedCap and completion of the retrospective chart review with the goal of writing 1 to 2 abstracts to be submitted to a national breast cancer related meeting. The ultimate goal will also be to complete a manuscript associated with each abstract. Opportunities for performing basic statistical analysis of the data and learning how to present those data in a presentation and manuscript are available for those interested. | All levels of research experience are welcome | Comfort with using an excel file | Obtained | No | Potential funding available through the Peter and Myra Berk Cristall Breast Cancer Research Fund | Yes | Genetic Counseling students, MPH students, PhD students, UW undergraduates interested in research | No | Yes | Amber Andrews (amber.andrews@wisc.edu), Heather Neuman (neuman@surgery.wisc.edu), Sharon Weber (webers@surgery.wsic.edu) | Anna Beck, beckan@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnud0y1iI-h4xLHLQKU4BVgCA2q6-yGrwAE8GkYKvkCMUMJIMl0w6Na-wHGayWxg7xx4 | |||||||||
| beckan@surgery.wisc.edu | Anna | Beck | MD | Assistant Professor | Surgery | Shorter term projects, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Identification of Multiomic Prognostic Markers of Recurrence and Survival in Node Positive Invasive Lobular Carcinoma: This is a translational project that will look at correlations between somatic mutations and levels of gene expression and recurrence. Invasive lobular carcinoma can present with a high burden of lymph node positive disease, however a portion of these patients will never have a cancer recurrence. Current prognostic markers are not well established. Using the MSK IMPACT, TCGA and METABRIC databases, we will investigate multiomic prognostic markers for recurrence in patients with node positive invasive lobular carcinoma. ____________________________________________________________________________ Role - Data analysis, figure design, abstract writing, manuscript writing; IRB Status - N/A; Skills - Interest in translational research. | Surgical Oncology | Identification of Multiomic Prognostic Markers of Recurrence and Survival in Node Positive Invasive Lobular Carcinoma | This is a translational project that will look at correlations between somatic mutations and levels of gene expression and recurrence. Invasive lobular carcinoma can present with a high burden of lymph node positive disease, however a portion of these patients will never have a cancer recurrence. Current prognostic markers are not well established. Using the MSK IMPACT, TCGA and METABRIC databases, we will investigate multiomic prognostic markers for recurrence in patients with node positive invasive lobular carcinoma. | 0 | Data analysis, figure design, abstract writing, manuscript writing | Interest in translational research. | N/A | No | Potential funding through the Peter and Myra Berk Cristall Cancer Research Fund | Yes | Genetic Counseling students, MPH students, PhD students, UW undergraduates interested in research | No | No | Amber Andrews, Heather Neuman, Sharon Weber | Anna Beck, beckan@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucfgRXt-1SijFzEQ5auW6l5H3XM8Nli4DLnmKlyfBCwSwWPdfD5-ZetSR1djjdaDWs | ||||||||||
| 01/07/2025 | kshadman@pediatrics.wisc.edu | Kristin | Shadman | MD | Professor of Pediatrics | Pediatrics | Not currently interested or available for Non-Shapiro research mentoring of medical students | Decreasing Daily Dings- a QI study to decrease unnecessary Securechats: Interested in learning about quality improvement and qualitative methods? Join us to help decrease the incessant interruptions created by secure messaging in the EHR. We are looking for two students to help us perform a background literature review, obtain data through direct observation of residents, nurses, and other care team members’ work, analyze qualitative and quantitative QI data from secure messages, and help inform interventions aimed at decreasing the number of secure messages sent each day. In addition to close mentorship and guided asynchronous lessons in qualitative and QI methods, students will have the opportunity to interact with many members of the health care team and observe clinical care in general care and procedural sedation settings. ____________________________________________________________________________ Role - Students will perform a background literature review, obtain qualitative, data through direct observation of residents, nurses, and other care team members’ work, analyze qualitative as well as quantitative data from a database of messages. Once the project is underway, students will check in with the team on a weekly basis, as well as with the coordinator weekly. They will meet more frequently initially, with virtual options. Team is available for short check-ins as needed. Vacation or travel during this summer research internship is possible, but must be discussed prior. ; IRB Status - Depending on which component of the project, will be either QI self-service or minimal risk ; Skills - Experience with excel is preferred, but not required, however students will be most successful if they can do some self-directed learning using recorded tutorials for excel, include add-in QI software to create charts. | Hospital Medicine | Dan Sklansky | djsklansky@pediatrics.wisc.edu | Pediatrics | Hospital Medicine | Decreasing Daily Dings- a QI study to decrease unnecessary Securechats | Interested in learning about quality improvement and qualitative methods? Join us to help decrease the incessant interruptions created by secure messaging in the EHR. We are looking for two students to help us perform a background literature review, obtain data through direct observation of residents, nurses, and other care team members’ work, analyze qualitative and quantitative QI data from secure messages, and help inform interventions aimed at decreasing the number of secure messages sent each day. In addition to close mentorship and guided asynchronous lessons in qualitative and QI methods, students will have the opportunity to interact with many members of the health care team and observe clinical care in general care and procedural sedation settings. | 2 | Students will perform a background literature review, obtain qualitative, data through direct observation of residents, nurses, and other care team members’ work, analyze qualitative as well as quantitative data from a database of messages. Once the project is underway, students will check in with the team on a weekly basis, as well as with the coordinator weekly. They will meet more frequently initially, with virtual options. Team is available for short check-ins as needed. Vacation or travel during this summer research internship is possible, but must be discussed prior. | Semi-autonomous | Experience with excel is preferred, but not required, however students will be most successful if they can do some self-directed learning using recorded tutorials for excel, include add-in QI software to create charts. | Depending on which component of the project, will be either QI self-service or minimal risk | No | Yes | Yes | UW undergraduates interested in research | No | Yes | N/A | Kristin Shadman, kshadman@pediatrics.wisc.edu -- Co-Mentor: Dan Sklansky djsklansky@pediatrics.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufBKQ8B-M3TjCGOIoKwsvfmy1trSa4nVadW6csfi-cNNURYj3GrM1YVvYjF9xn-fMs | ||||
| 01/07/2025 | nkumar39@wisc.edu | Nilay | Kumar | MD | Assistant Professor | 205 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Racial-ethnic differences in outcomes after hospitalization for hypertensive emergency: This project aims to study racial-ethnic differences in hospitalization outcomes for patients admitted with hypertensive emergency. We will use the National Inpatient Sample database to identify hospitalizations with a principal diagnosis of hypertensive emergency. The outcomes of interest will include in-hospital mortality, hospital length of stay, cost of hospitalization. We will use multivariable regression models to ascertain differences in outcomes after adjusting for relevant confounders. We will also construct models to attempt to understand potential mechanisms for differences in outcomes. ____________________________________________________________________________ Role - Assist mentor in conducting the aforementioned analyses using statistical software, summarize the results in the form of tables/figures, work on preparing and submitting a poster for local/regional/national presentation. ; IRB Status - n/a; Skills - none | Hospital Medicine | Racial-ethnic differences in outcomes after hospitalization for hypertensive emergency | This project aims to study racial-ethnic differences in hospitalization outcomes for patients admitted with hypertensive emergency. We will use the National Inpatient Sample database to identify hospitalizations with a principal diagnosis of hypertensive emergency. The outcomes of interest will include in-hospital mortality, hospital length of stay, cost of hospitalization. We will use multivariable regression models to ascertain differences in outcomes after adjusting for relevant confounders. We will also construct models to attempt to understand potential mechanisms for differences in outcomes. | 0 | Assist mentor in conducting the aforementioned analyses using statistical software, summarize the results in the form of tables/figures, work on preparing and submitting a poster for local/regional/national presentation. | limited | none | n/a | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Yes | n/a | Nilay Kumar, nkumar39@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnue3BubNrdtt2ZB9UUCq1zmQJFYkxMqTlTHi4qsNJ-2NXqw-01PGcWCz5Jda-ID_c2A | |||||||
| 01/08/2025 | mmessina@medicine.wisc.edu | Christie | Bartels | MD | Division Chief | 0 | Medicine | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Lupus Eye Exam Study: UW researchers are federally funded to innovatively study offering eye exams directly in the rheumatology clinic for patients with lupus taking hydroxychloroquine (HCQ) using new technology. HCQ saves lives and reduces disease damage and patients only need annual eye exams to monitor. Delays in ophthalmology testing threaten adherence disparities although risk of eye toxicity from HCQ is low. This study requires baseline data to be abstracted from the EHR on patients with lupus meeting inclusion criteria. Baseline rates will be manually abstracted by study team members into a REDCap form for 100 patients using abstraction processes previously used by our group. An essential item will be the scanned outside eye exam results to referrals as well as capturing internal optometry and ophthalmology visit notes to track actual screening rates pre and post. Learners interested in lupus,ophthalmology, internal medicine, or health disparities are encouraged to apply. ____________________________________________________________________________ Role - Reviewing patient records in EHR to find demographic data and any imaging related to eye exams; IRB Status - Review underway; decision expected by Feb 2025; Skills - Must have familiarity with searching records in Epic | Rheumatology | Lupus Eye Exam Study | UW researchers are federally funded to innovatively study offering eye exams directly in the rheumatology clinic for patients with lupus taking hydroxychloroquine (HCQ) using new technology. HCQ saves lives and reduces disease damage and patients only need annual eye exams to monitor. Delays in ophthalmology testing threaten adherence disparities although risk of eye toxicity from HCQ is low. This study requires baseline data to be abstracted from the EHR on patients with lupus meeting inclusion criteria. Baseline rates will be manually abstracted by study team members into a REDCap form for 100 patients using abstraction processes previously used by our group. An essential item will be the scanned outside eye exam results to referrals as well as capturing internal optometry and ophthalmology visit notes to track actual screening rates pre and post. Learners interested in lupus,ophthalmology, internal medicine, or health disparities are encouraged to apply. | 0 | Reviewing patient records in EHR to find demographic data and any imaging related to eye exams | Moderately Independent | Must have familiarity with searching records in Epic | Review underway; decision expected by Feb 2025 | Yes | Yes | Yes | MPH students, PhD students | No | Yes | Monica Messina, mmessina@medicine.wisc.edu | Christie Bartels, mmessina@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufSnodKPsp4Vxdy964ATFBggALPmFEH0ig3QtfR7J0pv44cPxt49w5FVmfzrB8aB9g | |||||||
| 01/09/2025 | dunahoe@ortho.wisc.edu | Jacquelyn | Dunahoe | MD | Dr. | 6.082.636.938 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | Analyzing Outcomes of Geriatric Hip Fractures at University Hospital: Hip fractures are one of the most common injuries in geriatric patients. Additionally, they are associated with significant morbidity and mortality. The goal of this study is to evaluate the outcomes of geriatric hip fracture care at UH. ____________________________________________________________________________ Role - The student will perform a literature review on the subject and in the process, draft an introduction for the research manuscript. Throughout the summer, the student will perform retrospective chart reviews of patients eligible for inclusion in the study. This will involve reviewing clinical progress notes, operative reports, and radiology reports, along with basic interpretation of radiographs and CT scans. The student will also work closely with our departmental statistician to plan and later analyze any statistical analyses relevant to the study. The student will also work toward drafting a full manuscript later in the summer, along with preparing a poster for the Shapiro Fall Research Symposium. Finally, there will be opportunities for the student to shadow Orthopedic surgeons in clinic and in the operating room throughout the summer.; IRB Status - In Progress; Skills - Proficiency in Excel, medical chart review/navigating EHR, ability to learn and apply basic X-ray interpretation skills, attention to detail and data organization and analysis, effective oral and communication skills, independent problem solving skills. | Orthopedic Trauma | N/A | Dr. Paul Whiting | whiting@ortho.wisc.edu | Orthopedics and Rehabilitation | Orthopedic Trauma | Analyzing Outcomes of Geriatric Hip Fractures at University Hospital | Hip fractures are one of the most common injuries in geriatric patients. Additionally, they are associated with significant morbidity and mortality. The goal of this study is to evaluate the outcomes of geriatric hip fracture care at UH. | 0 | The student will perform a literature review on the subject and in the process, draft an introduction for the research manuscript. Throughout the summer, the student will perform retrospective chart reviews of patients eligible for inclusion in the study. This will involve reviewing clinical progress notes, operative reports, and radiology reports, along with basic interpretation of radiographs and CT scans. The student will also work closely with our departmental statistician to plan and later analyze any statistical analyses relevant to the study. The student will also work toward drafting a full manuscript later in the summer, along with preparing a poster for the Shapiro Fall Research Symposium. Finally, there will be opportunities for the student to shadow Orthopedic surgeons in clinic and in the operating room throughout the summer. | As described above (and below), the student will be expected to work fairly independently on chart reviews after receiving appropriate training from the faculty mentor, orthopaedic resident (co-mentor), and our clinical research coordinator. Ongoing oversight and mentoring will be provided throughout the summer. | Proficiency in Excel, medical chart review/navigating EHR, ability to learn and apply basic X-ray interpretation skills, attention to detail and data organization and analysis, effective oral and communication skills, independent problem solving skills. | In Progress | No | Yes | Yes | Not currently available to mentor other students | No | No | Kris Sladky, Ortho Trauma Research Coordinator – sladky@ortho.wisc.edu; otrc@ortho.wisc.edu Dr. Paul Whiting – whiting@ortho.wisc.edu | Jacquelyn Dunahoe, dunahoe@ortho.wisc.edu -- Co-Mentor: Dr. Paul Whiting whiting@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucoPLCDAzqxBWUFudbuuj0dphQuh9Fx-Cj5C7KdB0vPWYUKazbIB2nC3CFwaXz6e_k | ||
| 01/09/2025 | dunahoe@ortho.wisc.edu | Jacquelyn | Dunahoe | MD | Dr. | 6.082.636.938 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | Evaluating the Co-Occurrence of Osteoperosis in Patients with Acute Ankle Fracture: Ankle features are one of the most common orthopedic injuries. Many of patients with ankle are treated operatively and found to have poor bone quality. The aim of this study is to evaluate the presence of osteoporosis based upon CT and surgeon intra-operative evaluation in patients with acute ankle fractures. ____________________________________________________________________________ Role - The student will perform a literature review on the subject and in the process, draft an introduction for the research manuscript. Throughout the summer, the student will perform retrospective chart reviews of patients eligible for inclusion in the study. This will involve reviewing clinical progress notes, operative reports, and radiology reports, along with basic interpretation of radiographs and CT scans. The student will also work closely with our departmental statistician to plan and later analyze any statistical analyses relevant to the study. The student will also work toward drafting a full manuscript later in the summer, along with preparing a poster for the Shapiro Fall Research Symposium. Finally, there will be opportunities for the student to shadow Orthopedic surgeons in clinic and in the operating room throughout the summer.; IRB Status - In Progress; Skills - Proficiency in Excel, medical chart review/navigating EHR, ability to learn and apply basic X-ray interpretation skills, attention to detail and data organization and analysis, effective oral and communication skills, independent problem solving skills. | Orthopedic Trauma | Paul Whiting | whiting@ortho.wisc.edu | Orthopedics and Rehabilitation | Orthopedic Trauma | Evaluating the Co-Occurrence of Osteoperosis in Patients with Acute Ankle Fracture | Ankle features are one of the most common orthopedic injuries. Many of patients with ankle are treated operatively and found to have poor bone quality. The aim of this study is to evaluate the presence of osteoporosis based upon CT and surgeon intra-operative evaluation in patients with acute ankle fractures. | 0 | The student will perform a literature review on the subject and in the process, draft an introduction for the research manuscript. Throughout the summer, the student will perform retrospective chart reviews of patients eligible for inclusion in the study. This will involve reviewing clinical progress notes, operative reports, and radiology reports, along with basic interpretation of radiographs and CT scans. The student will also work closely with our departmental statistician to plan and later analyze any statistical analyses relevant to the study. The student will also work toward drafting a full manuscript later in the summer, along with preparing a poster for the Shapiro Fall Research Symposium. Finally, there will be opportunities for the student to shadow Orthopedic surgeons in clinic and in the operating room throughout the summer. | As described above (and below), the student will be expected to work fairly independently on chart reviews after receiving appropriate training from the faculty mentor, orthopaedic resident (co-mentor), and our clinical research coordinator. Ongoing oversight and mentoring will be provided throughout the summer. | Proficiency in Excel, medical chart review/navigating EHR, ability to learn and apply basic X-ray interpretation skills, attention to detail and data organization and analysis, effective oral and communication skills, independent problem solving skills. | In Progress | No | Yes | Yes | Not currently available to mentor other students | No | No | Kris Sladky, Ortho Trauma Research Coordinator – sladky@ortho.wisc.edu; otrc@ortho.wisc.edu Dr. Paul Whiting – whiting@ortho.wisc.edu | Jacquelyn Dunahoe, dunahoe@ortho.wisc.edu -- Co-Mentor: Paul Whiting whiting@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnue5sNem86Lcrya1ge3UdkEirR9FKgZsvdoDFh1Nwz_h40phQQLCJRCzeaz6xflF0Ac | |||
| 01/10/2025 | ltaylor@medicine.wisc.edu | Lindsay | Taylor | MD, MS | Assistant Professor | 414 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Developing equity-informed antibiotic stewardship measures: Disparities in the prevalence of multidrug-resistant infections, infectious disease outcomes, and inappropriate antimicrobial use have been reported across minority populations. As a first step to combat these differences, we must identify them and stratify antibiotic use and outcome measures by race, ethnicity, and language (REaL) data available in the medical record. The goal of this study is to obtain preliminary data to support development of equity-informed measures of antibiotic use. This will be accomplished through a retrospective chart review of hospitalized patients with one of 4 common infections (SSTI, CAP, and UTI) with the main outcome of guideline concordant therapy, exploring differences in outcomes based on REaL variables. Interested student researcher will help with chart abstraction and data analysis. ____________________________________________________________________________ Role - the role of the student will involve literature review, data collection and entry, abstract/manuscript writing and submission; IRB Status - application pending; Skills - Data collection, chart abstraction from Epic, willingness to learn REDCap | Infectious Disease | Jessica Tischendorft, MD, MS | jtischen@medicine.wisc.edu | Medicine | Infectious Disease | Developing equity-informed antibiotic stewardship measures | Disparities in the prevalence of multidrug-resistant infections, infectious disease outcomes, and inappropriate antimicrobial use have been reported across minority populations. As a first step to combat these differences, we must identify them and stratify antibiotic use and outcome measures by race, ethnicity, and language (REaL) data available in the medical record. The goal of this study is to obtain preliminary data to support development of equity-informed measures of antibiotic use. This will be accomplished through a retrospective chart review of hospitalized patients with one of 4 common infections (SSTI, CAP, and UTI) with the main outcome of guideline concordant therapy, exploring differences in outcomes based on REaL variables. Interested student researcher will help with chart abstraction and data analysis. | 0 | the role of the student will involve literature review, data collection and entry, abstract/manuscript writing and submission | moderate | Data collection, chart abstraction from Epic, willingness to learn REDCap | application pending | No | No (plan to use Dean's Office Funds) | Yes | MPH students | No | No | N/A | Lindsay Taylor, ltaylor@medicine.wisc.edu -- Co-Mentor: Jessica Tischendorft, MD, MS jtischen@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudiXjKSuSIbE52THuVxuUKLQ7K4Pp0s7gt_OHWFlaRu5T21dQQA7v84g4g1MsCAtYg | |||
| 01/10/2025 | khoppe2@wisc.edu | Kara | Hoppe | DO, PhD | Associate Professor | 608 | Obstetrics & Gynecology | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Clinical and Immune Predictors of Postpartum Hypertension: We are merging labs and bringing bench to clinical science together to answer questions around pregnancy and postpartum hypertension. We have preliminary data on longitudinal patient serum with clinical outpatient hypertension data to start assessing immunologic and cytokine influences on BP behavior before and after birth. We will expand our patient recruitment and sample size in this project and hope to identify potential biomarkers and/or therapeutic strategies to lower the risk of BP spikes and associated morbidities after delivery - and potentially identify people at risk long-term of adverse CV outcomes in years after a pregnancy complicated by hypertension. https://www.obgyn.wisc.edu/researchlab/2297 https://www.obgyn.wisc.edu/stac/about ____________________________________________________________________________ Role - REDCap data entry, involvement in subject recruitment, learning to perform bench assays and cytokine analyses, manuscript and potential grant writing; IRB Status - approved; Skills - Previous bench and/or clinical research experiece. | OBGYN | Aleks Stanic-Kostic | stanickostic@wisc.edu | Obstetrics & Gynecology | Clinical and Immune Predictors of Postpartum Hypertension | We are merging labs and bringing bench to clinical science together to answer questions around pregnancy and postpartum hypertension. We have preliminary data on longitudinal patient serum with clinical outpatient hypertension data to start assessing immunologic and cytokine influences on BP behavior before and after birth. We will expand our patient recruitment and sample size in this project and hope to identify potential biomarkers and/or therapeutic strategies to lower the risk of BP spikes and associated morbidities after delivery - and potentially identify people at risk long-term of adverse CV outcomes in years after a pregnancy complicated by hypertension. https://www.obgyn.wisc.edu/researchlab/2297 https://www.obgyn.wisc.edu/stac/about | 0 | REDCap data entry, involvement in subject recruitment, learning to perform bench assays and cytokine analyses, manuscript and potential grant writing | significant with oversite from mentors | Previous bench and/or clinical research experiece. | approved | No | Yes | Yes | Not currently available to mentor other students | No | No | NA | Kara Hoppe, khoppe2@wisc.edu -- Co-Mentor: Aleks Stanic-Kostic stanickostic@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudGYZOmM3cNY4cbi9qqjF7_OX_JV6gJQoUluh4wQGyz9UN8llSSIoYuSTG1zQHptFs | ||||
| 01/10/2025 | RCHANNA@WISC.EDU | Roomasa | Channa | MD | Assistant Professor | Ophthalmology and Visual Sciences | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Eye screening services for diabetes at clinics in Wisconsin : Evaluate existing diabetic eye care services provided by Wisconsin FQHCs, including screenings, treatment options, and referral process. The project will involve contacting clinics and ascertaining data from clinic staff. ____________________________________________________________________________ Role - The project will involve contacting clinics and ascertaining data from clinic staff, entering data in REDCap, writing and presenting the results. ; IRB Status - pending ; Skills - Good inter-personal and communication skills | Eye screening services for diabetes at clinics in Wisconsin | Evaluate existing diabetic eye care services provided by Wisconsin FQHCs, including screenings, treatment options, and referral process. The project will involve contacting clinics and ascertaining data from clinic staff. | 1 | The project will involve contacting clinics and ascertaining data from clinic staff, entering data in REDCap, writing and presenting the results. | Good inter-personal and communication skills | pending | Yes | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | Yes | Yes | bahranian@wisc.edu | Roomasa Channa, RCHANNA@WISC.EDU -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuftOjjvcq1OwBMNlrwwvFmVVGMcZaEsTxabjHT9MqsS-Tl3Ub1TndvITKP1NmOFuag | ||||||||||
| 01/12/2025 | erwald@wisc.edu | Ellen | Wald | MD | Professor of Pediatrics | 412 | Pediatrics | Not sure at this time | Suprapubic aspiration as preferred method to obtain sample in suspected urinary tract infection: Obtaining a sample of urine that is uncontamined from a neonate in whom a urinary tract infection is suspected is challenging. Although suprapubic aspiration was commonly performed in the past, more recently, urine samples are obtained via urethral catheterization. Unfortunately, samples obtained by catheterization are prone to contamination and therefore complicate interpretation of the culture result. The principal reasons for abandoning suprapubic aspiration in the past related to "dry" taps and concern about discomfort. Given the availability of ultrasound evaluations to assure that the bladder is full and topical anesthetics to reduce cutaneous discomfort, suprapubic aspiration should be re-evaluated as the preferred method to obtain urine for culture in the neonate. ____________________________________________________________________________ Role - Literature review and data analysis; IRB Status - Not applicable; Skills - Inquiring mind | Infectious Diseases | Gregory DeMuri Professor of Pediatrics | demuri@pediatrics.wisc.edu | Pediatrics | Infectious Diseases | Suprapubic aspiration as preferred method to obtain sample in suspected urinary tract infection | Obtaining a sample of urine that is uncontamined from a neonate in whom a urinary tract infection is suspected is challenging. Although suprapubic aspiration was commonly performed in the past, more recently, urine samples are obtained via urethral catheterization. Unfortunately, samples obtained by catheterization are prone to contamination and therefore complicate interpretation of the culture result. The principal reasons for abandoning suprapubic aspiration in the past related to "dry" taps and concern about discomfort. Given the availability of ultrasound evaluations to assure that the bladder is full and topical anesthetics to reduce cutaneous discomfort, suprapubic aspiration should be re-evaluated as the preferred method to obtain urine for culture in the neonate. | 1 | Literature review and data analysis | Minimal | Inquiring mind | Not applicable | Yes | Yes | Yes | Not currently available to mentor other students | Yes | No | Julene Gaspard | Ellen Wald, erwald@wisc.edu -- Co-Mentor: Gregory DeMuri Professor of Pediatrics demuri@pediatrics.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueCJ78HkA1z2y_nx6Ep4RQ5tkBVvTOheJE8JmpJOI3f8hwK_XR_YNq4CoANnvxZjXI | |||
| 01/12/2025 | jfloberg@humonc.wisc.edu | John | Floberg | MD, PhD | Assistant Professor (CHS) | 608 | Human Oncology | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Imaging Biomarkers for Advanced Prostate Cancer: Project Description: Advanced imaging modalities such as positron emission tomography (PET) and magnetic resonance imaging (MRI) have made a dramatic impact in the clinical management of patients with advanced prostate cancer. However, use of advanced imaging is primarily limited to staging (determining how advanced a primary tumor is or if it has spread). Another potentially powerful use of imaging is to use it to predict who will respond to therapy, or to monitor response during a therapy. However, in prostate cancer data supporting use of imaging in these ways is very limited. The overall aims of this project are to determine if PET imaging can be used to predict response to radiation therapy and monitor response during radiation therapy. There are two potential projects. The first is investigating pre-therapy and mid-therapy PET/MRI scans in men with high-risk localized prostate cancer undergoing definitive radiation therapy. This project is a formalized clinical trial that is nearing completion of its accrual. The second is investigating pre-therapy and mid-therapy PET scans in men with metastatic prostate cancer undergoing radiopharmaceutical therapy. This is a large retrospective study of patients with prostate cancer treated with radiopharmaceuticals at the University of Wisconsin, and may ultimately evolve into a multi-institutional study. These are both ongoing efforts, and both should ultimately yield multiple abstracts and papers. ____________________________________________________________________________ Role - Students will be involved with collection of clinical data (chart review or compiling data collected as part of the clinical trial). Students may also be involved with image analysis (as much as they are comfortable with depending on their skill set), as well as in comparing images to pathology data. Students will be working with medical residents and potentially graduate students from other labs in this analysis.; IRB Status - Project has IRBs in place; Skills - Prior experience with analyzing medical images will be helpful but is not required. | Imaging Biomarkers for Advanced Prostate Cancer | Project Description: Advanced imaging modalities such as positron emission tomography (PET) and magnetic resonance imaging (MRI) have made a dramatic impact in the clinical management of patients with advanced prostate cancer. However, use of advanced imaging is primarily limited to staging (determining how advanced a primary tumor is or if it has spread). Another potentially powerful use of imaging is to use it to predict who will respond to therapy, or to monitor response during a therapy. However, in prostate cancer data supporting use of imaging in these ways is very limited. The overall aims of this project are to determine if PET imaging can be used to predict response to radiation therapy and monitor response during radiation therapy. There are two potential projects. The first is investigating pre-therapy and mid-therapy PET/MRI scans in men with high-risk localized prostate cancer undergoing definitive radiation therapy. This project is a formalized clinical trial that is nearing completion of its accrual. The second is investigating pre-therapy and mid-therapy PET scans in men with metastatic prostate cancer undergoing radiopharmaceutical therapy. This is a large retrospective study of patients with prostate cancer treated with radiopharmaceuticals at the University of Wisconsin, and may ultimately evolve into a multi-institutional study. These are both ongoing efforts, and both should ultimately yield multiple abstracts and papers. | 0 | Students will be involved with collection of clinical data (chart review or compiling data collected as part of the clinical trial). Students may also be involved with image analysis (as much as they are comfortable with depending on their skill set), as well as in comparing images to pathology data. Students will be working with medical residents and potentially graduate students from other labs in this analysis. | Students will be expected to collect and analyze clinical data independently with mentorship meetings every week or every-other-week. If students are assisting with image analysis then they will be directly supervised, at least while learning how to do this. | Prior experience with analyzing medical images will be helpful but is not required. | Project has IRBs in place | Yes | Yes | Yes | UW undergraduates interested in research | No | No | Ranee Williams-Toycen williams@humonc.wisc.edu; Liz Forget forget@humonc.wisc.edu | John Floberg, jfloberg@humonc.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudaOevV1XiDgrwFQf8S4RzPS-LbYCcws4uO3rCA_GFpxrzRgq1Nr_RHUqz0KC0N0tk | ||||||||
| kerry.gannonloew@wisc.edu | Kerry | Gannon-Loew | MD, MS | Assistant Professor of Pediatrics | 608 | Pediatrics | Not currently interested or available for Non-Shapiro research mentoring of medical students | Adolescents and Addiction: This project is focused on investigating two very timely topics affecting adolescents’ health- substance use and technology. Both substance use and problematic internet use can lead to a variety of negative consequences, including effects on mental health, relationships and academic performance. This summer, a student would participate in a secondary data project focused on the association between substance use and problematic internet use. The student would be involved in planning analyses, interpreting findings, and contributing to presentations and publications. Further, although we have seen rates of adolescent substance use decline in recent years, overdose remains a leading cause of death among teens. Changes in the drug supply (fentanyl) and availability of substances increases the risk to adolescents’ health. Because of this, it is critical to train future pediatricians and other providers seeing adolescents across healthcare settings to identify and treat substance use disorders in teens. The student would also have an opportunity to assess the current evidence and shape future curricula on adolescent substance use for medical students and residents at SMPH. There are additional opportunities based on the student’s goals and interests to be involved in other secondary data projects. ____________________________________________________________________________ Role - Variable selection, analysis and interpretation of data, with the opportunity for abstract submission and manuscript writing; literature review. ; IRB Status - Approved; Skills - Enthusiasm towards learning about teens and their health | Adolescents and Addiction | This project is focused on investigating two very timely topics affecting adolescents’ health- substance use and technology. Both substance use and problematic internet use can lead to a variety of negative consequences, including effects on mental health, relationships and academic performance. This summer, a student would participate in a secondary data project focused on the association between substance use and problematic internet use. The student would be involved in planning analyses, interpreting findings, and contributing to presentations and publications. Further, although we have seen rates of adolescent substance use decline in recent years, overdose remains a leading cause of death among teens. Changes in the drug supply (fentanyl) and availability of substances increases the risk to adolescents’ health. Because of this, it is critical to train future pediatricians and other providers seeing adolescents across healthcare settings to identify and treat substance use disorders in teens. The student would also have an opportunity to assess the current evidence and shape future curricula on adolescent substance use for medical students and residents at SMPH. There are additional opportunities based on the student’s goals and interests to be involved in other secondary data projects. | 1 | Variable selection, analysis and interpretation of data, with the opportunity for abstract submission and manuscript writing; literature review. | Enthusiasm towards learning about teens and their health | Approved | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | Yes | Unsure / Depends | Megan Moreno, moreno@wisc.edu | Kerry Gannon-Loew, kerry.gannonloew@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueLS1ADqllfbRL7vVYVKALyBp7P17Q0HZF4wSAwZjQx3JxmIYPc_Mc0XELbUjX4SCo | ||||||||||
| gblitzer@humonc.wisc.edu | Grace | Blitzer | MD | Assistant Professor | Human Oncology | Research Electives for credit | Circulating tumor DNA in uterine cancer: Our project is investigating a blood test to help identify which women with endometrial cancer (the most common type of uterine cancer) should get chemotherapy, radiation therapy, or a combination of both. This blood test examines the circulating tumor DNA from endometrial cancer, as well as the mutations in the endometrial cancer’s DNA. We have collected blood samples as a pilot clinical trial to determine if this test can detect endometrial cancer DNA and determine if this DNA and its mutations are associated with how women with endometrial cancer do. Ultimately we hope ctDNA will be able to personalize treatments for women with endometrial cancer and improve survival. This project needs a medical student to compile clinical data, run analyses to determine ctDNA and clinical associations, and write up a potential pilot manuscript. ____________________________________________________________________________ Role - Chart review, data analysis, writing; IRB Status - Approved; Skills - Knowledge of Epic | Laura Huffman, MD, Assistant Professor | Obstetrics & Gynecology | huffman3@wisc.edu | Circulating tumor DNA in uterine cancer | Our project is investigating a blood test to help identify which women with endometrial cancer (the most common type of uterine cancer) should get chemotherapy, radiation therapy, or a combination of both. This blood test examines the circulating tumor DNA from endometrial cancer, as well as the mutations in the endometrial cancer’s DNA. We have collected blood samples as a pilot clinical trial to determine if this test can detect endometrial cancer DNA and determine if this DNA and its mutations are associated with how women with endometrial cancer do. Ultimately we hope ctDNA will be able to personalize treatments for women with endometrial cancer and improve survival. This project needs a medical student to compile clinical data, run analyses to determine ctDNA and clinical associations, and write up a potential pilot manuscript. | 0 | Chart review, data analysis, writing | Knowledge of Epic | Approved | No | No (plan to use Dean's Office Funds) | I am not certain - the student will need their own laptop computer. I can provide software/data tools | Not currently available to mentor other students | No | No | N/A | Grace Blitzer, gblitzer@humonc.wisc.edu -- Co-Mentor: Laura Huffman, MD, Assistant Professor | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufc3L1Rrtu4W8v6dZIfb2Mn5ebuX6zaFcCRttqciicQA1uDWwhJ3jmxOcHOLNsKyRs | ||||||||
| whiting@ortho.wisc.edu | Paul | Whiting | MD | Dr. | 608 | Orthopedics and Rehabilitation | Not currently interested or available for Non-Shapiro research mentoring of medical students | Evaluating the Presence of Osteoperosis in Patients Sustaining Ankle Fractures Requiring Definitive Orthopedic Fixation: Ankle features are one of the most common orthopedic injuries. Many of these patients are treated operatively and observed to have poor bone quality. The aim of this study is study is to evaluate the presence of osteoporosis based upon CT and surgeon intra-operative evaluation in patients who sustain ankle fractures. ____________________________________________________________________________ Role - The student will perform a literature review on the subject and in the process, draft an introduction for the research manuscript. Throughout the summer, the student will perform retrospective chart reviews of patients eligible for inclusion in the study. This will involve reviewing clinical progress notes, operative reports, and radiology reports, along with basic interpretation of radiographs and CT scans. The student will also work closely with our departmental statistician to plan and later analyze any statistical analyses relevant to the study. The student will also work toward drafting a full manuscript later in the summer, along with preparing a poster for the Shapiro Fall Research Symposium. Finally, there will be opportunities for the student to shadow Orthopaedic surgeons in clinic and in the operating room throughout the summer.; IRB Status - Ongoing; Skills - Proficiency in Excel, medical chart review/navigating EHR, ability to learn and apply basic X-ray interpretation skills, attention to detail and data organization and analysis, effective oral and communication skills, independent problem solving skills | Orthopedic Trauma | Dr. Jacquelyn Dunahoe | dunahoe@ortho.wisc.edu | Orthopedics and Rehabilitation | Orthopedic Trauma | Evaluating the Presence of Osteoperosis in Patients Sustaining Ankle Fractures Requiring Definitive Orthopedic Fixation | Ankle features are one of the most common orthopedic injuries. Many of these patients are treated operatively and observed to have poor bone quality. The aim of this study is study is to evaluate the presence of osteoporosis based upon CT and surgeon intra-operative evaluation in patients who sustain ankle fractures. | 0 | The student will perform a literature review on the subject and in the process, draft an introduction for the research manuscript. Throughout the summer, the student will perform retrospective chart reviews of patients eligible for inclusion in the study. This will involve reviewing clinical progress notes, operative reports, and radiology reports, along with basic interpretation of radiographs and CT scans. The student will also work closely with our departmental statistician to plan and later analyze any statistical analyses relevant to the study. The student will also work toward drafting a full manuscript later in the summer, along with preparing a poster for the Shapiro Fall Research Symposium. Finally, there will be opportunities for the student to shadow Orthopaedic surgeons in clinic and in the operating room throughout the summer. | As described above (and below), the student will be expected to work fairly independently on chart reviews after receiving appropriate training from the faculty mentor, orthopaedic resident (co-mentor), and our clinical research coordinator. Ongoing oversight and mentoring will be provided throughout the summer. | Proficiency in Excel, medical chart review/navigating EHR, ability to learn and apply basic X-ray interpretation skills, attention to detail and data organization and analysis, effective oral and communication skills, independent problem solving skills | Ongoing | No | Yes | Yes | Not currently available to mentor other students | No | No | Kris Sladky, Ortho Trauma Research Coordinator – sladky@ortho.wisc.edu; otrc@ortho.wisc.edu Dr. Paul Whiting – whiting@ortho.wisc.edu Dr. Jacquelyn Dunahoe - dunahoe@ortho.wisc.edu | Paul Whiting, whiting@ortho.wisc.edu -- Co-Mentor: Dr. Jacquelyn Dunahoe dunahoe@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudEi3Y4Z4ZqKTH4mwo62fGGcdzLSTYZfSA9P2yNegolq3rgvXFDWzHvG9latmo98G0 | ||||
| zafars@surgery.wisc.edu | Nabeel | Zafar | MD MPH | Assistant Professor of Surgery | 4.104.467.225 | Surgery | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Using AI to address disparities in Pancreas Cancer: In this project we will work on developing an AI assisted nurse navigation system to address disparities in access to care for patients with pancreatic cancer ____________________________________________________________________________ Role - Help in developing the data that is required to train AI models on. Student will annotate cross-sectional imaging reports for patients which will then be used to develop a LLM (by radiology and medical physics). Students will have opportunities to work with a multidisciplinary team and understand how AI models are developed and tested; IRB Status - submited; Skills - Nothing additional | Surgical Oncology | Using AI to address disparities in Pancreas Cancer | In this project we will work on developing an AI assisted nurse navigation system to address disparities in access to care for patients with pancreatic cancer | 0 | Help in developing the data that is required to train AI models on. Student will annotate cross-sectional imaging reports for patients which will then be used to develop a LLM (by radiology and medical physics). Students will have opportunities to work with a multidisciplinary team and understand how AI models are developed and tested | This work can be done independently | Nothing additional | submited | pending | Surgery department funds | Yes | MPH students, PhD students | No | Yes | gray@surgery.wisc.edu | Nabeel Zafar, zafars@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufp05GltDR_VKYl4lurydmXFMi3q_v7uKfwVBJrtmA2rc20mmBXE6JFhSo-Wjzc4I0 | ||||||||
| zafars@surgery.wisc.edu | Nabeel | Zafar | MD MPH | Assistant Professor of Surgery | 4.104.467.225 | Surgery | Shorter term projects, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Patient Journey Mapping to understand care-pathways in pancreas cancer: This qualitative study will understand the patient experience. We will understand the challenges faced by diverse patient populations of different backgrounds to better understand disparities in access to care. ____________________________________________________________________________ Role - Students will consent enroll and interview patients and map out their journey. They will work in a muldisciplinary team and understand how to apply systems engineering models in the healthcare setting. They will understand disparities in cancer care. ; IRB Status - need to submit; Skills - a positive attitude | Surgical Oncology | Patient Journey Mapping to understand care-pathways in pancreas cancer | This qualitative study will understand the patient experience. We will understand the challenges faced by diverse patient populations of different backgrounds to better understand disparities in access to care. | 0 | Students will consent enroll and interview patients and map out their journey. They will work in a muldisciplinary team and understand how to apply systems engineering models in the healthcare setting. They will understand disparities in cancer care. | They will be able to function independently. There are other members of the team that will support and supervise | a positive attitude | need to submit | No | Department of surgery | Yes | MPH students, PhD students | No | Yes | gray@surgery.wisc.edu | Nabeel Zafar, zafars@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueI0iydGxSeWucLngoZWtkhfJxSVAHQvn2AwHk8IqnlVNNpxd_RsTtelVTvl-ufi88 | ||||||||
| zafars@surgery.wisc.edu | Nabeel | Zafar | MD MPH | Assistant Professor of Surgery | 4.104.467.225 | Surgery | Shorter term projects, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Validating tools to assess financial toxicity and quality of life for cancer patients in Ethiopia: In this project we will translate and validate tools to asses quality of life and financial toxicity amongst patients with gastrointestinal cancers in Ethiopia. ____________________________________________________________________________ Role - The student will lead the project, working with multidisciplinary team, will help translate and validate tools to Amharic. Student will work with physicians and staff in Hawassa, Ethiopia to complete this. The work will involve designing questionnaires, administering these questionnaires, data analysis and writing. ; IRB Status - need to submit; Skills - A good attitude. Data management. cultural sensitivity. basic data analysis | Surgical Oncology | Validating tools to assess financial toxicity and quality of life for cancer patients in Ethiopia | In this project we will translate and validate tools to asses quality of life and financial toxicity amongst patients with gastrointestinal cancers in Ethiopia. | 1 | The student will lead the project, working with multidisciplinary team, will help translate and validate tools to Amharic. Student will work with physicians and staff in Hawassa, Ethiopia to complete this. The work will involve designing questionnaires, administering these questionnaires, data analysis and writing. | partial independence | A good attitude. Data management. cultural sensitivity. basic data analysis | need to submit | No | Department of Surgery | Yes | MPH students, PhD students | No | Yes | gray@surgery.wisc.edu | Nabeel Zafar, zafars@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuenqN3ZiJCg6Feo9xe53L7T-UxnaNaauqtM7s5pdIO4Bqm50suIhlSyA6npbkJVwxU | ||||||||
| mmora2@wisc.edu | Maria | Mora Pinzon | MD, MS | Assistant Professor | 6.088.902.524 | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Role of social media messages in delivering medically accurate and culturally appropriate information: Communities of color suffered a disproportionate impact from the COVID-19 pandemic. The lack of access to culturally appropriate accurate information, and targeted disinformation campaigns created doubt in science and healthcare systems which might have played a role in sustaining health disparities related to COVID-19. Public health experts recognize the importance of enlisting respected and well-known community leaders to help explain the health message around the COVID-19 vaccine as a component to persuade skeptics. To address the need for culturally appropriate content responsive to community needs, our team formed by a group of experts in communications and health research, community individuals, and community partners created and disseminated culturally and medically appropriate messages to share on social media platforms through community advocates. Between June 2020 and Feb 2023, we created approximately 1000 unique informational tools that were disseminated in over 1200 posts and garnered over 200,000 impressions and over 8,000 engagements. The numbers demonstrate that we have successfully reached a large group of individuals from communities of color in Wisconsin, and have identified the strategies to increase the dissemination of information. Our project evaluated the role of different leaders and roles in sharing community health messages and translated community-based practice principles into the digital world using community-centered approaches to accomplish the goals of our study. For this project the selected student will perform a literature review on the topic, assist with the data analysis and prepare a manuscript for publication. Furthermore, the student will participate in the creation of community-summaries to share the results with community partners and individuals. For information of my lab: morapinzonlab.medicine.wisc.edu ____________________________________________________________________________ Role - Perform a Literature Review, data analysis and preparation of results for publication.; IRB Status - N/A; Skills - Previous experience writing articles or abstract preferred. | Geriatrics and Gerontology | Role of social media messages in delivering medically accurate and culturally appropriate information | Communities of color suffered a disproportionate impact from the COVID-19 pandemic. The lack of access to culturally appropriate accurate information, and targeted disinformation campaigns created doubt in science and healthcare systems which might have played a role in sustaining health disparities related to COVID-19. Public health experts recognize the importance of enlisting respected and well-known community leaders to help explain the health message around the COVID-19 vaccine as a component to persuade skeptics. To address the need for culturally appropriate content responsive to community needs, our team formed by a group of experts in communications and health research, community individuals, and community partners created and disseminated culturally and medically appropriate messages to share on social media platforms through community advocates. Between June 2020 and Feb 2023, we created approximately 1000 unique informational tools that were disseminated in over 1200 posts and garnered over 200,000 impressions and over 8,000 engagements. The numbers demonstrate that we have successfully reached a large group of individuals from communities of color in Wisconsin, and have identified the strategies to increase the dissemination of information. Our project evaluated the role of different leaders and roles in sharing community health messages and translated community-based practice principles into the digital world using community-centered approaches to accomplish the goals of our study. For this project the selected student will perform a literature review on the topic, assist with the data analysis and prepare a manuscript for publication. Furthermore, the student will participate in the creation of community-summaries to share the results with community partners and individuals. For information of my lab: morapinzonlab.medicine.wisc.edu | 0 | Perform a Literature Review, data analysis and preparation of results for publication. | Previous experience writing articles or abstract preferred. | N/A | Yes | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | Yes | N/A | Maria Mora Pinzon, mmora2@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufb8Ti69m2UM66TB7z7gfsaO9W9kflh_mJYJ9CS8Bu2S7FZckwpMZouuBw6YTis1vA | |||||||||
| schwarze@surgery.wisc.edu | Gretchen | Schwarze | MD | Professor of Surgery | 6.088.526.405 | Surgery | Shorter term projects, Research Electives for credit | Using SEIPS analysis to understand how clinical momentum impacts care of older adults with life limiting illness: We will use systems engineering, SEIPS 2.0, to code data related to decisions about surgery and mechanical ventilation. We have collected the raw data and now it needs to be coded and analyzed. My lab focuses on patient-clinician communication about high-stakes treatment decisions (patientpreferences.org) and understanding the systems in which we work is an important component of intervening to support better treatment decisions. ____________________________________________________________________________ Role - coding, analyzing, presenting data, learning more about how interpersonal decisions are contextualized within a larger system. ; IRB Status - approved; Skills - good communication skills, works well with others | Vascular | Using SEIPS analysis to understand how clinical momentum impacts care of older adults with life limiting illness | We will use systems engineering, SEIPS 2.0, to code data related to decisions about surgery and mechanical ventilation. We have collected the raw data and now it needs to be coded and analyzed. My lab focuses on patient-clinician communication about high-stakes treatment decisions (patientpreferences.org) and understanding the systems in which we work is an important component of intervening to support better treatment decisions. | 0 | coding, analyzing, presenting data, learning more about how interpersonal decisions are contextualized within a larger system. | moderate degree of independence | good communication skills, works well with others | approved | Yes | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Yes | Joanna Houston (grants admin for training programs, DOS) | Gretchen Schwarze, schwarze@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufOuyHxiNDui1nyxGlusmIOmAc4-AKGZ1AFhbqXqJSSDPzMty2NXwnZy0a9qZjr0Ms | ||||||||
| sleeth@wisc.edu | Carolyn | Sleeth | MD, MPH | Assistant Professor of Pediatrics | 6.082.792.350 | Pediatrics | Not currently interested or available for Non-Shapiro research mentoring of medical students | Can I Get a Note for School? Healthcare Provider and School Perspectives on Medically Excused Absences: This is a mixed-methods study looking at how healthcare providers and school personnel formulate and use excuse notes for medically excused absences. The goal of this study is to improve workflows for providers, optimize communication between healthcare providers and schools, and work to reduce chronic absenteeism. The student would help with data review and manuscript writing, with the potential for authorship. ____________________________________________________________________________ Role - Data review and manuscript writing ; IRB Status - Approved; Skills - Comfort with manuscript writing | General Pediatrics and Adolescent Medicine | Can I Get a Note for School? Healthcare Provider and School Perspectives on Medically Excused Absences | This is a mixed-methods study looking at how healthcare providers and school personnel formulate and use excuse notes for medically excused absences. The goal of this study is to improve workflows for providers, optimize communication between healthcare providers and schools, and work to reduce chronic absenteeism. The student would help with data review and manuscript writing, with the potential for authorship. | 1 | Data review and manuscript writing | Moderate | Comfort with manuscript writing | Approved | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Yes | Kristi Kotleski - kkotleski@wisc.edu | Carolyn Sleeth, sleeth@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudAWrY9DEwRa2TRhzAnRhaOjqhfM0dnRCjiKLhEzOBijS1jn0XVnrn24TEOqsxC-s4 | ||||||||
| cmorgan@wisc.edu | Courtney | Morgan | MD | Associate Professor | 0 | Surgery | Not currently interested or available for Non-Shapiro research mentoring of medical students | Comparative Analysis of Primary and Residual Type B Aortic Dissections: Insights into Long-Term Prognosis and Reintervention Rates: Our goal is to compare the physiological differences that impact outcomes between primary TBAD and residual TBAD following TAAD surgical repair involving cardiopulmonary bypass. Additionally, we aim to identify potential factors that may reduce the incidence of reintervention during cardiopulmonary bypass. We hypothesize that continuous flow in cardiopulmonary bypass could be advantageous in stabilizing the intimal tear flap, which may move back and forth with normal physiological pulsatile flow. ____________________________________________________________________________ Role - Data mining, chart review, analysis, writing abstracts, contributing to manuscript; IRB Status - Approved; Skills - Chart Review, comfort with Epic, interest in analysis | Vascular | Leah Gober, MD | lgober@wisc.edu | Surgery | Vascular | Comparative Analysis of Primary and Residual Type B Aortic Dissections: Insights into Long-Term Prognosis and Reintervention Rates | Our goal is to compare the physiological differences that impact outcomes between primary TBAD and residual TBAD following TAAD surgical repair involving cardiopulmonary bypass. Additionally, we aim to identify potential factors that may reduce the incidence of reintervention during cardiopulmonary bypass. We hypothesize that continuous flow in cardiopulmonary bypass could be advantageous in stabilizing the intimal tear flap, which may move back and forth with normal physiological pulsatile flow. | 0 | Data mining, chart review, analysis, writing abstracts, contributing to manuscript | Moderate | Chart Review, comfort with Epic, interest in analysis | Approved | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | No | N/A | Courtney Morgan, cmorgan@wisc.edu -- Co-Mentor: Leah Gober, MD lgober@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuf3XOh7TWhnyTe76cT8CQprKmupAaBzB7v_FhXNU7Ql_uzXFuvOTFw2USNCOiwOZdw | ||||
| popvicas@medicine.wisc.edu | Aurora | Pop-Vicas | MD, MPH | Associate Professor, Infectious Disease, UWSMPH | Medicine | Shorter term projects | Assessment of functional status and cognitive performance in people living with Long COVID: This ICTR-funded study was a community-engaged cross-sectional cohort study that aimed to determine the impact of COVID infection on cognition, functional status and activities of daily living on a diverse sample of adults living in Dane County, We enrolled and evaluated 132 adults with at least one prior COVID-19 infection (cases) and 42 adults without any prior known COVID infection (controls). We compared the objective performance of cases and controls on various neurocognitive and functional cognition instruments, and the self-reported performance on measures of functional status and activities of daily living assessed by methodological instruments previously validated for these purposes. At this point, we have completed enrollment and evaluation of all participants, finalized the study dataset, and are conducting multiple statistical analyses. Interested students from the Shapiro Program could join our project at the stage of manuscript writing. Specifically, we can mentor students for the following planned manuscripts: 1) challenges in recruiting a non-biased sample for studies focused on Long COVID (Primary mentor Dr Farrar Edwards); and 2) proposed screening tools to detect the "brain fog" phenotype of Long COVID in clinical practice (Primary mentor Dr. Pop-Vicas) https://ictr.wisc.edu/bio/farrar-edwards-dorothy/ https://kinesiology.education.wisc.edu/research/dorothy-edwards-research/ https://www.medicine.wisc.edu/directory/pop-vicas_aurora ____________________________________________________________________________ Role - Manuscript writing. ; IRB Status - N/A; Skills - Prior experience with clinical research writing a plus, but not required | Infectious Disease | Dorothy Farrar-Edwards, PhD; Professor, Associated Dean of Research for School of Education; | dfedwards@wisc.edu | Medicine | Geriatrics and Gerontology, Kinesiology, Education | Assessment of functional status and cognitive performance in people living with Long COVID | This ICTR-funded study was a community-engaged cross-sectional cohort study that aimed to determine the impact of COVID infection on cognition, functional status and activities of daily living on a diverse sample of adults living in Dane County, We enrolled and evaluated 132 adults with at least one prior COVID-19 infection (cases) and 42 adults without any prior known COVID infection (controls). We compared the objective performance of cases and controls on various neurocognitive and functional cognition instruments, and the self-reported performance on measures of functional status and activities of daily living assessed by methodological instruments previously validated for these purposes. At this point, we have completed enrollment and evaluation of all participants, finalized the study dataset, and are conducting multiple statistical analyses. Interested students from the Shapiro Program could join our project at the stage of manuscript writing. Specifically, we can mentor students for the following planned manuscripts: 1) challenges in recruiting a non-biased sample for studies focused on Long COVID (Primary mentor Dr Farrar Edwards); and 2) proposed screening tools to detect the "brain fog" phenotype of Long COVID in clinical practice (Primary mentor Dr. Pop-Vicas) https://ictr.wisc.edu/bio/farrar-edwards-dorothy/ https://kinesiology.education.wisc.edu/research/dorothy-edwards-research/ https://www.medicine.wisc.edu/directory/pop-vicas_aurora | 2 | Manuscript writing. | Both mentors have extensive experience mentoring trainees and plan to supervise and help as needed, while making this an enjoyable experience for the student. | Prior experience with clinical research writing a plus, but not required | N/A | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Yes | Rachel Flilipiak, MHA; Infectious Disease Operations Manager. email: rbfilipiak@medicine.wisc.edu | Aurora Pop-Vicas, popvicas@medicine.wisc.edu -- Co-Mentor: Dorothy Farrar-Edwards, PhD; Professor, Associated Dean of Research for School of Education; dfedwards@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufC_3VQN0kdRXzFgM18U22BjAoA1cxtxB_l5ubt5mI3EXnCS3sz6wlSvUjzGYMCohs | |||||
| 02/04/2025 | DOMES@ORTHO.WISC.EDU | Chris | Domes | MD | Assistant Prof | 5.035.156.966 | Orthopedics and Rehabilitation | Shorter term projects | Malabsorbative disorders for the orthopedic suregon: I would like to write a review paper on malabsorbative disorders aimed at educating orthopedics surgeons about common disorders, evaluation and treatment. ____________________________________________________________________________ Role - Lit review and writing; IRB Status - NA; Skills - lit review and writing | Trauma | Malabsorbative disorders for the orthopedic suregon | I would like to write a review paper on malabsorbative disorders aimed at educating orthopedics surgeons about common disorders, evaluation and treatment. | 1 | Lit review and writing | moderate | lit review and writing | NA | No | maybe | Yes | PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | Yes | Yes | NA | Chris Domes, DOMES@ORTHO.WISC.EDU -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuerRgsv564YIo-87lUToIzz4mBVLSUD2qeGk_1_FvYLp214Tj2MN6Itf6rs9YP8rxw | |||||||
| 02/04/2025 | npulia@wisc.edu | Nicole | Rogus-Pulia | PhD | Associate Professor | 6.083.472.368 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Salivary and Oral Health Profiles in Patients in the Emergency Department : The Swallowing and Salivary Bioscience Laboratory Salivary is a translational research program that focuses on the underlying factors contributing to swallowing disorders (dysphagia). Dysphagia can lead to aspiration pneumonia, and studies suggest that a significant portion of suspected community-acquired bacterial pneumonia cases may actually be due to distinct, dysphagia-related aspiration syndromes. A recent study was conducted in older adults with pneumonia who presented to the Emergency Department, which involved investigating swallow function, salivary production, and patient report of mouth dryness. The proposed project involves analyzing the data related to salivary characteristics in older adults with pneumonia presenting to the ED.The student will be responsible for performing literature searches, compiling data to prepare for analysis, assisting with analysis, and writing up results for dissemenation in a peer-reviewed journal. SSBL website: https://ssbl.wisc.edu/ ____________________________________________________________________________ Role - Student will organize data, assist with analysis, prepare data for publication, and lead manuscript development. ; IRB Status - IRB approved; Skills - Strong written communication skills | Geriatrics | Sara Gustafson | segustafson@wisc.edu | Medicine | Geriatrics | Salivary and Oral Health Profiles in Patients in the Emergency Department | The Swallowing and Salivary Bioscience Laboratory Salivary is a translational research program that focuses on the underlying factors contributing to swallowing disorders (dysphagia). Dysphagia can lead to aspiration pneumonia, and studies suggest that a significant portion of suspected community-acquired bacterial pneumonia cases may actually be due to distinct, dysphagia-related aspiration syndromes. A recent study was conducted in older adults with pneumonia who presented to the Emergency Department, which involved investigating swallow function, salivary production, and patient report of mouth dryness. The proposed project involves analyzing the data related to salivary characteristics in older adults with pneumonia presenting to the ED.The student will be responsible for performing literature searches, compiling data to prepare for analysis, assisting with analysis, and writing up results for dissemenation in a peer-reviewed journal. SSBL website: https://ssbl.wisc.edu/ | 1 | Student will organize data, assist with analysis, prepare data for publication, and lead manuscript development. | Moderate | Strong written communication skills | IRB approved | Yes | Yes | Yes | Not currently available to mentor other students | Unsure / Depends | Unsure / Depends | N/A | Nicole Rogus-Pulia, npulia@wisc.edu -- Co-Mentor: Sara Gustafson segustafson@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuc56h5PWIQCpwfdEQeLl9wZcGLrrCjR1r2lQEOrP_VSSFdvSL2WCY7caBIGMa9jzek | |||
| 02/04/2025 | npulia@wisc.edu | Nicole | Rogus-Pulia | PhD | Associate Professor | 6.083.472.368 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Development of Novel Thickened Liquids for Swallowing Disorders : The Swallowing and Salivary Bioscience Laboratory Salivary is a translational research program that focuses on the underlying factors contributing to swallowing disorders, including the role of saliva in eating and drinking. We are currently enrolling participants in a study examining the effect of the rheological properties of saliva on swallow function and how the combination of thickened liquids and saliva facilitate swallowing, which includes conducting videofluoroscopic swallow studies. The student will be involved in study visits with participants, collecting swallowing and salivary data, and managing the data. SSBL website: https://ssbl.wisc.edu/ ____________________________________________________________________________ Role - Student will be trained in research study visit and salivary collection procedures. The student will be responsible for compiling and managing data and preparing data for analysis. ; IRB Status - IRB-approved; Skills - Strong communication and organizational skills; highly attentive to details | Geriatrics | Sara Gustafson | segustafson@wisc.edu | Medicine | Geriatrics | Development of Novel Thickened Liquids for Swallowing Disorders | The Swallowing and Salivary Bioscience Laboratory Salivary is a translational research program that focuses on the underlying factors contributing to swallowing disorders, including the role of saliva in eating and drinking. We are currently enrolling participants in a study examining the effect of the rheological properties of saliva on swallow function and how the combination of thickened liquids and saliva facilitate swallowing, which includes conducting videofluoroscopic swallow studies. The student will be involved in study visits with participants, collecting swallowing and salivary data, and managing the data. SSBL website: https://ssbl.wisc.edu/ | 1 | Student will be trained in research study visit and salivary collection procedures. The student will be responsible for compiling and managing data and preparing data for analysis. | Moderate | Strong communication and organizational skills; highly attentive to details | IRB-approved | Yes | Yes | Yes | Not currently available to mentor other students | No | No | N/A | Nicole Rogus-Pulia, npulia@wisc.edu -- Co-Mentor: Sara Gustafson segustafson@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueQ3o0gu3B9HjxtoBz9NFSxCN1er1YlYzhiFZiYKzV2FEBq2rMFOtZ9NhS0i5UIuWA | |||
| 02/10/2025 | wschrage@wisc.edu | William | Schrage | PhD | Professor | 6.082.627.715 | Other | Shorter term projects, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Vascular control of brain blood flow: sex comparisons: There are several avenues to partake in this NIH funded work comparing Cerebral Blood Flow (CBF) control across healthy males and females. First, help analyze PC VIPR MRI data that quantifies CBF in 11 major cerebral arteries, looking for patterns in flow, CSA, and shear stress. Second, help analyze a subset of data in subjects who have anxiety/depression to see how those conditions change CBF. Third, expose PBMC to stress (like LPS) and compare immune responses between sexes. Fourth use exercise to change carotid artery function in adults with pre diabetes. All of these can use a motivated curious medical student to come to fruition with my graduate students.. ____________________________________________________________________________ Role - Technical assistant, data recorder, data analyzer.; IRB Status - approved; Skills - Strong interest in cardiovascular physiology | Kinesiology | Vascular control of brain blood flow: sex comparisons | There are several avenues to partake in this NIH funded work comparing Cerebral Blood Flow (CBF) control across healthy males and females. First, help analyze PC VIPR MRI data that quantifies CBF in 11 major cerebral arteries, looking for patterns in flow, CSA, and shear stress. Second, help analyze a subset of data in subjects who have anxiety/depression to see how those conditions change CBF. Third, expose PBMC to stress (like LPS) and compare immune responses between sexes. Fourth use exercise to change carotid artery function in adults with pre diabetes. All of these can use a motivated curious medical student to come to fruition with my graduate students.. | 1 | Technical assistant, data recorder, data analyzer. | moderate. Once trained on techniques, a lot of flexibility and responsibility. | Strong interest in cardiovascular physiology | approved | Yes | No (plan to use Dean's Office Funds) | if PBMC study, I will work with collaborator for supplies. Otherwise yes | Not currently available to mentor other students | No | No | Greg Dierks is dept administrator | William Schrage, wschrage@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueMSHX70DZOXP0DsOrabXlbik-BdBMxw8OCA06al-4MH3oqJKxm_zavw9VPUYGKCYE | |||||||
| 02/10/2025 | spiker@ortho.wisc.edu | Andrea | Spiker | M.D. | Assistant Professor, Orthopedic Surgery; Director, Hip Preservation Program; Director, Sports Medicine Fellowship | 608 | Orthopedics and Rehabilitation | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Do early post-operative patient reported outcomes predict return to sport timeline?: We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. We will identify those patients who played sports at baseline, and then evaluate whether early post-operative patient reported outcomes (PROs) predict the time to return to sport. This will involve a retrospective chart review of clinic and physical therapy notes in order to determine this timepoint. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. My co-PI, Dr. Kieth Knurr (PT) will be integral in the mentorship for this project as well. ____________________________________________________________________________ Role - A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. ; IRB Status - IRB approval for our registry and for this project fall under our IRB umbrella protocol; Skills - Excel and Word. Organizational skills and good communication with the other members of the team. | Sports Medicine | Other | Hip Preservation | Haley Smith & Keith Knurr | hsmith@ortho.wisc.edu, Knurr@ortho.wisc.edu | Orthopedics and Rehabilitation | Sports Medicine | Do early post-operative patient reported outcomes predict return to sport timeline? | We would like to involve a summer research student in our IRB-approved patient reported outcome (PRO) Hip Preservation Registry at the University of Wisconsin and in a research study utilizing the data collected in this registry. This project will provide the student with the opportunity to learn about the basics of a prospectively collected patient reported outcomes registry, collaborating with statisticians, clinicians, research professionals, residents in training, and allows him or her to participate in the writing of the project manuscript and submission of the final project, as well as in the preparation and presentation of posters and/or podiums if/when they are accepted to local, national and/or international conferences. Our specific projects involves a retrospective review of all patients who have undergone hip arthroscopy and/or periacetabular osteotomy. We will identify those patients who played sports at baseline, and then evaluate whether early post-operative patient reported outcomes (PROs) predict the time to return to sport. This will involve a retrospective chart review of clinic and physical therapy notes in order to determine this timepoint. I would welcome the student to shadow in my orthopaedic clinic and operating rooms (as much or as little as desired) if he or she would be interested in gaining a clinical and operative experience. As part of this specific project, the student would be highly encouraged to observe clinic and operative cases involving the patient group we are studying (sports medicine, hip arthroscopy and periacetabular osteotomy) to have a more complete understanding of the importance of this study. My co-PI, Dr. Haley Smith, will also gladly welcome the student into her clinic and operating room. My co-PI, Dr. Kieth Knurr (PT) will be integral in the mentorship for this project as well. | 0 | A portion of the student’s time would be dedicated to entering patient data into the Hip Preservation Registry, obtained through a medical record chart review. Specific tasks related to the project detailed above include maintaining the patient list and measures obtained, and being a direct liaison between the attending surgeon and physician, athletic trainers, orthopedic surgery resident, Hip Preservation research coordinator and statisticians involved in this project. The student may additionally be paired with a resident and will work with a research coordinator who can assist him/her in the project as well as abstract and manuscript preparation. Additionally, the student will attend weekly check-in meetings with the surgeon PI (Dr. Spiker) and/or co-PI (Dr. Smith) to discuss progress of the research as well as to follow a summer research curriculum created by the PI. This curriculum is geared at introducing the student to clinical research and how to complete research projects. | Moderate - We will give specific instructions and direction, but the student will need to be self-motivated to complete the project and make the most out of the experience. | Excel and Word. Organizational skills and good communication with the other members of the team. | IRB approval for our registry and for this project fall under our IRB umbrella protocol | No | Yes | Yes | Not currently available to mentor other students | Unsure / Depends | Unsure / Depends | Heidi Ableidinger (Ableidinger@ortho.wisc.edu) Orthopedics Student Services Coordinator; Amie Armstrong (armstrong@ortho.wisc.edu) Hip Preservation Research Coordinator | Andrea Spiker, spiker@ortho.wisc.edu -- Co-Mentor: Haley Smith & Keith Knurr hsmith@ortho.wisc.edu, Knurr@ortho.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucS9E-IwbigHjVzalG4r7DPDjFGG0Hc3g-sg28FaaEs1ehu43foTTVwrIFt7k73FFo | |
| 02/11/2025 | bakke@surgery.wisc.edu | Katherine | Bakke | MD, MPH | Assistant Professor | 5.038.055.285 | Surgery | Shorter term projects, Research Electives for credit | Elevating rural surgeons in the academic discourse: My two research projects for a summer student involve descriptive analysis of surgical textbooks and question banks and the occurrence of rural surgery within these educational tools. The hypothesis is that these educational tools do not represent rural surgery, presenting a bias in the academic/educational space against the unique pathologies, decision making, and disease management needed for practicing surgery in a rural setting. The first is looking simply at how rural surgery is represented in surgical textbooks, if mentioned at all. The second is looking at trauma-themed questions in a question bank to see if they represent traumatic injury/mechanism that may be unique or prevalent in the rural vs urban population (ex: over representation of penetrating trauma vs blunt trauma in the question bank). ____________________________________________________________________________ Role - Data gathering, data analysis (qualitative analysis and descriptive statistics), paper writing; IRB Status - N/A; Skills - None, but experience or familiarity with qualitative methods is useful | Acute Care and Regional General Surgery | Elevating rural surgeons in the academic discourse | My two research projects for a summer student involve descriptive analysis of surgical textbooks and question banks and the occurrence of rural surgery within these educational tools. The hypothesis is that these educational tools do not represent rural surgery, presenting a bias in the academic/educational space against the unique pathologies, decision making, and disease management needed for practicing surgery in a rural setting. The first is looking simply at how rural surgery is represented in surgical textbooks, if mentioned at all. The second is looking at trauma-themed questions in a question bank to see if they represent traumatic injury/mechanism that may be unique or prevalent in the rural vs urban population (ex: over representation of penetrating trauma vs blunt trauma in the question bank). | 2 | Data gathering, data analysis (qualitative analysis and descriptive statistics), paper writing | Quite independent | None, but experience or familiarity with qualitative methods is useful | N/A | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | Yes | No | N/A | Katherine Bakke, bakke@surgery.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudmqi649LxSrqzEgt_hJTnJws7tsKGsDrAoxLI3NBa1Ee9l8hmD3DZ-bdTBMrkxLhI | |||||||
| mklutz@medicine.wisc.edu | Megan | Lutz | MD | Assistant Professor of Medicine | 8.479.610.699 | Medicine | Not currently interested or available for Non-Shapiro research mentoring of medical students | Dysplasia detection rate with texture and color enhancement imaging technology as compared to chromoendoscopy in patients with inflammatory bowel disease undergoing surveillance colonoscopy : A student would attend enodsocpy sessions to collect data on characteristics of the patients, procedure, and polyp detection. Student would also be welcome to attend clinic for additional exposure ____________________________________________________________________________ Role - Data collection and analysis, drafting of poster and possible manuscript; IRB Status - N/A; Skills - None | Gastroenterology | Dr. Freddy Caldera | fcaldera@medicine.wisc.edu | Medicine | Gastroenterology | Dysplasia detection rate with texture and color enhancement imaging technology as compared to chromoendoscopy in patients with inflammatory bowel disease undergoing surveillance colonoscopy | A student would attend enodsocpy sessions to collect data on characteristics of the patients, procedure, and polyp detection. Student would also be welcome to attend clinic for additional exposure | 0 | Data collection and analysis, drafting of poster and possible manuscript | None | N/A | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | Yes | N/A | Megan Lutz, mklutz@medicine.wisc.edu -- Co-Mentor: Dr. Freddy Caldera fcaldera@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudkXLYZ6c80ChrNm_KVlVLfPdgoKctwQO1tt0lcSiWTd2svVBVXjcDePvvkOWSoxM0 | |||||
| grimes@urology.wisc.edu | Matthew | Grimes | MD | Assistant Professor | Urology | Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Reconstructive Urology Research: I am a reconstructive urologist in the UW Department of Urology where I maintain a busy clinical practice and clinical and translational research lab. My primary goals for your summer are to introduce to you the excellent field of urology and propel a research project forward. I have worked with a Shapiro Student every year for the last 5 years with all mentees publishing a first author paper and/or presenting at a national meeting. I have a portfolio of clinical and translational research projects many of which are ideal for the Shaprio Scholarship mechanism. We would work together to determine the best project fit for you in accordance with your interests and career goals. Examples of active projects include 1) image (MRI) based assessment of lower urinary tract biomechanics and urethral stricture, 2) patient centered outcomes after gender affirming surgery, 3) defining the epidemiology and current management of urethral stricture disease, and 4)comparing inflammatory cell populations in urethral stricture patients. You would be working in an established research group within the NIH funded UW O’Brien Center for Benign Urology Research. In addition to research opportunities, students will have the opportunity to shadow in urology clinic and the operating room in accordance with their interests. ____________________________________________________________________________ Role - Data collection (both EHR and bench top depending on project focus), data analysis to include basic biostatistics, writing with goal of submitting a first author manuscript.; IRB Status - Approved; Skills - Interest only | Reconstructive Urology Research | I am a reconstructive urologist in the UW Department of Urology where I maintain a busy clinical practice and clinical and translational research lab. My primary goals for your summer are to introduce to you the excellent field of urology and propel a research project forward. I have worked with a Shapiro Student every year for the last 5 years with all mentees publishing a first author paper and/or presenting at a national meeting. I have a portfolio of clinical and translational research projects many of which are ideal for the Shaprio Scholarship mechanism. We would work together to determine the best project fit for you in accordance with your interests and career goals. Examples of active projects include 1) image (MRI) based assessment of lower urinary tract biomechanics and urethral stricture, 2) patient centered outcomes after gender affirming surgery, 3) defining the epidemiology and current management of urethral stricture disease, and 4)comparing inflammatory cell populations in urethral stricture patients. You would be working in an established research group within the NIH funded UW O’Brien Center for Benign Urology Research. In addition to research opportunities, students will have the opportunity to shadow in urology clinic and the operating room in accordance with their interests. | 1 | Data collection (both EHR and bench top depending on project focus), data analysis to include basic biostatistics, writing with goal of submitting a first author manuscript. | Interest only | Approved | Yes | Yes | Yes | RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | Yes | N/A | Matthew Grimes, grimes@urology.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufhdXtvXZwhXuPoPqAjkabgUB7W8-gx_G-tt2lNyaYv24gmOGT6mYqALcYs6ZZcHps | |||||||||||
| 05/01/2025 | uelmen@wisc.edu | Johnny | Uelmen | PhD | Assistant Professor of Epidemiology | Population Health Sciences | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Funding arrangements may be available at later times, so please inquire directly | Modeling and forecasting zoonotic disease risk through a One Health lens: Our lab investigates emerging and re-emerging infectious diseases using a One Health approach that integrates environmental, animal, and human health. We focus on the spatial and temporal dynamics of zoonotic disease transmission, working to identify ecological drivers, predict outbreak risks, and inform prevention strategies. Medical students will have the opportunity to engage in interdisciplinary summer research projects that support this mission. Potential activities include: Data Analysis and Modeling: Work with epidemiological, ecological, and climate data to model disease risk using statistical and machine learning approaches. GIS and Spatial Epidemiology: Conduct spatial analyses using remote sensing and mapping software to identify disease hotspots and transmission corridors. Field Work: Participate in field sampling, including animal trapping, vector surveillance, and environmental data collection at partner field sites. Laboratory Work: Assist in vector identification, pathogen screening, and insectary-based experiments to study disease ecology under controlled conditions. This is an excellent opportunity for students interested in infectious disease, public health, global health, and translational research at the human-animal-environment interface. ____________________________________________________________________________ Role - Depending on level of experience and time to commit, students can serve the role of primary researcher to support level. Any effort will result in authorship roles on resulting manuscripts.; IRB Status - N/A; Skills - GIS (ArcGIS Pro) and basic statistical methods preferred, but not required. Willingness to connect human medicine to wildlife and environmental health is all that is required! | Modeling and forecasting zoonotic disease risk through a One Health lens | Our lab investigates emerging and re-emerging infectious diseases using a One Health approach that integrates environmental, animal, and human health. We focus on the spatial and temporal dynamics of zoonotic disease transmission, working to identify ecological drivers, predict outbreak risks, and inform prevention strategies. Medical students will have the opportunity to engage in interdisciplinary summer research projects that support this mission. Potential activities include: Data Analysis and Modeling: Work with epidemiological, ecological, and climate data to model disease risk using statistical and machine learning approaches. GIS and Spatial Epidemiology: Conduct spatial analyses using remote sensing and mapping software to identify disease hotspots and transmission corridors. Field Work: Participate in field sampling, including animal trapping, vector surveillance, and environmental data collection at partner field sites. Laboratory Work: Assist in vector identification, pathogen screening, and insectary-based experiments to study disease ecology under controlled conditions. This is an excellent opportunity for students interested in infectious disease, public health, global health, and translational research at the human-animal-environment interface. | 2 | Depending on level of experience and time to commit, students can serve the role of primary researcher to support level. Any effort will result in authorship roles on resulting manuscripts. | Can vary from novel to experienced | GIS (ArcGIS Pro) and basic statistical methods preferred, but not required. Willingness to connect human medicine to wildlife and environmental health is all that is required! | N/A | Multiple grants have been submitted or are in process | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | Unsure / Depends | Yes | Lisa Werning (werning@wisc.edu) & Milda Aksamitauskas (aksamitauska@wisc.edu) | Johnny Uelmen, uelmen@wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucM_P0_fnwhWwwKo9oKAs_C6323tB3vaK2JKQuL-Szoghrx6muOzJYKl_6rApbxEqc | |||||||||
| 02/04/2024 | smahrt@pediatrics.wisc.edu | Megan | Moreno | MD, MSEd, MPH | Professor of Pediatrics | 608 | Pediatrics | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Brain, Behavior and Well-being: The Brain, Behavior, and WellBeing (B3) Study investigates how technology and digital media can influence health behaviors and well-being in adolescents. The purpose of this study is to address the urgent need to understand how technology and digital media use could impact adolescent development and health. This project's website is b3study.org and our research team site is www.smahrtresearch.com. ____________________________________________________________________________ Role - Research team member involved in data collection, analysis planning, recruitment and all aspects of this project. May have opportunity to get exposure to fMRI portion of study as well as abstract planning and writing. ; IRB Status - Approved; Skills - Exposure to social media is a benefit | General Pediatrics and Adolescent Medicine | Bradley Kerr | bkerr@wisc.edu | Pediatrics | General Pediatrics and Adolescent Medicine | Brain, Behavior and Well-being | The Brain, Behavior, and WellBeing (B3) Study investigates how technology and digital media can influence health behaviors and well-being in adolescents. The purpose of this study is to address the urgent need to understand how technology and digital media use could impact adolescent development and health. This project's website is b3study.org and our research team site is www.smahrtresearch.com. | 1 | Research team member involved in data collection, analysis planning, recruitment and all aspects of this project. May have opportunity to get exposure to fMRI portion of study as well as abstract planning and writing. | Our team does expect a degree of initiative and independence in all team member's work, but also provides a supportive environment to learn and ask questions. | Exposure to social media is a benefit | Approved | Yes | Yes | Yes | DPT students, Genetic Counseling students, MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | Yes | Christine Richards (crichards9@wisc.edu) | Megan Moreno, smahrt@pediatrics.wisc.edu -- Co-Mentor: Bradley Kerr bkerr@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnucfurJcd3JlgwTFa_iaV8bplOXAx-xfqr45lNEDWB5mk2aJfbr5blB_Ta7FxSmM58I | |||
| 01/09/2024 | smahrt@pediatrics.wisc.edu | Megan | Moreno | MD, MSEd, MPH | Professor of Pediatrics | 608 | Pediatrics | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | American Academy of Pediatrics: This project is the American Academy of Pediatrics (AAP) Center of Excellence on Social Media and Youth Mental Health. Students will be fully immersed in work on this large national project alongside team members from UW Madison, U Michigan and the AAP. Duties will include addressing questions submitted by community members to the Center web portal using evidence based approaches, and being part of planning and implementing Center initiatives. The Center website is here: https://www.aap.org/en/patient-care/media-and-children/center-of-excellence-on-social-media-and-youth-mental-health/ ____________________________________________________________________________ Role - The student will get exposure and experiences across all aspects of this exciting Center of Excellence on Social Media and Youth Mental Health work. ; IRB Status - N/A; Skills - Literature review skills are a benefit | General pediatrics and adolescent medicine | Avery Salerno | aesalerno@wisc.edu | Pediatrics | General pediatrics and adolescent medicine | American Academy of Pediatrics | This project is the American Academy of Pediatrics (AAP) Center of Excellence on Social Media and Youth Mental Health. Students will be fully immersed in work on this large national project alongside team members from UW Madison, U Michigan and the AAP. Duties will include addressing questions submitted by community members to the Center web portal using evidence based approaches, and being part of planning and implementing Center initiatives. The Center website is here: https://www.aap.org/en/patient-care/media-and-children/center-of-excellence-on-social-media-and-youth-mental-health/ | 1 | The student will get exposure and experiences across all aspects of this exciting Center of Excellence on Social Media and Youth Mental Health work. | Independent work alongside team members to provdie support. | Literature review skills are a benefit | N/A | Yes | Yes | Yes | DPT students, Genetic Counseling students, MPH students, PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | No | Yes | Christine Richards (crichards9@wisc.edu) | Megan Moreno, smahrt@pediatrics.wisc.edu -- Co-Mentor: Avery Salerno aesalerno@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuccMgNa30kUCsdBEU_9oTye7ajpFQkBPfbIcOZEz3kcNfaizgj571BdRfhqHJ-WreE | |||
| agepner@medicine.wisc.edu | Adam | Gepner | MD | Associate Professor of Medicine | 6.085.778.048 | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity | Building a Successful Virtual Fitness Program for Older Adults (GeroFit Madison): This is a retrospective analysis of comparing health and fitness metrics in participants of the Gerofit Madison program compared with Veterans who participate in the Gerofit Madison Program for < 6 months or who observed the program but chose not to participate. Physical activity declines as we age and studies suggest that only 15% of adults over 65 years engage in regular physical activity. Lower levels of physical activity have been associated with functional and cognitive disability and poor health outcomes, specifically higher risk of cardiovascular disease events, frailty, and falls, all which can be improved with regular physical activity. Despite the well-established benefits of physical activity8 and advances in mobile health and telehealth technology, the use and the benefits of a virtual exercise program in older Veterans are lacking. Gerofit is a national VA exercise program that promotes physical and mental health and wellness for Veterans. Gerofit was designed to help Veterans stay active by improving or minimizing losses in strength, balance, flexibility and cardiovascular fitness. Veterans are provided with personalized exercise prescriptions by trained staff (exercise physiologists, nurses and physical therapists). Gerofit was started at the Durham VA in 1986, the program is now offered at 31 different VA Healthcare Systems around the country. The Madison VA hosts the largest and fastest growing Virtual Gerofit program in the country with ~ 200 regular participants. We plan a retrospective analysis of comparing health and fitness metrics and frailty outcomes in participants of the Gerofit Madison program (an all-virtual ongoing exercise program for Veterans over age 65) compared with age and sex matched Veterans who enroll in the program but stop attending within 6 months or who observe the program but elect not to participate. This study will compare anthropomorphic, laboratory data, functional metrics (sit to stand testing, arm curls, etc) and frailty markers in Gerofit participants compared to age and sex matched non-Gerofit participants. ____________________________________________________________________________ Role - A Shapiro Scholar will be responsible for the following (with guidance and supervision): 1. Reviewing background material and collecting articles on relevant topics including cardiovascular disease prevention, exercise and frailty. 2. Review and understand the Gerofit protocol and study techniques and limitations involved in retrospective analysis. 3. Review and analyze data. 4. Compose a research proposal/abstract/poster/manuscript; IRB Status - Approved; Skills - Skills with excel and powerpoint are helpful but not required. Some statistical and programming background is helpful but not required. | Cardiovascular Medicine | Medicine | Geriatrics and Gerontology | Building a Successful Virtual Fitness Program for Older Adults (GeroFit Madison) | This is a retrospective analysis of comparing health and fitness metrics in participants of the Gerofit Madison program compared with Veterans who participate in the Gerofit Madison Program for < 6 months or who observed the program but chose not to participate. Physical activity declines as we age and studies suggest that only 15% of adults over 65 years engage in regular physical activity. Lower levels of physical activity have been associated with functional and cognitive disability and poor health outcomes, specifically higher risk of cardiovascular disease events, frailty, and falls, all which can be improved with regular physical activity. Despite the well-established benefits of physical activity8 and advances in mobile health and telehealth technology, the use and the benefits of a virtual exercise program in older Veterans are lacking. Gerofit is a national VA exercise program that promotes physical and mental health and wellness for Veterans. Gerofit was designed to help Veterans stay active by improving or minimizing losses in strength, balance, flexibility and cardiovascular fitness. Veterans are provided with personalized exercise prescriptions by trained staff (exercise physiologists, nurses and physical therapists). Gerofit was started at the Durham VA in 1986, the program is now offered at 31 different VA Healthcare Systems around the country. The Madison VA hosts the largest and fastest growing Virtual Gerofit program in the country with ~ 200 regular participants. We plan a retrospective analysis of comparing health and fitness metrics and frailty outcomes in participants of the Gerofit Madison program (an all-virtual ongoing exercise program for Veterans over age 65) compared with age and sex matched Veterans who enroll in the program but stop attending within 6 months or who observe the program but elect not to participate. This study will compare anthropomorphic, laboratory data, functional metrics (sit to stand testing, arm curls, etc) and frailty markers in Gerofit participants compared to age and sex matched non-Gerofit participants. | 0 | A Shapiro Scholar will be responsible for the following (with guidance and supervision): 1. Reviewing background material and collecting articles on relevant topics including cardiovascular disease prevention, exercise and frailty. 2. Review and understand the Gerofit protocol and study techniques and limitations involved in retrospective analysis. 3. Review and analyze data. 4. Compose a research proposal/abstract/poster/manuscript | The scholar should be comfortable working independently and with our research team | Skills with excel and powerpoint are helpful but not required. Some statistical and programming background is helpful but not required. | Approved | Yes | Yes | Yes | DPT students, MPH students | No | No | Amy Hein - Amy.Hein@va.gov | Adam Gepner, agepner@medicine.wisc.edu -- Co-Mentor: | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuciIVIjUvlkmFLBWJjOJhHk8sL_uPaPQa9hW5GpT1T490myzrEC_E8QqtqoQRxL0Q0 | ||||||
| 12/09/2022 | dempsey@neurosurgery.wisc.edu | Robert | Dempsey | MD | Professor and Chair | 0 | Neurological Surgery | Shorter term projects | Pathophysiology of stroke, atherosclerosis and brain tumor: The Dempsey lab currently has multiple, but related research projects with focus on cerebral ischemia and brain injury, and tumor stem cell driven glioblastoma. Dr. Dempsey has lead a group of neurosurgeons and scientists dedicated to neurosurgical patient care. Our research focus includes; • The biochemistry of ischemic stroke brain edema and brain injury; Lipid changes and other factors in the formation of carotid artery atherosclerosis; The modification of adult progenitor/stem cells in brain after focal cerebral ischemia; Acute management of subarachnoid hemorrhage; Applied research in stroke, brain perfusion, subarachnoid hemorrhage and trauma; • The molecular and cellular Biology of post-stroke brain and embolic carotid diseases, atherosclerosis and its relationship to functional our come and cognitive impairment. We are also focusing on identification of blood biomarkers associated with stroke risk and outcome. • The other goals of our research include identification of the therapeutic targets, and elucidate the underlying mechanisms of tumor cell and stem cell survival, migration, and angiogenesis. We are particularly interested in the role of inflammation, proteases, and cytokines in regulating these physiological events that drive the development and progression of glioblastoma (GBM), a cancer of central nervous system. The soluble growth factors, cytokines, and extracellular matrix components in the microenvironment contribute significantly to the stem cell dynamics, development of neuronal tumors, and brain injury repair following stroke. ____________________________________________________________________________ Role - Students are required to follow protocols and safety procedures approved for our lab. They are expected to learn and get involved in the experimental procedures, lab maintenance, and maintain proper etiquette. They are expected to contribute to ongoing projects. Dr. Wesley will be the primary supervisor in lab. They will meet with Dr. Dempsey and the entire lab team during our biweekly lab meeting to discuss the progress of the project. They can also attend Neurological Surgery Grand Rounds and journal clubs several times throughout the summer to gain further knowledge of this field.; IRB Status - Approved; Skills - Some exposure to basic lab technique. However, we will train. | Umadevi Wesley PhD, Distinguished Scientist/Research Professor | wesley@neurosurgery.wisc.edu | Neurological Surgery | Pathophysiology of stroke, atherosclerosis and brain tumor | The Dempsey lab currently has multiple, but related research projects with focus on cerebral ischemia and brain injury, and tumor stem cell driven glioblastoma. Dr. Dempsey has lead a group of neurosurgeons and scientists dedicated to neurosurgical patient care. Our research focus includes; • The biochemistry of ischemic stroke brain edema and brain injury; Lipid changes and other factors in the formation of carotid artery atherosclerosis; The modification of adult progenitor/stem cells in brain after focal cerebral ischemia; Acute management of subarachnoid hemorrhage; Applied research in stroke, brain perfusion, subarachnoid hemorrhage and trauma; • The molecular and cellular Biology of post-stroke brain and embolic carotid diseases, atherosclerosis and its relationship to functional our come and cognitive impairment. We are also focusing on identification of blood biomarkers associated with stroke risk and outcome. • The other goals of our research include identification of the therapeutic targets, and elucidate the underlying mechanisms of tumor cell and stem cell survival, migration, and angiogenesis. We are particularly interested in the role of inflammation, proteases, and cytokines in regulating these physiological events that drive the development and progression of glioblastoma (GBM), a cancer of central nervous system. The soluble growth factors, cytokines, and extracellular matrix components in the microenvironment contribute significantly to the stem cell dynamics, development of neuronal tumors, and brain injury repair following stroke. | 0 | Students are required to follow protocols and safety procedures approved for our lab. They are expected to learn and get involved in the experimental procedures, lab maintenance, and maintain proper etiquette. They are expected to contribute to ongoing projects. Dr. Wesley will be the primary supervisor in lab. They will meet with Dr. Dempsey and the entire lab team during our biweekly lab meeting to discuss the progress of the project. They can also attend Neurological Surgery Grand Rounds and journal clubs several times throughout the summer to gain further knowledge of this field. | Somewhat - Fairly independent | Some exposure to basic lab technique. However, we will train. | Approved | Yes | Yes | Yes | PhD students | Yes | No | N/A | Robert Dempsey, dempsey@neurosurgery.wisc.edu -- Co-Mentor: Umadevi Wesley PhD, Distinguished Scientist/Research Professor wesley@neurosurgery.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufjaPGBiZcrL_NpP_0Pae5S0PvHb7M7h2oPaDBnk4BqNo6kyq8lKMiyBHeNigffjBI | |||||
| 01/10/2023 | awalaszek@wisc.edu | Art | Walaszek | MD | Professor | 608 | Psychiatry | Not currently interested or available for Non-Shapiro research mentoring of medical students | Improving dementia care in Wisconsin through education: Our team at the Wisconsin Alzheimer’s Institute works to improve the care of people with BPSD by teaching healthcare providers better assessment and management of BPSD and helping train the next generation of healthcare professionals to better detect and treat dementia. Specifically, our next project will examine the impact of BPSD education on feasibility and sustainability of new clinical practices, and the effectiveness of the education and BPSD strategies in improving clinical outcomes for patients living with dementia and their caregivers. More info: https://wai.wisc.edu/improving-dementia-care-wi/ ____________________________________________________________________________ Role - The student could be involved in data acquisition, data analysis, presenting outcomes, and collaborating with our team.; IRB Status - We have IRB approval; Skills - An interest in improving the care of persons living with dementia, literature reviews, data collection, and writing skills | Medicine | Geriatric Medicine | Tammy LeCaire, MS, PhD | tjlecaire@wisc.edu | Wisconsin Alzheimer’s Institute | Improving dementia care in Wisconsin through education | Our team at the Wisconsin Alzheimer’s Institute works to improve the care of people with BPSD by teaching healthcare providers better assessment and management of BPSD and helping train the next generation of healthcare professionals to better detect and treat dementia. Specifically, our next project will examine the impact of BPSD education on feasibility and sustainability of new clinical practices, and the effectiveness of the education and BPSD strategies in improving clinical outcomes for patients living with dementia and their caregivers. More info: https://wai.wisc.edu/improving-dementia-care-wi/ | 1 | The student could be involved in data acquisition, data analysis, presenting outcomes, and collaborating with our team. | Moderate; guidance and direction will be provided by PI, co-mentor and program coordinator | An interest in improving the care of persons living with dementia, literature reviews, data collection, and writing skills | We have IRB approval | No | Yes | Yes | Not currently available to mentor other students | Yes | Yes | Molly Schroeder, mjschroeder3@wisc.edu; Sarah Klein, sarah.klein@wisc.edu | Art Walaszek, awalaszek@wisc.edu -- Co-Mentor: Tammy LeCaire, MS, PhD tjlecaire@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufwV5Hyw2wMjpkANTabH5rIXRMt6WVdgpnmhM9d_1YlMgx-2wPpmF9jYq7yKwSeJ1g | |||
| rtstriker@wisc.edu | rob | striker | MD/PhD | Associate Professor | 608 | Medicine | Shorter term projects, Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Infectious cause of epilepsy: examine records from UKbiobank of people that have epilepsy and either do or do not have serologic evidence of Toxoplasmosis infection. Based on meta analysis from other countries we hypothesize this data set (several fold larger than any previously examined) will show those with serologic evidence of toxo exposure will have a ~4 fold higher risk of epilepsy. Data from UK biobank already shows for the first time that similiar to mouse studies toxo infection results in slightly smaller brains. This will be the first study with enough data that we can perhaps say how long after a toxo infection does the increase in epilepsy last, and does toxo increase all types of epilepsy or only certain focal types. ____________________________________________________________________________ Role - examine records from UKbiobank of people that have epilepsy and either do or do not have serologic evidence of Toxoplasmosis infection. Based on meta analysis from other countries we hypothesize this data set (several fold larger than any previously examined) will show those with serologic evidence of toxo exposure will have a ~4 fold higher risk of epilepsy. Data from UK biobank already shows for the first time that similiar to mouse studies toxo infection results in slightly smaller brains. This will be the first study with enough data that we can perhaps say how long after a toxo infection does the increase in epilepsy last, and does toxo increase all types of epilepsy or only certain focal types.; IRB Status - exempt; Skills - Excel, rudimentary statistics helpful but statisticians are involved | infectious diseases | Elizabeth Felton, Assistant Professor of Neurology | felton@neurology.wisc.edu | Neurology | Infectious cause of epilepsy | examine records from UKbiobank of people that have epilepsy and either do or do not have serologic evidence of Toxoplasmosis infection. Based on meta analysis from other countries we hypothesize this data set (several fold larger than any previously examined) will show those with serologic evidence of toxo exposure will have a ~4 fold higher risk of epilepsy. Data from UK biobank already shows for the first time that similiar to mouse studies toxo infection results in slightly smaller brains. This will be the first study with enough data that we can perhaps say how long after a toxo infection does the increase in epilepsy last, and does toxo increase all types of epilepsy or only certain focal types. | 0 | examine records from UKbiobank of people that have epilepsy and either do or do not have serologic evidence of Toxoplasmosis infection. Based on meta analysis from other countries we hypothesize this data set (several fold larger than any previously examined) will show those with serologic evidence of toxo exposure will have a ~4 fold higher risk of epilepsy. Data from UK biobank already shows for the first time that similiar to mouse studies toxo infection results in slightly smaller brains. This will be the first study with enough data that we can perhaps say how long after a toxo infection does the increase in epilepsy last, and does toxo increase all types of epilepsy or only certain focal types. | much of the work can be done at home, but I will meet with you weekly and there is a graduate student involved | Excel, rudimentary statistics helpful but statisticians are involved | exempt | No | No (plan to use Dean's Office Funds) | Yes | MPH students, PhD students, UW undergraduates interested in research | No | Yes | N/A | rob striker, rtstriker@wisc.edu -- Co-Mentor: Elizabeth Felton, Assistant Professor of Neurology felton@neurology.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnufFqCcF_cStIo5nP0Qt979N3LDK-vKqlERnul80_A633YIKJoTiIwhihVGYXAVpvKg | |||||
| mralbert@wisc.edu | Mark | Albertini | MD | Professor | 608 | Medicine | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | Administration of intratumoral immunocytokine to activate immune rejection of spontaneous canine melanoma: Canine malignant melanoma provides a clinically relevant, large animal model to study melanoma immunotherapy as it is similar to human melanoma with metastasis occurring via lymphatics or blood vessels to regional lymph nodes, lungs, liver, brain, and kidney. Further, companion canines develop melanoma spontaneously in the setting of an intact immune system, are of various ages, mixed gender, and share similar environmental exposures with their human counterparts. Thus, canine melanoma provides an informative model in which to investigate melanoma immunotherapies for subsequent human trials. The Shapiro project involves molecular and cellular immune analyses in canines as part of a VA Merit award to investigate intratumoral (IT) injection of hu14.18-Interleukin-2 (IL2) immunocytokine (IC), a recombinant fusion protein linking the GD2 disialoganglioside-reactive monoclonal antibody hu14.18 with IL2, in dogs with spontaneous melanoma. IT-IC leverages the tumor's mutated neoantigens and converts the injected tumor into an autologous vaccine. The project also involves participation in analysis of melanoma patients being evaluated in the University of Wisconsin Carbone Cancer Center (UWCCC) protocol #UW16134 entitled “Phase I/II Trial of Intratumoral Administration of Hu14.18-IL2, with Local Radiation, Nivolumab and Ipilimumab in Subjects with Advanced Melanoma”. Lab web site: https://www9a.medicine.wisc.edu/hematology-oncology/albertini-research ____________________________________________________________________________ Role - The student will be involved with the processing of canine blood samples as well as cellular and/or flow cytometry and/or molecular immune assay development using samples from normal dogs and analyses of dogs with melanoma participating in a clinical trial that involves intratumoral injection of hu14.18-IL2 immunocytokine (IC) into spontaneous melanoma tumors. In addition to activities in the laboratory, the student will attend the weekly melanoma clinic as well as the melanoma tumor board and melanoma research meetings. The student will also participate in evaluating melanoma patients in ongoing melanoma clinical trials at the University of Wisconsin. ; IRB Status - N/A; Skills - Skills involving sterile tissue culture and/or flow cytometry and/or molecular biology assays are required. Prior experience with cellular and/or molecular immunology is recommended. | Hematology/Medical Oncology/Palliative Care | Cindy Zuleger, PhD | clz@medicine.wisc.edu | Medicine | Hematology/Medical Oncology/Palliative Care | Administration of intratumoral immunocytokine to activate immune rejection of spontaneous canine melanoma | Canine malignant melanoma provides a clinically relevant, large animal model to study melanoma immunotherapy as it is similar to human melanoma with metastasis occurring via lymphatics or blood vessels to regional lymph nodes, lungs, liver, brain, and kidney. Further, companion canines develop melanoma spontaneously in the setting of an intact immune system, are of various ages, mixed gender, and share similar environmental exposures with their human counterparts. Thus, canine melanoma provides an informative model in which to investigate melanoma immunotherapies for subsequent human trials. The Shapiro project involves molecular and cellular immune analyses in canines as part of a VA Merit award to investigate intratumoral (IT) injection of hu14.18-Interleukin-2 (IL2) immunocytokine (IC), a recombinant fusion protein linking the GD2 disialoganglioside-reactive monoclonal antibody hu14.18 with IL2, in dogs with spontaneous melanoma. IT-IC leverages the tumor's mutated neoantigens and converts the injected tumor into an autologous vaccine. The project also involves participation in analysis of melanoma patients being evaluated in the University of Wisconsin Carbone Cancer Center (UWCCC) protocol #UW16134 entitled “Phase I/II Trial of Intratumoral Administration of Hu14.18-IL2, with Local Radiation, Nivolumab and Ipilimumab in Subjects with Advanced Melanoma”. Lab web site: https://www9a.medicine.wisc.edu/hematology-oncology/albertini-research | 0 | The student will be involved with the processing of canine blood samples as well as cellular and/or flow cytometry and/or molecular immune assay development using samples from normal dogs and analyses of dogs with melanoma participating in a clinical trial that involves intratumoral injection of hu14.18-IL2 immunocytokine (IC) into spontaneous melanoma tumors. In addition to activities in the laboratory, the student will attend the weekly melanoma clinic as well as the melanoma tumor board and melanoma research meetings. The student will also participate in evaluating melanoma patients in ongoing melanoma clinical trials at the University of Wisconsin. | Ability to independently review the literature related to the research project is required. While mentoring is provided in the lab, progressing to independence with laboratory analyses is expected. | Skills involving sterile tissue culture and/or flow cytometry and/or molecular biology assays are required. Prior experience with cellular and/or molecular immunology is recommended. | N/A | VA Merit Grant | Plan to apply to the Dept of Medicine for stipend support or use the Dean's Office Funds. I do not have separate funding to cover 50% of the Shapiro summer student's stipend. | Yes | PhD students, UW undergraduates interested in research | No | No | Dr. Cindy Zuleger: clz@medicine.wisc.edu | Mark Albertini, mralbert@wisc.edu -- Co-Mentor: Cindy Zuleger, PhD clz@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnudVfqoyjvw8EQQ6CQN45M_iXwY3moBMj6NMX6dMUGyIVpjqGqeCAzLiAlkBrjl1FXQ | ||||
| mralbert@wisc.edu | Mark | Albertini | M.D. | Professor | 608 | Medicine | Research Electives for credit, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship) | PIG-A mutant T-cells as a biomarker of response to immune checkpoint blockade in metastatic melanoma: Melanoma-reactive T-cells are lymphocytes that have been stimulated in vivo by tumor antigens to undergo cell division. As mutation is expected to occur preferentially in dividing cells, a clonal assay that selects for T-cells with a specific in vivo mutation could enrich for T-cells that have undergone repetitive in vivo cell division. The Albertini lab has studied selection of T-cells with mutation acquired in vivo in a reporter gene (the hypoxanthine guanine phosphoribosyltransferase (HPRT) gene) by in vivo harvesting of lymphocytes followed by clonal expansion in vitro in the presence of 6-thioguanine. Findings in melanoma patients demonstrate an increase in HPRT mutant frequency (MF) compared to normal controls. Despite the virtues of the HPRT mutation system, there are several deficiencies. Namely it is time consuming, expensive, and need for in vitro expansion. The phosphatidylinositol glycan class A (PIG-A) gene is one of four genes that code for the proteins constituting glucosamine acetyl (GlcNAc) transferase – a multimeric enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) anchor biosynthesis. PIG-A is located on the X-chromosome and therefore is hemizygous. Mutation in PIG-A gene results in a deficiency of surface expressions of all GPI-anchored proteins. A cloning assay for PIG-A mutant T-lymphocytes has been described, and it allows isolation of mutants for molecular and functional analyses without extensive cytokine-mediated growth in vitro and the manual scoring methods currently required for determination of HPRT mutant frequencies by cloning. The objective of this project is to validate and implement a rapid, fluorescence-activated cell sorter (FACS) based assay to quantitatively assess frequencies of somatic mutant T-cells (PIG-A mutants) in melanoma patients in vivo. Lab website: https://www9a.medicine.wisc.edu/hematology-oncology/albertini-research ____________________________________________________________________________ Role - The student will directly participate in the laboratory studies. The student will be trained in flow cytometry, sterile cell culture, and molecular assessment of T-cell receptor gene usage. In addition to the laboratory duties, the student will have involvement with melanoma patients on translational melanoma research studies ; IRB Status - This project is approved by the IRB.; Skills - Skills involving sterile tissue culture and/or flow cytometry and/or molecular biology assays are required. Prior experience with cellular and/or molecular immunology is recommended. | Hematology/Medical Oncology/Palliative Care | Cindy Zuleger | clz@medicine.wisc.edu | Medicine | Hematology/Medical Oncology/Palliative Care | PIG-A mutant T-cells as a biomarker of response to immune checkpoint blockade in metastatic melanoma | Melanoma-reactive T-cells are lymphocytes that have been stimulated in vivo by tumor antigens to undergo cell division. As mutation is expected to occur preferentially in dividing cells, a clonal assay that selects for T-cells with a specific in vivo mutation could enrich for T-cells that have undergone repetitive in vivo cell division. The Albertini lab has studied selection of T-cells with mutation acquired in vivo in a reporter gene (the hypoxanthine guanine phosphoribosyltransferase (HPRT) gene) by in vivo harvesting of lymphocytes followed by clonal expansion in vitro in the presence of 6-thioguanine. Findings in melanoma patients demonstrate an increase in HPRT mutant frequency (MF) compared to normal controls. Despite the virtues of the HPRT mutation system, there are several deficiencies. Namely it is time consuming, expensive, and need for in vitro expansion. The phosphatidylinositol glycan class A (PIG-A) gene is one of four genes that code for the proteins constituting glucosamine acetyl (GlcNAc) transferase – a multimeric enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) anchor biosynthesis. PIG-A is located on the X-chromosome and therefore is hemizygous. Mutation in PIG-A gene results in a deficiency of surface expressions of all GPI-anchored proteins. A cloning assay for PIG-A mutant T-lymphocytes has been described, and it allows isolation of mutants for molecular and functional analyses without extensive cytokine-mediated growth in vitro and the manual scoring methods currently required for determination of HPRT mutant frequencies by cloning. The objective of this project is to validate and implement a rapid, fluorescence-activated cell sorter (FACS) based assay to quantitatively assess frequencies of somatic mutant T-cells (PIG-A mutants) in melanoma patients in vivo. Lab website: https://www9a.medicine.wisc.edu/hematology-oncology/albertini-research | 0 | The student will directly participate in the laboratory studies. The student will be trained in flow cytometry, sterile cell culture, and molecular assessment of T-cell receptor gene usage. In addition to the laboratory duties, the student will have involvement with melanoma patients on translational melanoma research studies | Ability to independently review the literature related to the research project is required. While mentoring is provided in the lab, progressing to independence with laboratory analyses is expected. | Skills involving sterile tissue culture and/or flow cytometry and/or molecular biology assays are required. Prior experience with cellular and/or molecular immunology is recommended. | This project is approved by the IRB. | VA Merit Grant and and a gift from Ann's Hope Foundation | Plan to apply to the Dept of Medicine for stipend support or use the Dean's Office Funds. I do not have separate funding to cover 50% of the Shapiro summer student's stipend. | Yes | PhD students, UW undergraduates interested in research | No | No | Dr. Cindy Zuleger: clz@medicine.wisc.edu | Mark Albertini, mralbert@wisc.edu -- Co-Mentor: Cindy Zuleger clz@medicine.wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnuf4qujWALSnBKR-F0H-ZU0oAnZXdrRRSoDA4jpDjnQPMy5pdGnCePyo22aPf6yt_6o | ||||
| lschnapp@medicine.wisc.edu | Lynn | Schnapp | MD | Professor, Chair of Medicine | 608 | Medicine | Shorter term projects, Interested in serving as a mentor for a yearlong fellowship (e.g., ICTR Shapiro fellowship), Interested and funded to provide another yearlong mentoring opportunity, Willing to work with interested students to develop an appropriate research experience | Mechanisms in lung injury, inflammation and repair: Our lab is focused on the processes that govern acute lung injury and its resolution. In particular, we are interested in why lung injury resolves under certain circumstances (e.g., Acute Respiratory Distress Syndrome, pneumonia) but progresses to end-stage damage or fibrosis in other circumstances (e.g., emphysema or Idiopathic Pulmonary Fibrosis). To examine these questions, we use different mouse models of lung injury to examine the regulation of matrix remodeling and the role of the alveolar myofibroblasts in the resolution of injury and fibrosis. To complement these studies, we are analyzing bronchoalveolar lavage fluid and peripheral blood from patients with ARDS, HIV and other lung diseases using cutting-edge methodologies such as transcriptomics and proteomics to identify new pathways and molecular targets. https://www.medicine.wisc.edu/people-search/people/staff/7084/Schnapp_Lynn ____________________________________________________________________________ Role - The student would have the opportunity to assist in analyzing data from ongoing experiments with mice. The focus would be on assessing different parameters of lung injury, such as changes in lung permeability and histology, as well as cytokine levels and cellular content and composition in the bronchoalveolar lavage. Other opportunities include working with human and mouse lung cells in culture to examine their responses to inflammatory and profibrotic mediators and how these responses are altered by therapeutics being tested in the lab.; IRB Status - n/a; Skills - Previous experience in a lab setting is not required – just inquisitiveness and enthusiasm. | Pulmonary and Critical Care Medicine | Cell and Regenerative Biology | Carole Wilson, Research Associate Professor | cwilson@medicine.wisc.edu | Medicine | Pulmonary and Critical Care Medicine | Mechanisms in lung injury, inflammation and repair | Our lab is focused on the processes that govern acute lung injury and its resolution. In particular, we are interested in why lung injury resolves under certain circumstances (e.g., Acute Respiratory Distress Syndrome, pneumonia) but progresses to end-stage damage or fibrosis in other circumstances (e.g., emphysema or Idiopathic Pulmonary Fibrosis). To examine these questions, we use different mouse models of lung injury to examine the regulation of matrix remodeling and the role of the alveolar myofibroblasts in the resolution of injury and fibrosis. To complement these studies, we are analyzing bronchoalveolar lavage fluid and peripheral blood from patients with ARDS, HIV and other lung diseases using cutting-edge methodologies such as transcriptomics and proteomics to identify new pathways and molecular targets. https://www.medicine.wisc.edu/people-search/people/staff/7084/Schnapp_Lynn | 0 | The student would have the opportunity to assist in analyzing data from ongoing experiments with mice. The focus would be on assessing different parameters of lung injury, such as changes in lung permeability and histology, as well as cytokine levels and cellular content and composition in the bronchoalveolar lavage. Other opportunities include working with human and mouse lung cells in culture to examine their responses to inflammatory and profibrotic mediators and how these responses are altered by therapeutics being tested in the lab. | We can tailor the project to the student’s interests and aptitude. The student would work closely with lab personnel. | Previous experience in a lab setting is not required – just inquisitiveness and enthusiasm. | n/a | Yes | Yes | Yes | PhD students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/), UW undergraduates interested in research | 1. Attia EF, Akgün KM, Wongtrakool C, Goetz MB, Rodriguez-Barradas MC, Rimland D, Brown ST, Soo Hoo GW, Kim J, Lee PJ, Schnapp LM, Sharafkhaneh A, Justice AC, Crothers K. Increased risk of radiographic emphysema in HIV is associated with elevated soluble CD14 and nadir CD4. Chest. 1;146(6):1543-53. 2014. PMC4251616 2. Grazioli S, Gil S, An D, Kajikawa O, Farnand AW, Hanson JF, Birkland T, Chen P, Duffield J, Schnapp LM, Altemeier WA, Matute-Bello G. CYR61 (CCN1) overexpression induces lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 308(8):L759-65. 2015 3. Strange C, Senior RM, Sciurba F, O'Neal S, Morris A, Wisniewski SR, Bowler R, Hochheiser HS, Becich MJ, Zhang Y, Leader JK, Methe BA, Kaminski N, Sandhaus RA, GRADS Alpha-1 Study Group*. Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol. Ann Am Thorac Soc. 12(10):1551-60. 2015. PMC4627425. *listed collaborator 4. Moller DR, Koth LL, Maier LA, Morris A, Drake W, Rossman M, Leader JK, Collman RG, Hamzeh N, Sweiss NJ, Zhang Y, O'Neal S, Senior RM, Becich M, Hochheiser HS, Kaminski N, Wisniewski SR, Gibson KF, GRADS Sarcoidosis Study Group*. Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) Study. Sarcoidosis Protocol. Ann Am Thorac Soc. 12(10):1561-71 2015. PMID: 26193069. *listed collaborator 5. Gharib SA, Malur A, Huizar I, Barna BP, Kavuru MS, Schnapp LM*, Thomassen MJ*. Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells. Respir Res. 17(1):93. 2016 *Shared senior authorship. 6. Crothers K, Petrache I, Wongtrakool C, Lee PJ, Schnapp LM*, Gharib SA*. Widespread activation of immunity and pro‐inflammatory programs in peripheral blood leukocytes of HIV-infected patients with impaired lung gas exchange. Physiological Reports. 4(8) pii: e12756. 2016. PMC4848721. *Shared senior authorship. 7. Attia EF, Jolley SE, Crothers K, Schnapp LM*, Liles WC*. Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome. PLoS One. 11(2):e0149687. 2016 *Shared senior authorship. 8. Hung CF, Chow YH, Liles WC, Altemeier WA, Schnapp LM. Ablation of Pericyte-like Cells in Lungs by Oropharyngeal Aspiration of Diphtheria Toxin. Am J Respir Cell Mol Biol. 56(2):160-167 2017. PMC5359647. (Featured in “Red Alerts” highlighted articles) 9. Hung CF, Mittelsteadt KL, Brauer R, McKinney BL, Hallstrand TS, Parks WC, Chen P, Schnapp LM, Liles WC, Duffield JS, Altemeier WA. Lung pericyte-like cells are functional immune sentinel cells. Am J Physiol Lung Cell Mol Physiol. 312(4): L556-L567. 2017. PMC5407093. (Chosen for “APSselect” highlight) 10. Beiko T, Janech MG, Alekseyenko AV, Atkinson C, Coxson HO, Barth JL, Stephenson SE, Wilson CL, Schnapp LM, Barker A, Brantly M, Sandhaus RA, Silverman EK, Stoller JK, Trapnell B, Strange S, for QUANTUM-1 Investigators. Serum proteins associated with emphysema progression in severe alpha-1 antitrypsin deficiency. Chronic Obstr Pulm Dis. 4(3): 204-216. 2017 11. Mohan A, Malur A, McPeek M, Barna BP, Schnapp LM*, Thomassen MJ*, Gharib SA*. Transcriptional Survey of Alveolar Macrophages in a Murine Model of Chronic Granulomatous Inflammation Reveals Common Themes with Human Sarcoidosis. Am J Physiol Lung Cell Mol Physiol. 314(4):L617-L625, 2017. PMC5966779 *Shared senior authorship. 12. Stephenson SE, Wilson CL, Crothers K, Attia EF, Wongtrakool C, Petrache I, Schnapp LM. Impact of HIV Infection on Alpha-1 Antitrypsin in the Lung. Am J Physiol Lung Cell Mol Physiol. 314(4):L583-L592. 2017. PMC5966776 13. Hung CF, Wilson CL, Chow YH, Schnapp LM. Role of integrin alpha8 in murine model of lung fibrosis. PLoS One. 13(5):e0197937. 2018. PMC5973593. 14. Li P, Zhou Y, Goodwin AJ, Cook JA, Halushka PV, Zhang XK, Wilson CL, Schnapp LM, Zingarelli B, Fan H. Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis. J Infect Dis. 218(12):1995-2005, 2018. 15. Wilson CL, Stephenson SE, Higuero JP, Feghali-Bostwick C, Hung CF, Schnapp LM Characterization of human PDGFRβ-positive pericytes from IPF and non-IPF lungs. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 18. doi: 10.1152/ajplung.00289.2018. PMID:30335500 16. Roman J, Barnes TR, Kervitsky DJ, Cosgrove GP, Doherty DE, Tager AM, Richeldi L, White ES, Brenner DA, Schnapp LM, Hewitson TD, Jugdutt BI, McKinsey TA, Tosi JD, Crane S, Brown KK; Fibrosis Across Organs Symposium Working Group. The Fibrosis Across Organs Symposium: A Roadmap for Future Research Priorities. Am J Med Sci. 2019 May;357(5):405-410. PubMed PMID: 31010467. 17. Hung CF, Wilson CL, Schnapp LM. Pericytes in the Lung. Adv Exp Med Biol. 2019;1122:41-58. PubMed PMID: 30937862. 18. Li P, Wu Y, Goodwin AJ, Halushka PV, Wilson CL, Schnapp LM, Fan H. Generation of a new immortalized human lung pericyte cell line: a promising tool for human lung pericyte studies. Lab Invest 2021. 19. Stephenson SE, Wilson CL, Bond NG, Kaur A, Alvarez X, Midkiff CC, Schnapp LM. Pericytes as novel targets for HIV/SIV infection in the lung. Am J Physiol Lung Cell Mol Physiol 2020; 319: L848-l853. 20. Mohan A, Neequaye N, Malur A, Soliman E, McPeek M, Leffler N, Ogburn D, Tokarz DA, Knudson W, Gharib SA, Schnapp LM, Barna BP, Thomassen MJ. Matrix Metalloproteinase-12 Is Required for Granuloma Progression. Front Immunol 2020; 11: 553949. | Yes | jewerndli@medicine.wisc.edu | Lynn Schnapp, lschnapp@medicine.wisc.edu -- Co-Mentor: Carole Wilson, Research Associate Professor cwilson@medicine.wisc.edu | ||||
| fallahian@wisc.edu | Whitney | Fallahian | MD | Assistant Professor | 907 | Anesthesiology | Shorter term projects, Research Electives for credit | General Anesthesia vs Monitored Anesthesia Care During Mechanical Thrombectomy for Acute Stroke Treatment: Ischemic stroke accounts for nearly 1 in 19 deaths in the United States, ranking it fifth among all causes of death. Methods of acute stroke treatment are continuously evolving, with endovascular thrombectomy considered the gold standard. However, the anesthetic management of patients undergoing thrombectomy remains controversial. Multiple studies have shown that monitored anesthesia care (MAC) or procedural sedation leads to better outcomes compared to general anesthesia (GA), while others have shown no difference. We are performing a retrospective study comparing GA vs MAC obtained from a review of patients from the University of Wisconsin from 2017-2023 presenting with ischemic stroke who underwent mechanical thrombectomy. Our primary endpoint is functional outcome as measured by Modified Rankin Score (MRS) at 90 days. Secondary endpoints included in-hospital death, death at 90 days, time to procedure start, time to recanalization, total procedure duration, successful revascularization, ICU length of stay and total hospital length of stay. The project will mainly entail data collection and entry as well as working with our statician to analyze the data and then write up the findings for a peer- reviewed journal article. ____________________________________________________________________________ Role - The role of the students will involve data collection and entry, working with our department statician to analyze the data and then begin to write up the finding for a peer-reviewed journal article.; IRB Status - Exempt; Skills - Familiar with Excel | Neuroanesthesia | Corey Amlong | caamlong@wisc.edu | Anesthesiology | Neuroanesthesia | General Anesthesia vs Monitored Anesthesia Care During Mechanical Thrombectomy for Acute Stroke Treatment | Ischemic stroke accounts for nearly 1 in 19 deaths in the United States, ranking it fifth among all causes of death. Methods of acute stroke treatment are continuously evolving, with endovascular thrombectomy considered the gold standard. However, the anesthetic management of patients undergoing thrombectomy remains controversial. Multiple studies have shown that monitored anesthesia care (MAC) or procedural sedation leads to better outcomes compared to general anesthesia (GA), while others have shown no difference. We are performing a retrospective study comparing GA vs MAC obtained from a review of patients from the University of Wisconsin from 2017-2023 presenting with ischemic stroke who underwent mechanical thrombectomy. Our primary endpoint is functional outcome as measured by Modified Rankin Score (MRS) at 90 days. Secondary endpoints included in-hospital death, death at 90 days, time to procedure start, time to recanalization, total procedure duration, successful revascularization, ICU length of stay and total hospital length of stay. The project will mainly entail data collection and entry as well as working with our statician to analyze the data and then write up the findings for a peer- reviewed journal article. | 0 | The role of the students will involve data collection and entry, working with our department statician to analyze the data and then begin to write up the finding for a peer-reviewed journal article. | Moderate to Significant | Familiar with Excel | Exempt | No | No (plan to use Dean's Office Funds) | Yes | Not currently available to mentor other students | No | No | Jeremy Sullivan | Whitney Fallahian, fallahian@wisc.edu -- Co-Mentor: Corey Amlong caamlong@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueDmwpEyhj8qMXQUxd4CnkV7sy82dJ61QJBwOUx2ZN-oAQEm7K-Urk3H2fgZx1Z3A8 | ||||
| 03/01/2024 | sarah.davis@wisc.edu | Sarah | Davis | JD / MPA | Clinical Professor of Law / Director Center for Patient Partnerships | 608 | Other | Shorter term projects, Always happy to consider projects with med students interested in health advocacy and patient experiences research | Advocacy for Patients with Disabilities: Creating an Evidence-Based Provider Toolkit to Increase Health Equity: Patients with disabilities are a nationally recognized population with health disparities. Barriers to care are multifactorial and can include difficulty accessing physical clinic environments, negative attitudes, lack of knowledge, and insufficient time.1,2 In addition to usual medical care, patients often need access to disability specific resources (therapy, equipment, etc.). Providers play a key role in supporting access to these necessary resources, including writing Letters of Medical Necessity and supporting prior authorization and coverage denials. This role can be challenging for providers who are unfamiliar with the process and constrained by time allotted for office visits. There may be other unidentified challenges as well. The first goal of this project is to assess all known potential barriers or challenges to caring for patients with disabilities that exist for providers and whether and how they could be addressed through creation of resources (an advocacy toolkit). The focus of the study will be primary care. This information will be used to guide creation of an advocacy toolkit utilizing the expertise of physicians who specialize in the care of patients with disabilities and advocates at the Center for Patient Partnerships. The goal of the toolkit is to build capacity in providers and care teams to mitigate barriers to quality care and resource access for patients with disabilities, with the long-term goal of improving health equity. 1. Lagu T, Haywood C, Reimold K, DeJong C, Walker Sterling R, Iezzoni LI. ‘I Am Not The Doctor For You’: Physicians’ Attitudes About Caring for People with Disabilities. Health Aff (Milwood). 2002 Oct; 41(10):1387-1395. 2. Common Barriers to Participation Experienced by People with Disabilities. Centers for Disease Control and Prevention. Updated Sept 16, 2020. Accessed Feb 16, 2024. https://www.cdc.gov/ncbddd/disabilityandhealth/disability-barriers.html More information about the Center for Patient Partnerships, our research, and programing at patientpartnerships.wisc.edu. ____________________________________________________________________________ Role - Creation of a survey for primary care physicians to determine components of an advocacy toolkit that would be beneficial with the final goal being creation of an advocacy toolkit. The project includes creation of the survey, deployment, evaluation of results, and toolkit creation. The initial role will focus on analysis of existing resources revealed from the literature review and the survey with the goal of determining what would be most beneficial to include in an advocacy toolkit and starting the drafting process. The student(s) will build upon the extensive literature review done in Summer ’24.; IRB Status - No current IRB, we will apply for exempt status.; Skills - Attention to detail, effective oral and written communication skills. Proficiency or willingness to learn in literature review, IRB application, survey design, data analysis, and summary of findings. As needed student will be provided with training materials and resources at the UW Survey Center and Health Sciences Library. | Law / Center for Patient Partnerships | Medicine | Med Sciences (teach Selective) | Melissa Villegas | mvillegas3@wisc.edu | Pediatrics | Advocacy for Patients with Disabilities: Creating an Evidence-Based Provider Toolkit to Increase Health Equity | Patients with disabilities are a nationally recognized population with health disparities. Barriers to care are multifactorial and can include difficulty accessing physical clinic environments, negative attitudes, lack of knowledge, and insufficient time.1,2 In addition to usual medical care, patients often need access to disability specific resources (therapy, equipment, etc.). Providers play a key role in supporting access to these necessary resources, including writing Letters of Medical Necessity and supporting prior authorization and coverage denials. This role can be challenging for providers who are unfamiliar with the process and constrained by time allotted for office visits. There may be other unidentified challenges as well. The first goal of this project is to assess all known potential barriers or challenges to caring for patients with disabilities that exist for providers and whether and how they could be addressed through creation of resources (an advocacy toolkit). The focus of the study will be primary care. This information will be used to guide creation of an advocacy toolkit utilizing the expertise of physicians who specialize in the care of patients with disabilities and advocates at the Center for Patient Partnerships. The goal of the toolkit is to build capacity in providers and care teams to mitigate barriers to quality care and resource access for patients with disabilities, with the long-term goal of improving health equity. 1. Lagu T, Haywood C, Reimold K, DeJong C, Walker Sterling R, Iezzoni LI. ‘I Am Not The Doctor For You’: Physicians’ Attitudes About Caring for People with Disabilities. Health Aff (Milwood). 2002 Oct; 41(10):1387-1395. 2. Common Barriers to Participation Experienced by People with Disabilities. Centers for Disease Control and Prevention. Updated Sept 16, 2020. Accessed Feb 16, 2024. https://www.cdc.gov/ncbddd/disabilityandhealth/disability-barriers.html More information about the Center for Patient Partnerships, our research, and programing at patientpartnerships.wisc.edu. | 2 | Creation of a survey for primary care physicians to determine components of an advocacy toolkit that would be beneficial with the final goal being creation of an advocacy toolkit. The project includes creation of the survey, deployment, evaluation of results, and toolkit creation. The initial role will focus on analysis of existing resources revealed from the literature review and the survey with the goal of determining what would be most beneficial to include in an advocacy toolkit and starting the drafting process. The student(s) will build upon the extensive literature review done in Summer ’24. | Analysis of results of the literature review will be completed independently with direction from mentors and librarian. The student will work with feedback from mentors and survey center guidance to develop and deploy the survey. | Attention to detail, effective oral and written communication skills. Proficiency or willingness to learn in literature review, IRB application, survey design, data analysis, and summary of findings. As needed student will be provided with training materials and resources at the UW Survey Center and Health Sciences Library. | No current IRB, we will apply for exempt status. | No | No (plan to use Dean's Office Funds) | Yes | Genetic Counseling students, MPH students, RUSCH pre-med students (https://www.med.wisc.edu/education/rusch/) | No | Yes | Curran Cauldwood Cauldwood@wisc.edu | Sarah Davis, sarah.davis@wisc.edu -- Co-Mentor: Melissa Villegas mvillegas3@wisc.edu | https://docs.google.com/forms/d/e/1FAIpQLSdCag337tFe4KL9_6rQ-AEogBkv98RfZjTzQ6DxypNB_Z0sMQ/viewform?edit2=2_ABaOnueTUCSPpLE0W0P5sQ9k0JXnRC1CG4_CuljJOx5PC-vklOJ3awc5Net9GZxphPyD_xk | ||
| jschuster3@wisc.edu | Jessica | Schuster | MD | Radiation Oncology | 7.706.345.212 | Human Oncology | Shorter term projects | UW23028 - Radiation therapy in individuals with intellectual disabilities and social story development: As the life expectancy of people with intellectual disability (persons with ID) has increased over the last few decades, they have become more exposed to cancer risk. Intellectual disability is defined by significant limitations in both intellectual functioning and adaptive behavior, which comprises many everyday social and practical skills, and originates before the age of 18. In series from the UK, prevalence rates for cancer were shown to be increasing among persons with ID. In decedents with ID and cancer, more than a third had cancer diagnosed via emergency presentations. Almost half were at stage IV when diagnosed [2]. Care of persons with ID, particularly with cancer presents a challenge to caregivers and clinicians at all stages, from prevention to screening, detection, diagnosis, treatment, and follow-up. Emergency and late stage diagnosis, highlights need to better understand cancer care in persons with ID. Persons with ID may have difficulties in understanding his/her illness and treatment and navigating healthcare system as each person with ID has unique communications needs. [1] A better familiarity with this population's experiences within radiation oncology will likely improved knowledge of how to communicate diagnosis, risks, and treatment with persons with ID. This project is IRB-approved retrospective review of persons with ID within UW system that have had radiation oncology consult to better characterize current practices. Additionally will be opportunity to help develop a personalizable social story to support and facilitate improved understanding of cancer care for patients with ID. ____________________________________________________________________________ Role - IRB-approved retrospective review of persons with ID within UW system that have had radiation oncology consult to better characterize current practices. Additionally will be opportunity to help develop a personalizable social story to support and facilitate improved understanding of cancer care for patients with ID. ; IRB Status - Approved; Skills - n/a | UW23028 - Radiation therapy in individuals with intellectual disabilities and social story development | As the life expectancy of people with intellectual disability (persons with ID) has increased over the last few decades, they have become more exposed to cancer risk. Intellectual disability is defined by significant limitations in both intellectual functioning and adaptive behavior, which comprises many everyday social and practical skills, and originates before the age of 18. In series from the UK, prevalence rates for cancer were shown to be increasing among persons with ID. In decedents with ID and cancer, more than a third had cancer diagnosed via emergency presentations. Almost half were at stage IV when diagnosed [2]. Care of persons with ID, particularly with cancer presents a challenge to caregivers and clinicians at all stages, from prevention to screening, detection, diagnosis, treatment, and follow-up. Emergency and late stage diagnosis, highlights need to better understand cancer care in persons with ID. Persons with ID may have difficulties in understanding his/her illness and treatment and navigating healthcare system as each person with ID has unique communications needs. [1] A better familiarity with this population's experiences within radiation oncology will likely improved knowledge of how to communicate diagnosis, risks, and treatment with persons with ID. This project is IRB-approved retrospective review of persons with ID within UW system that have had radiation oncology consult to better characterize current practices. Additionally will be opportunity to help develop a personalizable social story to support and facilitate improved understanding of cancer care for patients with ID. | 1 | IRB-approved retrospective review of persons with ID within UW system that have had radiation oncology consult to better characterize current practices. Additionally will be opportunity to help develop a personalizable social story to support and facilitate improved understanding of cancer care for patients with ID. | Moderate | n/a | Approved | No | In department of human oncology | Yes | Not currently available to mentor other students | Yes | Yes | Julie Thomas | Jessica Schuster , jschuster3@wisc.edu -- Co-Mentor: | ||||||||||
| Timestamp | Email Address | Mentor First Name | Mentor Last Name | Degree | Title | Phone Number | Dept. | Non-Shapiro Opportunities | Project Information | Primary Department Division | Secondary Department | Secondary Department Division | Co-Mentor Name | Co-Mentor Email | Co-Mentor's Primary Department | Co-Mentor's Primary Department's Division | Project Title | Project Description | Open Slots | Student's Role | Degree of Independence Required | Skills Required | IRB Status of Project | Do you have current NIH or other external funding? | Do you have funding to cover 50% of the Shapiro summer student's stipend? | Do you have resources to provide all needed supplies to support the student research experience? | Are you interested in mentoring non-medical students? | Does your project focus, in part or fully, on medical education? | Is your project related (in part or completely) to public health (e.g., clinical QI, community health, program planning/evaluation, epidemiologic studies)? | Please include names and emails of key staff in your department or lab who will need to be informed of your incoming Shapiro students. | blank 1 | Mentor Information | Response |